| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0601976 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0510799 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0336749 |
| POU2F1 | POU class 2 homeobox 1 | 0.0336589 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0325673 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.031926 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0311705 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0297752 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0295986 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0292699 |
| ECT2 | epithelial cell transforming 2 | 0.0290386 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0286348 |
| NFIA | nuclear factor I/A | 0.0285224 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0282434 |
| PEG10 | paternally expressed 10 | 0.0281197 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0265043 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0261974 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.025746 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0257436 |
| H1-0 | H1.0 linker histone | 0.0256008 |
| MB21D2 | Mab-21 domain containing 2 | 0.0254951 |
| CDC73 | cell division cycle 73 | 0.0253336 |
| TLK2 | tousled-like kinase 2 | 0.0245834 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0244878 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0244081 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0239391 |
| USP15 | ubiquitin specific peptidase 15 | 0.0235406 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0234029 |
| ZNF217 | zinc finger protein 217 | 0.0230674 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0228917 |
| INTS13 | integrator complex subunit 13 | 0.0227509 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0218553 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0218126 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0216981 |
| SFRP4 | secreted frizzled-related protein 4 | 0.021665 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0214638 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0212738 |
| THBS1 | thrombospondin 1 | 0.0211633 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0209822 |
| SHROOM3 | shroom family member 3 | 0.0209595 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0207638 |
| LCA5 | Leber congenital amaurosis 5 | 0.0203398 |
| CENPE | centromere protein E, 312kDa | 0.0201303 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0201134 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0200752 |
| ARF1 | ADP-ribosylation factor 1 | 0.0200716 |
| GRM1 | glutamate receptor, metabotropic 1 | 0.0198986 |
| RBM33 | RNA binding motif protein 33 | 0.0198744 |
| MATR3 | matrin 3 | 0.0197988 |
| RIGI | RNA sensor RIG-I | 0.0195004 |
| NEK7 | NIMA-related kinase 7 | 0.0193888 |
| CLTC | clathrin, heavy chain (Hc) | 0.0192876 |
| MED13L | mediator complex subunit 13-like | 0.0191658 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0191477 |
| NPTN | neuroplastin | 0.0190233 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0189168 |
| TCP1 | t-complex 1 | 0.0188441 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0187439 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.018696 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0186484 |
| CERT1 | ceramide transporter 1 | 0.0184964 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0183569 |
| COLEC11 | collectin sub-family member 11 | 0.0182701 |
| RYBP | RING1 and YY1 binding protein | 0.0182167 |
| TMSB4X | thymosin beta 4, X-linked | 0.0181009 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0179883 |
| VGLL4 | vestigial-like family member 4 | 0.0176854 |
| NELL2 | NEL-like 2 (chicken) | 0.0176754 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0176375 |
| ZNF518A | zinc finger protein 518A | 0.0175654 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0174547 |
| MTMR3 | myotubularin related protein 3 | 0.0174163 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0172864 |
| HLTF | helicase-like transcription factor | 0.0172076 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0172072 |
| FBXO11 | F-box protein 11 | 0.0171298 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0170506 |
| RBM27 | RNA binding motif protein 27 | 0.0170454 |
| DMXL1 | Dmx-like 1 | 0.0170317 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0169434 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0168308 |
| RPL4 | ribosomal protein L4 | 0.0166779 |
| METAP2 | methionyl aminopeptidase 2 | 0.016642 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0166378 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0166169 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0166057 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0165328 |
| TTK | TTK protein kinase | 0.016522 |
| WDR43 | WD repeat domain 43 | 0.01642 |
| STARD3NL | STARD3 N-terminal like | 0.0163733 |
| GTF3A | general transcription factor IIIA | 0.0163301 |
| CTNNBL1 | catenin, beta like 1 | 0.0162826 |
| TPX2 | TPX2, microtubule-associated | 0.0162099 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0161926 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0161348 |
| IL6ST | interleukin 6 signal transducer | 0.0161222 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.0160182 |
| CENATAC | centrosomal AT-AC splicing factor | 0.0159643 |
| AGPS | alkylglycerone phosphate synthase | 0.0159142 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0157814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.20094 |
| VIM | vimentin | -0.158521 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14432 |
| PTMA | prothymosin, alpha | -0.134181 |
| COL11A1 | collagen, type XI, alpha 1 | -0.125297 |
| RPS8 | ribosomal protein S8 | -0.108693 |
| RPS27A | ribosomal protein S27a | -0.10791 |
| RPS16 | ribosomal protein S16 | -0.0976534 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0963756 |
| FTL | ferritin, light polypeptide | -0.082557 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0793934 |
| RPL31 | ribosomal protein L31 | -0.07675 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0759954 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.075965 |
| NTM | neurotrimin | -0.072975 |
| RPS12 | ribosomal protein S12 | -0.0719797 |
| RPLP1 | ribosomal protein, large, P1 | -0.0695982 |
| TENM3 | teneurin transmembrane protein 3 | -0.0680361 |
| RPL37 | ribosomal protein L37 | -0.0676584 |
| RPS6 | ribosomal protein S6 | -0.0667114 |
| RPL5 | ribosomal protein L5 | -0.0647492 |
| RPL23 | ribosomal protein L23 | -0.0639796 |
| RPL37A | ribosomal protein L37a | -0.0625451 |
| ENO1 | enolase 1, (alpha) | -0.0616572 |
| LDHA | lactate dehydrogenase A | -0.0585499 |
| RPL35A | ribosomal protein L35a | -0.0569267 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0565427 |
| RPL26 | ribosomal protein L26 | -0.0555151 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0552797 |
| B2M | beta-2-microglobulin | -0.0544947 |
| RPS25 | ribosomal protein S25 | -0.0533341 |
| PLPP1 | phospholipid phosphatase 1 | -0.0519338 |
| COL5A2 | collagen, type V, alpha 2 | -0.0510864 |
| RPS3 | ribosomal protein S3 | -0.050595 |
| UPP1 | uridine phosphorylase 1 | -0.050259 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0498078 |
| ANKRD33B | ankyrin repeat domain 33B | -0.048161 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0468664 |
| PGK1 | phosphoglycerate kinase 1 | -0.0459063 |
| RPL36A | ribosomal protein L36a | -0.0458128 |
| RPS13 | ribosomal protein S13 | -0.0455552 |
| RAD51B | RAD51 paralog B | -0.0449149 |
| UBC | ubiquitin C | -0.0448089 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0442017 |
| ACTG1 | actin gamma 1 | -0.0436278 |
| RPS27 | ribosomal protein S27 | -0.0431601 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0428618 |
| CADM2 | cell adhesion molecule 2 | -0.0427733 |
| RBM25 | RNA binding motif protein 25 | -0.0421729 |
| GNAS | GNAS complex locus | -0.0418565 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0416526 |
| PHIP | pleckstrin homology domain interacting protein | -0.0408169 |
| CALR | calreticulin | -0.0405113 |
| RPL9 | ribosomal protein L9 | -0.0403 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0401314 |
| APOE | apolipoprotein E | -0.0400612 |
| RPL30 | ribosomal protein L30 | -0.0400254 |
| RPL28 | ribosomal protein L28 | -0.0399793 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0398218 |
| RPS29 | ribosomal protein S29 | -0.0398079 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.039724 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.039612 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0390706 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0387355 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0385635 |
| COL3A1 | collagen, type III, alpha 1 | -0.0384974 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0384182 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.038319 |
| RPS19 | ribosomal protein S19 | -0.0374584 |
| RPL19 | ribosomal protein L19 | -0.0374152 |
| RPL36 | ribosomal protein L36 | -0.037091 |
| DSTN | destrin (actin depolymerizing factor) | -0.036902 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0367476 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0364369 |
| RPS24 | ribosomal protein S24 | -0.0362899 |
| RPL12 | ribosomal protein L12 | -0.0362385 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0359342 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0357533 |
| RPL11 | ribosomal protein L11 | -0.0357202 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0352242 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0350539 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0349906 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0345945 |
| LRRC4C | leucine rich repeat containing 4C | -0.0344493 |
| RLF | rearranged L-myc fusion | -0.0343985 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0343654 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0343142 |
| BBX | bobby sox homolog (Drosophila) | -0.0342278 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0341183 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0339938 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0338472 |
| CDH19 | cadherin 19, type 2 | -0.0336778 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0335412 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0334779 |
| SNX6 | sorting nexin 6 | -0.0333887 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.033337 |
| SQSTM1 | sequestosome 1 | -0.0330797 |
| RPS17 | ribosomal protein S17 | -0.0326114 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0324201 |
| ANXA2 | annexin A2 | -0.0321926 |
