| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.127584 |
| FLNB | filamin B, beta | 0.111926 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.104438 |
| TXNRD1 | thioredoxin reductase 1 | 0.100514 |
| NBEA | neurobeachin | 0.0929839 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0776743 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.072385 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0710211 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0678625 |
| AHNAK | AHNAK nucleoprotein | 0.0629748 |
| PYGB | phosphorylase, glycogen; brain | 0.0592782 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0587956 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0577579 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0556296 |
| TMSB4X | thymosin beta 4, X-linked | 0.0550923 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0544251 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0509177 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0508796 |
| ECT2 | epithelial cell transforming 2 | 0.0507982 |
| EGFR | epidermal growth factor receptor | 0.0493203 |
| S100A6 | S100 calcium binding protein A6 | 0.0485149 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.048238 |
| TMEM65 | transmembrane protein 65 | 0.0480329 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0469129 |
| HDAC9 | histone deacetylase 9 | 0.0460746 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0450369 |
| RTN4 | reticulon 4 | 0.0432224 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0420785 |
| TMEM41B | transmembrane protein 41B | 0.0382058 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0377496 |
| DUSP4 | dual specificity phosphatase 4 | 0.0375052 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0369792 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0363627 |
| EVI5 | ecotropic viral integration site 5 | 0.0363306 |
| ZNF292 | zinc finger protein 292 | 0.0359919 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0350798 |
| HDLBP | high density lipoprotein binding protein | 0.0350032 |
| RPLP0 | ribosomal protein, large, P0 | 0.0347778 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0339453 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0337977 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0336737 |
| TJP1 | tight junction protein 1 | 0.0335809 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0333314 |
| PARD3 | par-3 family cell polarity regulator | 0.0322434 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0319093 |
| MATR3 | matrin 3 | 0.031547 |
| LOXL3 | lysyl oxidase-like 3 | 0.0312668 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0312416 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0311487 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0310995 |
| RNF145 | ring finger protein 145 | 0.0309462 |
| CCND1 | cyclin D1 | 0.0309049 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0308521 |
| ATP9B | ATPase, class II, type 9B | 0.0298854 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0298297 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0297616 |
| S100A4 | S100 calcium binding protein A4 | 0.0297056 |
| PRELID2 | PRELI domain containing 2 | 0.0295549 |
| EZR | ezrin | 0.0292318 |
| USP3 | ubiquitin specific peptidase 3 | 0.0290193 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0288509 |
| SRPK2 | SRSF protein kinase 2 | 0.0287304 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0283 |
| GLI2 | GLI family zinc finger 2 | 0.0282115 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0281319 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0278839 |
| UBE3A | ubiquitin protein ligase E3A | 0.0273333 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.026784 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0267213 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0266828 |
| JMJD1C | jumonji domain containing 1C | 0.0265583 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0264613 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0264514 |
| GOLGA4 | golgin A4 | 0.0264048 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0262438 |
| TMEM39A | transmembrane protein 39A | 0.0257326 |
| CD47 | CD47 molecule | 0.0250466 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0247203 |
| NUP58 | nucleoporin 58 | 0.024173 |
| SBF2 | SET binding factor 2 | 0.0235578 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0235288 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0232488 |
| CDC73 | cell division cycle 73 | 0.0231861 |
| SMYD3 | SET and MYND domain containing 3 | 0.0231294 |
| PDGFC | platelet derived growth factor C | 0.0230366 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.022893 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0224155 |
| RPL4 | ribosomal protein L4 | 0.0223846 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0223389 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0221915 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0220968 |
| GPHN | gephyrin | 0.0220092 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0219677 |
| EXOC6B | exocyst complex component 6B | 0.0219577 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0218917 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0216819 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0211809 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0211202 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0210908 |
| ANK2 | ankyrin 2, neuronal | 0.0209222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS8 | ribosomal protein S8 | -0.0904491 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0797905 |
| VIM | vimentin | -0.079387 |
| PTMA | prothymosin, alpha | -0.0777062 |
| RPS6 | ribosomal protein S6 | -0.074731 |
| RPL31 | ribosomal protein L31 | -0.0745947 |
| TMSB10 | thymosin beta 10 | -0.0544764 |
| NDRG1 | N-myc downstream regulated 1 | -0.0514699 |
| FTL | ferritin, light polypeptide | -0.0500882 |
| RPL35A | ribosomal protein L35a | -0.0487961 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0480404 |
| RPL37A | ribosomal protein L37a | -0.0477799 |
| RPL9 | ribosomal protein L9 | -0.0462647 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0450908 |
| RPS25 | ribosomal protein S25 | -0.0446289 |
| RPS3 | ribosomal protein S3 | -0.0425179 |
| RPS12 | ribosomal protein S12 | -0.0414157 |
| RPL7A | ribosomal protein L7a | -0.0403226 |
| RPS29 | ribosomal protein S29 | -0.0391886 |
| FN1 | fibronectin 1 | -0.0390777 |
| RPL19 | ribosomal protein L19 | -0.0371917 |
| RPS14 | ribosomal protein S14 | -0.0367072 |
| RPS19 | ribosomal protein S19 | -0.035785 |
| RPS10 | ribosomal protein S10 | -0.0354971 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0345398 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0344308 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0337138 |
| RPS13 | ribosomal protein S13 | -0.0335578 |
| HLA-B | major histocompatibility complex, class I, B | -0.0328343 |
| RPS27 | ribosomal protein S27 | -0.032683 |
| RPL37 | ribosomal protein L37 | -0.0316144 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0309073 |
| INTS6 | integrator complex subunit 6 | -0.0301364 |
| RPL23 | ribosomal protein L23 | -0.0300005 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0295818 |
| RPS23 | ribosomal protein S23 | -0.029344 |
| RPS27A | ribosomal protein S27a | -0.0292248 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.028729 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0280568 |
| PDE10A | phosphodiesterase 10A | -0.0278179 |
| RACK1 | receptor for activated C kinase 1 | -0.0267853 |
| RPL36A | ribosomal protein L36a | -0.0263685 |
| RPS20 | ribosomal protein S20 | -0.0262196 |
| RPLP2 | ribosomal protein, large, P2 | -0.0254965 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0254586 |
| RPS16 | ribosomal protein S16 | -0.0252575 |
| ASPH | aspartate beta-hydroxylase | -0.0250549 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0249985 |
| HM13 | histocompatibility (minor) 13 | -0.024654 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0244488 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0243764 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0239781 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0237519 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0236946 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.02336 |
| RPLP1 | ribosomal protein, large, P1 | -0.023273 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0232042 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0231064 |
| CD44 | CD44 molecule (Indian blood group) | -0.0230369 |
| AEBP2 | AE binding protein 2 | -0.0229074 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0228432 |
| STC1 | stanniocalcin 1 | -0.0227606 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0227109 |
| RPS2 | ribosomal protein S2 | -0.0227049 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0226588 |
| ITGA10 | integrin, alpha 10 | -0.0226175 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0225632 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0225307 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0224875 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.022342 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0222927 |
| IGF2 | insulin-like growth factor 2 | -0.0221886 |
| VEGFA | vascular endothelial growth factor A | -0.0219112 |
| RPS15 | ribosomal protein S15 | -0.0218668 |
| BMP10 | bone morphogenetic protein 10 | -0.021668 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0216197 |
| MED13L | mediator complex subunit 13-like | -0.0213223 |
| MTDH | metadherin | -0.0212943 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0210753 |
| POTEF | POTE ankyrin domain family, member F | -0.0210327 |
| S100A9 | S100 calcium binding protein A9 | -0.0206188 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0203929 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0202719 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0201213 |
| RPL38 | ribosomal protein L38 | -0.0200254 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0200067 |
| FBXO11 | F-box protein 11 | -0.0199886 |
| RPL15 | ribosomal protein L15 | -0.0197819 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0197001 |
| DENND4A | DENN/MADD domain containing 4A | -0.0196159 |
| LMO7 | LIM domain 7 | -0.0193627 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0188514 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0186802 |
| AREG | amphiregulin | -0.0185862 |
| ATG7 | autophagy related 7 | -0.0184618 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0183756 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0183506 |
| RPS17 | ribosomal protein S17 | -0.0182422 |
| RPL36 | ribosomal protein L36 | -0.0182337 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0181289 |
