| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.182187 |
| PDE10A | phosphodiesterase 10A | 0.153487 |
| FNDC3B | fibronectin type III domain containing 3B | 0.117317 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.109766 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0980488 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0917904 |
| KYNU | kynureninase | 0.0855126 |
| RPS6 | ribosomal protein S6 | 0.0772152 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0752798 |
| JMJD1C | jumonji domain containing 1C | 0.0740691 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0715109 |
| MT2A | metallothionein 2A | 0.0663843 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0640729 |
| ATP13A3 | ATPase type 13A3 | 0.0629064 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0601812 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0584417 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0559293 |
| CADM1 | cell adhesion molecule 1 | 0.0537948 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0512268 |
| HELZ | helicase with zinc finger | 0.0509048 |
| ADM | adrenomedullin | 0.0504689 |
| RPL35A | ribosomal protein L35a | 0.0481493 |
| SNX9 | sorting nexin 9 | 0.0468129 |
| RPL37A | ribosomal protein L37a | 0.0458006 |
| WTAP | Wilms tumor 1 associated protein | 0.0442467 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0434762 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0434225 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0429269 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0421607 |
| RPL9 | ribosomal protein L9 | 0.0417817 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0412426 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0393867 |
| SPAG9 | sperm associated antigen 9 | 0.0391391 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0387292 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.038042 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0379664 |
| FMNL2 | formin-like 2 | 0.0376029 |
| FOXO3 | forkhead box O3 | 0.0373489 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0367898 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0362255 |
| GLIS3 | GLIS family zinc finger 3 | 0.0360699 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0351456 |
| FRMD4A | FERM domain containing 4A | 0.0343761 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0332098 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0331842 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0331793 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0329868 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0327516 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.032365 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0318219 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0311138 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0310643 |
| MMP12 | matrix metallopeptidase 12 | 0.0309444 |
| SNX14 | sorting nexin 14 | 0.0301415 |
| RPL35 | ribosomal protein L35 | 0.0300783 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0296098 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0294322 |
| RPL19 | ribosomal protein L19 | 0.0293503 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0292082 |
| RPS21 | ribosomal protein S21 | 0.0286075 |
| RPL11 | ribosomal protein L11 | 0.0284352 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0282941 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0282266 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0278219 |
| TOP1 | topoisomerase (DNA) I | 0.0276554 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0275183 |
| DUSP5 | dual specificity phosphatase 5 | 0.0270563 |
| OGA | O-GlcNAcase | 0.0269027 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0268854 |
| PGK1 | phosphoglycerate kinase 1 | 0.0267532 |
| AFDN | afadin, adherens junction formation factor | 0.0265117 |
| PHIP | pleckstrin homology domain interacting protein | 0.026277 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0262596 |
| KLHL24 | kelch-like family member 24 | 0.0259075 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0259065 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0259017 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0257915 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0257191 |
| ACO1 | aconitase 1, soluble | 0.0256267 |
| SETD5 | SET domain containing 5 | 0.0255602 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0255542 |
| CAB39 | calcium binding protein 39 | 0.0254512 |
| KLF6 | Kruppel-like factor 6 | 0.0253335 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0252434 |
| NGLY1 | N-glycanase 1 | 0.0251906 |
| FNIP1 | folliculin interacting protein 1 | 0.0250755 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0248336 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0246648 |
| RPS14 | ribosomal protein S14 | 0.0242188 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0241347 |
| DENND5A | DENN/MADD domain containing 5A | 0.0235271 |
| PCBP3 | poly(rC) binding protein 3 | 0.0235083 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0234311 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0233085 |
| RNF24 | ring finger protein 24 | 0.0232431 |
| RASA2 | RAS p21 protein activator 2 | 0.0231417 |
| RPS13 | ribosomal protein S13 | 0.0231298 |
| TNPO1 | transportin 1 | 0.022743 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0226594 |
| NEK7 | NIMA-related kinase 7 | 0.0225766 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.22262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.170178 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.140859 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0900742 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0881305 |
| EGR1 | early growth response 1 | -0.0853806 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0840661 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0660516 |
| ENO1 | enolase 1, (alpha) | -0.0643296 |
| CALR | calreticulin | -0.0640084 |
| AHNAK | AHNAK nucleoprotein | -0.0634247 |
| VEGFA | vascular endothelial growth factor A | -0.0634124 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0632349 |
| TXNIP | thioredoxin interacting protein | -0.0578449 |
| LDHA | lactate dehydrogenase A | -0.05336 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0508684 |
| NDRG1 | N-myc downstream regulated 1 | -0.0508372 |
| SFTPA2 | surfactant protein A2 | -0.050208 |
| YBX1 | Y box binding protein 1 | -0.0496703 |
| TAPBP | TAP binding protein (tapasin) | -0.048651 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0452388 |
| MSN | moesin | -0.0451792 |
| SQSTM1 | sequestosome 1 | -0.0451111 |
| JUN | jun proto-oncogene | -0.0448229 |
| FLNA | filamin A, alpha | -0.0434265 |
| CANX | calnexin | -0.04267 |
| VMP1 | vacuole membrane protein 1 | -0.0423433 |
| VIM | vimentin | -0.0403291 |
| UBC | ubiquitin C | -0.0391015 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0378055 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0371355 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0369423 |
| CD44 | CD44 molecule (Indian blood group) | -0.0367502 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0365502 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0361824 |
| ASPH | aspartate beta-hydroxylase | -0.0361505 |
| VCL | vinculin | -0.0357116 |
| THBS1 | thrombospondin 1 | -0.0354337 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0354017 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0349859 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0348373 |
| MAP1B | microtubule-associated protein 1B | -0.0345493 |
| CTSD | cathepsin D | -0.034281 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.033907 |
| RPS2 | ribosomal protein S2 | -0.0335778 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0332936 |
| C3 | complement component 3 | -0.0331107 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.032985 |
| TPM4 | tropomyosin 4 | -0.0328206 |
| OPTN | optineurin | -0.0327759 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0325415 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0323368 |
| COL1A2 | collagen, type I, alpha 2 | -0.031894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0318116 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0315017 |
| FTL | ferritin, light polypeptide | -0.0310369 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309955 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0308503 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0293547 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0288332 |
| HDLBP | high density lipoprotein binding protein | -0.0287135 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0282251 |
| POTEF | POTE ankyrin domain family, member F | -0.0281575 |
| NONO | non-POU domain containing, octamer-binding | -0.0276216 |
| CTSA | cathepsin A | -0.0266866 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026594 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0264108 |
| ARF4 | ADP-ribosylation factor 4 | -0.025975 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0259497 |
| ANXA2 | annexin A2 | -0.0253028 |
| VCAN | versican | -0.0250993 |
| TPM1 | tropomyosin 1 (alpha) | -0.0250936 |
| MX1 | MX dynamin-like GTPase 1 | -0.0250778 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0250598 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0245874 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0244198 |
| MCL1 | myeloid cell leukemia 1 | -0.0237324 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0234774 |
| HLA-E | major histocompatibility complex, class I, E | -0.023408 |
| RNF213 | ring finger protein 213 | -0.0233999 |
| PKM | pyruvate kinase, muscle | -0.0232694 |
| CLIC4 | chloride intracellular channel 4 | -0.0229218 |
| TFG | TRK-fused gene | -0.022905 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0226766 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0225443 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0225012 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0224082 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0222233 |
| APP | amyloid beta (A4) precursor protein | -0.0221738 |
| BSG | basigin (Ok blood group) | -0.0220605 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0220438 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0219197 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0217044 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0214052 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.021365 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0210344 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0207465 |
| WASF2 | WAS protein family, member 2 | -0.0207273 |
| VDAC1 | voltage-dependent anion channel 1 | -0.020641 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.020636 |
