| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.232904 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.129327 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.127158 |
| TMSB10 | thymosin beta 10 | 0.0890921 |
| MT1X | metallothionein 1X | 0.0838757 |
| B2M | beta-2-microglobulin | 0.0786928 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0685115 |
| STC1 | stanniocalcin 1 | 0.0650082 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0620508 |
| ATP13A3 | ATPase type 13A3 | 0.0618926 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0610237 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0597185 |
| NDRG1 | N-myc downstream regulated 1 | 0.0526283 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.052141 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0484514 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0480926 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0409854 |
| FTL | ferritin, light polypeptide | 0.0404432 |
| FAM13A | family with sequence similarity 13, member A | 0.0380104 |
| CCNI | cyclin I | 0.0375012 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0359043 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0357145 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0355344 |
| ZNF395 | zinc finger protein 395 | 0.0354768 |
| ADM | adrenomedullin | 0.0352959 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0346142 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0332446 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.032489 |
| ARRDC3 | arrestin domain containing 3 | 0.0312749 |
| RPS21 | ribosomal protein S21 | 0.0304578 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0300379 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0299286 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0296437 |
| PTN | pleiotrophin | 0.0296182 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0292929 |
| CDK7 | cyclin-dependent kinase 7 | 0.0292549 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0285589 |
| SDC4 | syndecan 4 | 0.0284465 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0284303 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0281018 |
| ZNF292 | zinc finger protein 292 | 0.0279046 |
| IGF2 | insulin-like growth factor 2 | 0.0276308 |
| S100A10 | S100 calcium binding protein A10 | 0.0273214 |
| LOC112694756 | uncharaterized LOC112694756 | 0.027176 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0266519 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0266012 |
| IKBIP | IKBKB interacting protein | 0.0261831 |
| SUCO | SUN domain containing ossification factor | 0.0255069 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0252575 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0251666 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0251508 |
| RASA2 | RAS p21 protein activator 2 | 0.025046 |
| RPL28 | ribosomal protein L28 | 0.0249195 |
| RLF | rearranged L-myc fusion | 0.0248625 |
| RNF145 | ring finger protein 145 | 0.0248425 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0247043 |
| RNF24 | ring finger protein 24 | 0.0246908 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0244538 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0235408 |
| WDR26 | WD repeat domain 26 | 0.023481 |
| USP3 | ubiquitin specific peptidase 3 | 0.0234449 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0231343 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0230705 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0230621 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0230482 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0229818 |
| UBC | ubiquitin C | 0.0228367 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0227517 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0227328 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0226896 |
| RTN4 | reticulon 4 | 0.0221478 |
| COG6 | component of oligomeric golgi complex 6 | 0.0218287 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0216243 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.021591 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0215859 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.021538 |
| RPL23 | ribosomal protein L23 | 0.0214476 |
| S100A6 | S100 calcium binding protein A6 | 0.0211824 |
| MED10 | mediator complex subunit 10 | 0.0210113 |
| CD109 | CD109 molecule | 0.0210108 |
| H3-3B | H3.3 histone B | 0.0209371 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.020648 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.020644 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0204638 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0203625 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0202507 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0200283 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0199295 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0197829 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0197684 |
| FRMD6 | FERM domain containing 6 | 0.0197048 |
| SNX9 | sorting nexin 9 | 0.0196951 |
| UPP1 | uridine phosphorylase 1 | 0.0195817 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0193516 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0192914 |
| TMED4 | transmembrane emp24 protein transport domain containing 4 | 0.0189857 |
| ACTN1 | actinin, alpha 1 | 0.0188823 |
| CFDP1 | craniofacial development protein 1 | 0.0187213 |
| HOMER2 | homer scaffolding protein 2 | 0.0185914 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0184907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.362736 |
| FN1 | fibronectin 1 | -0.244685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156881 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.152006 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.142225 |
| CDH13 | cadherin 13 | -0.0919733 |
| POTEF | POTE ankyrin domain family, member F | -0.0720565 |
| ENO1 | enolase 1, (alpha) | -0.070707 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0698593 |
| CALD1 | caldesmon 1 | -0.0686326 |
| VCL | vinculin | -0.0680373 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0655855 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0588815 |
| LOX | lysyl oxidase | -0.0579352 |
| ACTG1 | actin gamma 1 | -0.0546479 |
| TNS3 | tensin 3 | -0.0508849 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0500238 |
| MAP1B | microtubule-associated protein 1B | -0.049485 |
| TPM4 | tropomyosin 4 | -0.0490126 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0488986 |
| RAI14 | retinoic acid induced 14 | -0.0481584 |
| GLIS3 | GLIS family zinc finger 3 | -0.0475869 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0472302 |
| NAV1 | neuron navigator 1 | -0.0471094 |
| COL5A1 | collagen, type V, alpha 1 | -0.0464192 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0462591 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0455994 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0452944 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0421591 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0414029 |
| EGFR | epidermal growth factor receptor | -0.0400145 |
| IL6 | interleukin 6 | -0.0399446 |
| MAP4 | microtubule-associated protein 4 | -0.0398996 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0383556 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0379448 |
| RRBP1 | ribosome binding protein 1 | -0.0374035 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.037076 |
| CDK13 | cyclin-dependent kinase 13 | -0.0368806 |
| SEPTIN7 | septin 7 | -0.0365972 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0362322 |
| COL1A1 | collagen, type I, alpha 1 | -0.036007 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0359017 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0355784 |
| UTRN | utrophin | -0.0354503 |
| KAZN | kazrin, periplakin interacting protein | -0.0350442 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347441 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.034022 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0339349 |
| CANX | calnexin | -0.0331007 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0320413 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0317172 |
| CLIC4 | chloride intracellular channel 4 | -0.0309594 |
| TPM1 | tropomyosin 1 (alpha) | -0.0309391 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | -0.030764 |
| AHNAK | AHNAK nucleoprotein | -0.0307307 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.030643 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0305211 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0303704 |
| PTMA | prothymosin, alpha | -0.0298788 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0297538 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0297404 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0297118 |
| FRMD4A | FERM domain containing 4A | -0.0296168 |
| LSAMP | limbic system-associated membrane protein | -0.0294035 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0290916 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0286315 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0285323 |
| SBF2 | SET binding factor 2 | -0.0276608 |
| IL6ST | interleukin 6 signal transducer | -0.0273844 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0272972 |
| CDK6 | cyclin-dependent kinase 6 | -0.0271837 |
| PTK2 | protein tyrosine kinase 2 | -0.0271596 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0269036 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0267987 |
| PRKCA | protein kinase C, alpha | -0.0265973 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0265869 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0265574 |
| CEP350 | centrosomal protein 350kDa | -0.0261591 |
| MXI1 | MAX interactor 1, dimerization protein | -0.025775 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0257087 |
| ATG7 | autophagy related 7 | -0.0248643 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0247563 |
| CALR | calreticulin | -0.0246958 |
| KYNU | kynureninase | -0.0244358 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0243976 |
| CALU | calumenin | -0.0241736 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.024061 |
| AAK1 | AP2 associated kinase 1 | -0.0240199 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0239973 |
| NBEAL1 | neurobeachin-like 1 | -0.023863 |
| ASPH | aspartate beta-hydroxylase | -0.0237617 |
| NABP1 | nucleic acid binding protein 1 | -0.0234987 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.023063 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0229111 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0229017 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0227906 |
| NRP1 | neuropilin 1 | -0.022719 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.022182 |
| HM13 | histocompatibility (minor) 13 | -0.0221453 |
| DST | dystonin | -0.0219914 |
