| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WAC | WW domain containing adaptor with coiled-coil | 0.124364 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.076795 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0726173 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0682459 |
| DNER | delta/notch-like EGF repeat containing | 0.0682068 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0640486 |
| GOLGA4 | golgin A4 | 0.0618024 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0581464 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0530006 |
| LDHA | lactate dehydrogenase A | 0.0506396 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0501264 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.049733 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0495193 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0489491 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0482421 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0474949 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0465639 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0458214 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0445615 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.043782 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0435708 |
| RB1 | retinoblastoma 1 | 0.0432215 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.042878 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0421195 |
| ECT2 | epithelial cell transforming 2 | 0.0420226 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0411455 |
| ATP13A3 | ATPase type 13A3 | 0.0409793 |
| SMAD3 | SMAD family member 3 | 0.0408466 |
| SEC24A | SEC24 family member A | 0.0400922 |
| PDE8A | phosphodiesterase 8A | 0.0400816 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0397457 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0393307 |
| TPI1 | triosephosphate isomerase 1 | 0.0390618 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0382499 |
| CD44 | CD44 molecule (Indian blood group) | 0.0378985 |
| YBX3 | Y box binding protein 3 | 0.0378437 |
| NUP58 | nucleoporin 58 | 0.0373298 |
| ZNF638 | zinc finger protein 638 | 0.0370146 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0361694 |
| KIAA1328 | KIAA1328 | 0.0360882 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0360296 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0357173 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0354701 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0354235 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0352707 |
| RSF1 | remodeling and spacing factor 1 | 0.0351976 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.034703 |
| ATRN | attractin | 0.0346023 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0345112 |
| CFH | complement factor H | 0.0340908 |
| FNIP1 | folliculin interacting protein 1 | 0.0334767 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0331646 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0329146 |
| DIAPH3 | diaphanous-related formin 3 | 0.0326307 |
| KIAA1958 | KIAA1958 | 0.032546 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0325399 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0324187 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0315667 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.0311831 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0309369 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0307505 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0303052 |
| UBE3C | ubiquitin protein ligase E3C | 0.0299103 |
| RASA2 | RAS p21 protein activator 2 | 0.0298314 |
| RDX | radixin | 0.0295436 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0291646 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0290662 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0289644 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0289086 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0286562 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0283846 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0283825 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0283414 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.028181 |
| ATG7 | autophagy related 7 | 0.0281019 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 0.02808 |
| RAB10 | RAB10, member RAS oncogene family | 0.0280586 |
| CAPRIN2 | caprin family member 2 | 0.0279048 |
| IPO8 | importin 8 | 0.0278603 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0278324 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.027686 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0273863 |
| GNAS | GNAS complex locus | 0.0272738 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0272723 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0272214 |
| RBM39 | RNA binding motif protein 39 | 0.0271965 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0270835 |
| MORF4L2 | mortality factor 4 like 2 | 0.0269637 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | 0.026882 |
| UBQLN1 | ubiquilin 1 | 0.0268552 |
| MATR3 | matrin 3 | 0.0266762 |
| TOP1 | topoisomerase (DNA) I | 0.026544 |
| CCNH | cyclin H | 0.0264759 |
| HDAC9 | histone deacetylase 9 | 0.026332 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0262134 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0261876 |
| RTN3 | reticulon 3 | 0.026103 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0259462 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0258043 |
| WBP11 | WW domain binding protein 11 | 0.025762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.11535 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102586 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0706637 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0665404 |
| MT2A | metallothionein 2A | -0.0659583 |
| POTEF | POTE ankyrin domain family, member F | -0.0599792 |
| SVIL | supervillin | -0.0580741 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.056304 |
| EGFR | epidermal growth factor receptor | -0.055541 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0544249 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0543637 |
| NDRG1 | N-myc downstream regulated 1 | -0.0539393 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0513838 |
| VCL | vinculin | -0.0501843 |
| TMEM123 | transmembrane protein 123 | -0.0497665 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0485249 |
| TMSB10 | thymosin beta 10 | -0.0479835 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0476941 |
| PFN1 | profilin 1 | -0.0471677 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0460291 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0453542 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0446209 |
| RPLP1 | ribosomal protein, large, P1 | -0.0432395 |
| RPS3 | ribosomal protein S3 | -0.0424328 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0417241 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0399031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0394711 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.038887 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0387887 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0386827 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.038646 |
| TAOK1 | TAO kinase 1 | -0.0384638 |
| SP100 | SP100 nuclear antigen | -0.0381012 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0380659 |
| ITGAV | integrin, alpha V | -0.0369999 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0368907 |
| ASPH | aspartate beta-hydroxylase | -0.0368489 |
| ABR | active BCR-related | -0.0358858 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0356867 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0356362 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0355298 |
| AHNAK | AHNAK nucleoprotein | -0.0352956 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0351987 |
| SLC38A2 | solute carrier family 38, member 2 | -0.034795 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343754 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0342246 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0333936 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0333796 |
| TCF12 | transcription factor 12 | -0.0331847 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0331777 |
| CALR | calreticulin | -0.033118 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0330516 |
| TPM4 | tropomyosin 4 | -0.0329374 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0324243 |
| PDE10A | phosphodiesterase 10A | -0.0322784 |
| RORA | RAR-related orphan receptor A | -0.0320452 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0316932 |
| ITGA6 | integrin, alpha 6 | -0.0313605 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0311907 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0311702 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0309698 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0309229 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0306508 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0305965 |
| RIN2 | Ras and Rab interactor 2 | -0.0302025 |
| SBF2 | SET binding factor 2 | -0.0300846 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0300648 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0300157 |
| FN1 | fibronectin 1 | -0.02991 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0298068 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0295776 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0293964 |
| TES | testin LIM domain protein | -0.0292629 |
| ERBIN | erbb2 interacting protein | -0.0291721 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0290772 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.028781 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0286742 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.028536 |
| HLA-A | major histocompatibility complex, class I, A | -0.0284728 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0284427 |
| SKIL | SKI-like proto-oncogene | -0.0284252 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0284 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0283858 |
| DEK | DEK proto-oncogene | -0.0283656 |
| ANXA2 | annexin A2 | -0.0279192 |
| HELZ | helicase with zinc finger | -0.0279041 |
| HMGA2 | high mobility group AT-hook 2 | -0.0278147 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0277784 |
| PTK2 | protein tyrosine kinase 2 | -0.0277005 |
| RPLP2 | ribosomal protein, large, P2 | -0.0276081 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.027589 |
| RLIM | ring finger protein, LIM domain interacting | -0.0275186 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0274821 |
| NBEA | neurobeachin | -0.0271522 |
| SDC4 | syndecan 4 | -0.0270409 |
| MYOF | myoferlin | -0.0269217 |
| CCND1 | cyclin D1 | -0.0268626 |
| BCL9L | B-cell CLL/lymphoma 9-like | -0.0268491 |
| PRKCA | protein kinase C, alpha | -0.0268354 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0267985 |
