| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.130336 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0747643 |
| ITGA1 | integrin, alpha 1 | 0.0715195 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0591775 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0517915 |
| CD109 | CD109 molecule | 0.0469006 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0458649 |
| DENND5B | DENN/MADD domain containing 5B | 0.0430337 |
| RNF145 | ring finger protein 145 | 0.0401598 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0400105 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0385245 |
| GOLGA4 | golgin A4 | 0.0376373 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0369872 |
| COG5 | component of oligomeric golgi complex 5 | 0.0354628 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0348759 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0348508 |
| HELZ | helicase with zinc finger | 0.0334667 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0331283 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0323402 |
| OGA | O-GlcNAcase | 0.0323297 |
| SRP54 | signal recognition particle 54kDa | 0.0320736 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0318294 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0315901 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0314612 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.030578 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0305668 |
| NUP58 | nucleoporin 58 | 0.0305581 |
| PELO | pelota homolog (Drosophila) | 0.0302754 |
| TPR | translocated promoter region, nuclear basket protein | 0.0301643 |
| SPAG9 | sperm associated antigen 9 | 0.0282025 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0265954 |
| CDC27 | cell division cycle 27 | 0.0265606 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0264533 |
| SETD5 | SET domain containing 5 | 0.0261983 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0261019 |
| SUCO | SUN domain containing ossification factor | 0.0260702 |
| FOXO3 | forkhead box O3 | 0.0260432 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0259998 |
| NEK7 | NIMA-related kinase 7 | 0.0259538 |
| PUM2 | pumilio RNA-binding family member 2 | 0.02535 |
| TMEM165 | transmembrane protein 165 | 0.0251219 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0249536 |
| WDR45B | WD repeat domain 45B | 0.0244598 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0243946 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0243718 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0240311 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0238994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0238765 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0237781 |
| CTBP2 | C-terminal binding protein 2 | 0.0229074 |
| ETNK1 | ethanolamine kinase 1 | 0.0228118 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0227077 |
| CAB39 | calcium binding protein 39 | 0.0226783 |
| SEC24A | SEC24 family member A | 0.0225852 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0225739 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0222073 |
| FOXJ3 | forkhead box J3 | 0.0220989 |
| SFXN1 | sideroflexin 1 | 0.02182 |
| RPS6 | ribosomal protein S6 | 0.0216222 |
| MT2A | metallothionein 2A | 0.0215377 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0212688 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0212571 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0211158 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.020733 |
| WDR43 | WD repeat domain 43 | 0.0207086 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0206841 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0206278 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0206134 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0203493 |
| CDC73 | cell division cycle 73 | 0.0203135 |
| RBM25 | RNA binding motif protein 25 | 0.0201103 |
| ATP13A3 | ATPase type 13A3 | 0.0198552 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0198256 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0197932 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0195616 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0194997 |
| INSIG2 | insulin induced gene 2 | 0.0194565 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0192683 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0190888 |
| SIK3 | SIK family kinase 3 | 0.0188769 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0187586 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0186877 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0185301 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0183752 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0183584 |
| RPL37A | ribosomal protein L37a | 0.0182598 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0179198 |
| FRYL | FRY-like | 0.0177659 |
| SNX13 | sorting nexin 13 | 0.0176989 |
| RPS16 | ribosomal protein S16 | 0.0176457 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0175215 |
| NBAS | neuroblastoma amplified sequence | 0.0173578 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0172093 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0171818 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0169015 |
| PCBP2 | poly(rC) binding protein 2 | 0.0168339 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0168215 |
| GOLT1B | golgi transport 1B | 0.0168128 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0167069 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0166928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.253946 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.240338 |
| NRG1 | neuregulin 1 | -0.146845 |
| ASPH | aspartate beta-hydroxylase | -0.133145 |
| NDRG1 | N-myc downstream regulated 1 | -0.0956706 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0924149 |
| VCL | vinculin | -0.0815526 |
| HMGA2 | high mobility group AT-hook 2 | -0.0706869 |
| SQSTM1 | sequestosome 1 | -0.0647748 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0588753 |
| MAP1B | microtubule-associated protein 1B | -0.0587959 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0572289 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.054979 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0538928 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0530214 |
| POTEF | POTE ankyrin domain family, member F | -0.0514977 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0489506 |
| EGR1 | early growth response 1 | -0.0486362 |
| TXNIP | thioredoxin interacting protein | -0.048053 |
| ACTG1 | actin gamma 1 | -0.0477193 |
| TMSB10 | thymosin beta 10 | -0.0475081 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0466461 |
| SYT1 | synaptotagmin I | -0.046518 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0449934 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.044559 |
| VEGFA | vascular endothelial growth factor A | -0.0426551 |
| HLA-B | major histocompatibility complex, class I, B | -0.0413053 |
| PTMA | prothymosin, alpha | -0.0410843 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0402336 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0397569 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0380269 |
| TMSB4X | thymosin beta 4, X-linked | -0.0363566 |
| NTN4 | netrin 4 | -0.0361764 |
| ENO1 | enolase 1, (alpha) | -0.0359541 |
| CANX | calnexin | -0.0353509 |
| MCL1 | myeloid cell leukemia 1 | -0.0349782 |
| RNF213 | ring finger protein 213 | -0.0348371 |
| S100A6 | S100 calcium binding protein A6 | -0.0341684 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.033875 |
| ACTN4 | actinin, alpha 4 | -0.0338223 |
| TNNC1 | troponin C type 1 (slow) | -0.0337376 |
| PALLD | palladin, cytoskeletal associated protein | -0.0336576 |
| ETV1 | ets variant 1 | -0.0334678 |
| LMNA | lamin A/C | -0.0331409 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0328467 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0327786 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.03273 |
| VIM | vimentin | -0.0322499 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0321063 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0318541 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0318532 |
| HMGA1 | high mobility group AT-hook 1 | -0.0315111 |
| FTL | ferritin, light polypeptide | -0.0311171 |
| STC2 | stanniocalcin 2 | -0.0309687 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.030525 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0303914 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0300052 |
| JUN | jun proto-oncogene | -0.0293013 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.029191 |
| AHNAK | AHNAK nucleoprotein | -0.0290278 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.028976 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0285939 |
| LOXL2 | lysyl oxidase-like 2 | -0.0276551 |
| GLIS3 | GLIS family zinc finger 3 | -0.0265365 |
| PLIN2 | perilipin 2 | -0.0265319 |
| TPM4 | tropomyosin 4 | -0.0262528 |
| DST | dystonin | -0.0259224 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0258323 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0256044 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0251707 |
| GLUL | glutamate-ammonia ligase | -0.0249906 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0249592 |
| TAGLN2 | transgelin 2 | -0.0249051 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0247847 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0247465 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0246934 |
| FLNA | filamin A, alpha | -0.0246484 |
| SFTPA2 | surfactant protein A2 | -0.0245949 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0244611 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.024291 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0240637 |
| RRBP1 | ribosome binding protein 1 | -0.0239841 |
| S100A10 | S100 calcium binding protein A10 | -0.0237391 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0235287 |
| H1-0 | H1.0 linker histone | -0.0233488 |
| TMEM156 | transmembrane protein 156 | -0.022911 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0226845 |
| TGFB1 | transforming growth factor, beta 1 | -0.0225375 |
| CENPF | centromere protein F, 350/400kDa | -0.0224969 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.022476 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0221919 |
| NAV1 | neuron navigator 1 | -0.0221219 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.0221071 |
| WDR1 | WD repeat domain 1 | -0.0218663 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0218574 |
| CD44 | CD44 molecule (Indian blood group) | -0.0216599 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0215119 |
| MKI67 | marker of proliferation Ki-67 | -0.0214318 |
| AEBP2 | AE binding protein 2 | -0.0214053 |
| BSG | basigin (Ok blood group) | -0.0212759 |
