Rapamycin vs Ctrl Exp2 MEFs (Mouse) [21659605] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs
Category proteomics
Type drug perturbation
Description drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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Genes

103 proteins differentially phosphorylated following the Rapamycin vs Ctrl Exp2 MEFs (Mouse) [21659605] drug perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

increased phosphorylation

Symbol Name

decreased phosphorylation

Symbol Name
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
AHNAK2 AHNAK nucleoprotein 2
AIM1 absent in melanoma 1
ANKRD34B ankyrin repeat domain 34B
ANKRD50 ankyrin repeat domain 50
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLF aprataxin and PNKP like factor
ARHGAP28 Rho GTPase activating protein 28
ARHGAP44 Rho GTPase activating protein 44
ARL14EP ADP-ribosylation factor-like 14 effector protein
BCL10 B-cell CLL/lymphoma 10
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C11ORF84 chromosome 11 open reading frame 84
C15ORF39 chromosome 15 open reading frame 39
C17ORF59 chromosome 17 open reading frame 59
C1ORF35 chromosome 1 open reading frame 35
CAMLG calcium modulating ligand
CCDC105 coiled-coil domain containing 105
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLDN15 claudin 15
COG3 component of oligomeric golgi complex 3
COMT catechol-O-methyltransferase
CPSF3L cleavage and polyadenylation specific factor 3-like
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
DNAAF1 dynein, axonemal, assembly factor 1
DVL3 dishevelled segment polarity protein 3
ERRFI1 ERBB receptor feedback inhibitor 1
EXOC7 exocyst complex component 7
FAM8A1 family with sequence similarity 8, member A1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FLT4 fms-related tyrosine kinase 4
FOXD4 forkhead box D4
FOXP1 forkhead box P1
GLB1L galactosidase, beta 1-like
HSPA12B heat shock 70kD protein 12B
IER3 immediate early response 3
IGHMBP2 immunoglobulin mu binding protein 2
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INVS inversin
IRF3 interferon regulatory factor 3
KARS lysyl-tRNA synthetase
KIF1A kinesin family member 1A
KLHL25 kelch-like family member 25
LCA5 Leber congenital amaurosis 5
LIMK1 LIM domain kinase 1
LSP1 lymphocyte-specific protein 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAPK7 mitogen-activated protein kinase 7
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MAST3 microtubule associated serine/threonine kinase 3
MAST4 microtubule associated serine/threonine kinase family member 4
MCM9 minichromosome maintenance complex component 9
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTSS1 metastasis suppressor 1
MYOD1 myogenic differentiation 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NISCH nischarin
PANK1 pantothenate kinase 1
PBX1 pre-B-cell leukemia homeobox 1
PDLIM4 PDZ and LIM domain 4
PLCB4 phospholipase C, beta 4
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PRR5 proline rich 5 (renal)
PTOV1 prostate tumor overexpressed 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RBSN rabenosyn, RAB effector
REEP2 receptor accessory protein 2
RGS3 regulator of G-protein signaling 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIN2 Ras and Rab interactor 2
SEC24D SEC24 family member D
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPT7 septin 7
SEPT9 septin 9
SHROOM4 shroom family member 4
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SMTNL2 smoothelin-like 2
SNX8 sorting nexin 8
SPATA13 spermatogenesis associated 13
SPATA6 spermatogenesis associated 6
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK11 serine/threonine kinase 11
SWI5 SWI5 recombination repair homolog (yeast)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TARS threonyl-tRNA synthetase
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TFE3 transcription factor binding to IGHM enhancer 3
TRAPPC10 trafficking protein particle complex 10
TTC7B tetratricopeptide repeat domain 7B
UBXN1 UBX domain protein 1
UGDH UDP-glucose 6-dehydrogenase
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VCP valosin containing protein
VSX1 visual system homeobox 1
WDR24 WD repeat domain 24
WT1 Wilms tumor 1
WWC2 WW and C2 domain containing 2
ZFPM2 zinc finger protein, FOG family member 2
ZHX2 zinc fingers and homeoboxes 2
ZNF516 zinc finger protein 516
ZNF521 zinc finger protein 521