Rapamycin vs Ctrl_Exp1_MEFs (Mouse) [21659605] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs
Category proteomics
Type drug perturbation
Description drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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Genes

888 proteins differentially phosphorylated following the Rapamycin vs Ctrl_Exp1_MEFs (Mouse) [21659605] drug perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

increased phosphorylation

Symbol Name
AAK1 AP2 associated kinase 1
AARSD1 alanyl-tRNA synthetase domain containing 1
AATF apoptosis antagonizing transcription factor
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABLIM1 actin binding LIM protein 1
ACBD5 acyl-CoA binding domain containing 5
ACIN1 apoptotic chromatin condensation inducer 1
ADD1 adducin 1 (alpha)
ADD3 adducin 3 (gamma)
AEBP2 AE binding protein 2
AFAP1 actin filament associated protein 1
AGO2 argonaute RISC catalytic component 2
AHCTF1 AT hook containing transcription factor 1
AHNAK AHNAK nucleoprotein
AJUBA ajuba LIM protein
AKAP12 A kinase (PRKA) anchor protein 12
AKAP8 A kinase (PRKA) anchor protein 8
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKTIP AKT interacting protein
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMPD2 adenosine monophosphate deaminase 2
ANKK1 ankyrin repeat and kinase domain containing 1
ANKRD17 ankyrin repeat domain 17
ANLN anillin, actin binding protein
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APC adenomatous polyposis coli
API5 apoptosis inhibitor 5
APLF aprataxin and PNKP like factor
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP12 Rho GTPase activating protein 12
ARHGAP18 Rho GTPase activating protein 18
ARHGAP21 Rho GTPase activating protein 21
ARHGAP28 Rho GTPase activating protein 28
ARHGAP31 Rho GTPase activating protein 31
ARHGAP5 Rho GTPase activating protein 5
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID1A AT rich interactive domain 1A (SWI-like)
ARMC10 armadillo repeat containing 10
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATE1 arginyltransferase 1
ATF2 activating transcription factor 2
ATF7IP activating transcription factor 7 interacting protein
ATG2B autophagy related 2B
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN2 ataxin 2
ATXN2L ataxin 2-like
AVEN apoptosis, caspase activation inhibitor
BAG3 BCL2-associated athanogene 3
BAG6 BCL2-associated athanogene 6
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCLAF1 BCL2-associated transcription factor 1
BIN1 bridging integrator 1
BIRC6 baculoviral IAP repeat containing 6
BMP2K BMP2 inducible kinase
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BOP1 block of proliferation 1
BRD3 bromodomain containing 3
BRWD1 bromodomain and WD repeat domain containing 1
BYSL bystin-like
BZW2 basic leucine zipper and W2 domains 2
C11ORF58 chromosome 11 open reading frame 58
C17ORF49 chromosome 17 open reading frame 49
C17ORF59 chromosome 17 open reading frame 59
C17ORF75 chromosome 17 open reading frame 75
C1ORF198 chromosome 1 open reading frame 198
C2ORF49 chromosome 2 open reading frame 49
C9ORF114 chromosome 9 open reading frame 114
C9ORF78 chromosome 9 open reading frame 78
CAAP1 caspase activity and apoptosis inhibitor 1
CACTIN cactin, spliceosome C complex subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASC3 cancer susceptibility candidate 3
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAST calpastatin
CBX4 chromobox homolog 4
CBX5 chromobox homolog 5
CBY1 chibby homolog 1 (Drosophila)
CCAR2 cell cycle and apoptosis regulator 2
CCDC43 coiled-coil domain containing 43
CCDC6 coiled-coil domain containing 6
CCDC86 coiled-coil domain containing 86
CCDC88A coiled-coil domain containing 88A
CCNL1 cyclin L1
CD2AP CD2-associated protein
CD34 CD34 molecule
CDC23 cell division cycle 23
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK11B cyclin-dependent kinase 11B
CDK13 cyclin-dependent kinase 13
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDR2L cerebellar degeneration-related protein 2-like
CDYL chromodomain protein, Y-like
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEP170 centrosomal protein 170kDa
CEP350 centrosomal protein 350kDa
CEP55 centrosomal protein 55kDa
CFAP97 cilia and flagella associated protein 97
CFL1 cofilin 1 (non-muscle)
CGN cingulin
CGNL1 cingulin-like 1
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD2 chromodomain helicase DNA binding protein 2
CHD4 chromodomain helicase DNA binding protein 4
CHD8 chromodomain helicase DNA binding protein 8
CHD9 chromodomain helicase DNA binding protein 9
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CIC capicua transcriptional repressor
CIR1 corepressor interacting with RBPJ, 1
CLASP1 cytoplasmic linker associated protein 1
CLDN12 claudin 12
CLIP1 CAP-GLY domain containing linker protein 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
CMTR1 cap methyltransferase 1
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CNOT4 CCR4-NOT transcription complex, subunit 4
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CR1L complement component (3b/4b) receptor 1-like
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTPS1 CTP synthase 1
CTPS2 CTP synthase 2
CTTN cortactin
CUL4B cullin 4B
CUX1 cut-like homeobox 1
CXORF23 chromosome X open reading frame 23
DACT3 dishevelled-binding antagonist of beta-catenin 3
DBN1 drebrin 1
DBNL drebrin-like
DCAF5 DDB1 and CUL4 associated factor 5
DCAF8 DDB1 and CUL4 associated factor 8
DCLRE1C DNA cross-link repair 1C
DCP1A decapping mRNA 1A
DDIT3 DNA-damage-inducible transcript 3
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
DEK DEK proto-oncogene
DENND2A DENN/MADD domain containing 2A
DENND4C DENN/MADD domain containing 4C
DES desmin
DGCR8 DGCR8 microprocessor complex subunit
DIDO1 death inducer-obliterator 1
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DKC1 dyskeratosis congenita 1, dyskerin
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
DNM2 dynamin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK7 dedicator of cytokinesis 7
DPF2 D4, zinc and double PHD fingers family 2
DPYSL2 dihydropyrimidinase-like 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EAPP E2F-associated phosphoprotein
EBAG9 estrogen receptor binding site associated, antigen, 9
EDC4 enhancer of mRNA decapping 4
EED embryonic ectoderm development
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EHBP1 EH domain binding protein 1
EHBP1L1 EH domain binding protein 1-like 1
EHD2 EH-domain containing 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5 eukaryotic translation initiation factor 5
EIF5B eukaryotic translation initiation factor 5B
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EP400 E1A binding protein p400
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPHB2 EPH receptor B2
EPN2 epsin 2
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2IP erbb2 interacting protein
ERCC6L excision repair cross-complementation group 6-like
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESYT2 extended synaptotagmin-like protein 2
ETV6 ets variant 6
EVL Enah/Vasp-like
EXOC1 exocyst complex component 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11R F11 receptor
FAM110B family with sequence similarity 110, member B
FAM117B family with sequence similarity 117, member B
FAM122A family with sequence similarity 122A
FAM129A family with sequence similarity 129, member A
FAM129B family with sequence similarity 129, member B
FAM134A family with sequence similarity 134, member A
FAM134C family with sequence similarity 134, member C
FAM175B family with sequence similarity 175, member B
FAM64A family with sequence similarity 64, member A
FAM65A family with sequence similarity 65, member A
FAM83H family with sequence similarity 83, member H
FAN1 FANCD2/FANCI-associated nuclease 1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXO38 F-box protein 38
FCHO2 FCH domain only 2
FERMT2 fermitin family member 2
FIP1L1 factor interacting with PAPOLA and CPSF1
FKBP15 FK506 binding protein 15, 133kDa
FLNC filamin C, gamma
FMNL3 formin-like 3
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FNBP1L formin binding protein 1-like
FNBP4 formin binding protein 4
FOSL2 FOS-like antigen 2
FOXK1 forkhead box K1
FOXK2 forkhead box K2
FRMD4B FERM domain containing 4B
FTSJ3 FtsJ homolog 3 (E. coli)
FXR1 fragile X mental retardation, autosomal homolog 1
FXR2 fragile X mental retardation, autosomal homolog 2
FYTTD1 forty-two-three domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB1 GRB2-associated binding protein 1
GAS2L1 growth arrest-specific 2 like 1
GATAD2A GATA zinc finger domain containing 2A
GATAD2B GATA zinc finger domain containing 2B
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
GIGYF2 GRB10 interacting GYF protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLI3 GLI family zinc finger 3
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLGA5 golgin A5
GOLGB1 golgin B1
GPN1 GPN-loop GTPase 1
GRAMD3 GRAM domain containing 3
GRB10 growth factor receptor-bound protein 10
GRIPAP1 GRIP1 associated protein 1
GRK6 G protein-coupled receptor kinase 6
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2I general transcription factor IIi
GTPBP1 GTP binding protein 1
HAUS6 HAUS augmin-like complex, subunit 6
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDGF hepatoma-derived growth factor
HDGFRP2 hepatoma-derived growth factor-related protein 2
HIPK1 homeodomain interacting protein kinase 1
HIRIP3 HIRA interacting protein 3
HIST1H1C histone cluster 1, H1c
HJURP Holliday junction recognition protein
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGN1 high mobility group nucleosome binding domain 1
HN1 hematological and neurological expressed 1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HSPA12B heat shock 70kD protein 12B
HSPB1 heat shock 27kDa protein 1
HTATSF1 HIV-1 Tat specific factor 1
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGHMBP2 immunoglobulin mu binding protein 2
IL6ST interleukin 6 signal transducer
ILF3 interleukin enhancer binding factor 3, 90kDa
INCENP inner centromere protein antigens 135/155kDa
INTS10 integrator complex subunit 10
IPO5 importin 5
IQSEC1 IQ motif and Sec7 domain 1
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF2BPL interferon regulatory factor 2 binding protein-like
IRS2 insulin receptor substrate 2
ISCU iron-sulfur cluster assembly enzyme
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN2 intersectin 2
IWS1 IWS1 homolog (S. cerevisiae)
JADE3 jade family PHD finger 3
JUND jun D proto-oncogene
KANSL1 KAT8 regulatory NSL complex subunit 1
KANSL2 KAT8 regulatory NSL complex subunit 2
KARS lysyl-tRNA synthetase
KAT7 K(lysine) acetyltransferase 7
KDM2A lysine (K)-specific demethylase 2A
KDM3B lysine (K)-specific demethylase 3B
KDM5A lysine (K)-specific demethylase 5A
KIAA0754 KIAA0754
KIAA1328 KIAA1328
KIAA1462 KIAA1462
KIAA1467 KIAA1467
KIAA1468 KIAA1468
KIAA1522 KIAA1522
KIAA1551 KIAA1551
KIF13A kinesin family member 13A
KIF1B kinesin family member 1B
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF7 kinesin family member 7
KLC1 kinesin light chain 1
KLF3 Kruppel-like factor 3 (basic)
KLHDC4 kelch domain containing 4
KRI1 KRI1 homolog (S. cerevisiae)
LACTB2 lactamase, beta 2
LARP1 La ribonucleoprotein domain family, member 1
LARP7 La ribonucleoprotein domain family, member 7
LCMT1 leucine carboxyl methyltransferase 1
LEMD3 LEM domain containing 3
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LIG1 ligase I, DNA, ATP-dependent
LIMCH1 LIM and calponin homology domains 1
LIMD1 LIM domains containing 1
LIN37 lin-37 DREAM MuvB core complex component
LIN9 lin-9 DREAM MuvB core complex component
LINS lines homolog (Drosophila)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMNA lamin A/C
LMNB1 lamin B1
LMO7 LIM domain 7
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC47 leucine rich repeat containing 47
LRRC59 leucine rich repeat containing 59
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSP1 lymphocyte-specific protein 1
LSR lipolysis stimulated lipoprotein receptor
LUZP1 leucine zipper protein 1
MACF1 microtubule-actin crosslinking factor 1
MAK16 MAK16 homolog (S. cerevisiae)
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAP1S microtubule-associated protein 1S
MAP2 microtubule-associated protein 2
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4 microtubule-associated protein 4
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP7D1 MAP7 domain containing 1
MAPK1 mitogen-activated protein kinase 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MAST2 microtubule associated serine/threonine kinase 2
MATR3 matrin 3
MB21D2 Mab-21 domain containing 2
MBD3 methyl-CpG binding domain protein 3
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM6 minichromosome maintenance complex component 6
MDC1 mediator of DNA-damage checkpoint 1
MDN1 MDN1, midasin homolog (yeast)
MEAF6 MYST/Esa1-associated factor 6
MET MET proto-oncogene, receptor tyrosine kinase
METTL16 methyltransferase like 16
MFAP1 microfibrillar-associated protein 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIA3 melanoma inhibitory activity family, member 3
MICALL1 MICAL-like 1
MIER1 mesoderm induction early response 1, transcriptional regulator
MKL1 megakaryoblastic leukemia (translocation) 1
MKL2 MKL/myocardin-like 2
MKRN2 makorin ring finger protein 2
MLF2 myeloid leukemia factor 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOV10 Mov10 RISC complex RNA helicase
MPDZ multiple PDZ domain protein
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MRGBP MRG/MORF4L binding protein
MRVI1 murine retrovirus integration site 1 homolog
MSH6 mutS homolog 6
MSL3 male-specific lethal 3 homolog (Drosophila)
MSRB3 methionine sulfoxide reductase B3
MTUS1 microtubule associated tumor suppressor 1
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12B myosin, light chain 12B, regulatory
MYO18A myosin XVIIIA
MYRF myelin regulatory factor
N4BP1 NEDD4 binding protein 1
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NACA nascent polypeptide-associated complex alpha subunit
NAP1L1 nucleosome assembly protein 1-like 1
NAP1L4 nucleosome assembly protein 1-like 4
NAV1 neuron navigator 1
NCAPD2 non-SMC condensin I complex, subunit D2
NCAPG non-SMC condensin I complex, subunit G
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCL nucleolin
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NECAP2 NECAP endocytosis associated 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEK1 NIMA-related kinase 1
NELFB negative elongation factor complex member B
NEMF nuclear export mediator factor
NES nestin
NEXN nexilin (F actin binding protein)
NF1 neurofibromin 1
NFIB nuclear factor I/B
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFIL3 nuclear factor, interleukin 3 regulated
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPBL Nipped-B homolog (Drosophila)
NISCH nischarin
NMD3 NMD3 ribosome export adaptor
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOL7 nucleolar protein 7, 27kDa
NOL8 nucleolar protein 8
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP56 NOP56 ribonucleoprotein
NOP58 NOP58 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPM3 nucleophosmin/nucleoplasmin 3
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRBP1 nuclear receptor binding protein 1
NT5C2 5'-nucleotidase, cytosolic II
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP160 nucleoporin 160kDa
NUP98 nucleoporin 98kDa
OGFR opioid growth factor receptor
OSBP oxysterol binding protein
OSBPL11 oxysterol binding protein-like 11
OSBPL3 oxysterol binding protein-like 3
OSBPL8 oxysterol binding protein-like 8
OTUD4 OTU deubiquitinase 4
OTUD5 OTU deubiquitinase 5
OTUD7B OTU deubiquitinase 7B
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALLD palladin, cytoskeletal associated protein
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARD3 par-3 family cell polarity regulator
PARN poly(A)-specific ribonuclease
PAXBP1 PAX3 and PAX7 binding protein 1
PBRM1 polybromo 1
PCBP1 poly(rC) binding protein 1
PCM1 pericentriolar material 1
PCNT pericentrin
PDAP1 PDGFA associated protein 1
PDCD5 programmed cell death 5
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDIA6 protein disulfide isomerase family A, member 6
PDLIM4 PDZ and LIM domain 4
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PDS5B PDS5 cohesin associated factor B
PEA15 phosphoprotein enriched in astrocytes 15
PEAK1 pseudopodium-enriched atypical kinase 1
PFKL phosphofructokinase, liver
PGRMC1 progesterone receptor membrane component 1
PGRMC2 progesterone receptor membrane component 2
PHACTR4 phosphatase and actin regulator 4
PHC3 polyhomeotic homolog 3 (Drosophila)
PHF10 PHD finger protein 10
PHF14 PHD finger protein 14
PHF3 PHD finger protein 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKN1 protein kinase N1
PKN2 protein kinase N2
PLCD1 phospholipase C, delta 1
PLCL1 phospholipase C-like 1
PLEC plectin
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
PLVAP plasmalemma vesicle associated protein
PLXDC2 plexin domain containing 2
PNN pinin, desmosome associated protein
POGZ pogo transposable element with ZNF domain
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU2F1 POU class 2 homeobox 1
PPAN peter pan homolog (Drosophila)
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4
PPL periplakin
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCDBP protein kinase C, delta binding protein
PRKCI protein kinase C, iota
PRKD1 protein kinase D1
PRKG1 protein kinase, cGMP-dependent, type I
PRPF3 pre-mRNA processing factor 3
PRPF38A pre-mRNA processing factor 38A
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRPF6 pre-mRNA processing factor 6
PRR12 proline rich 12
PRRC2A proline-rich coiled-coil 2A
PRRC2B proline-rich coiled-coil 2B
PRRC2C proline-rich coiled-coil 2C
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTK2 protein tyrosine kinase 2
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTRF polymerase I and transcript release factor
PUM1 pumilio RNA-binding family member 1
PWP1 PWP1 homolog (S. cerevisiae)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PXN paxillin
QSER1 glutamine and serine rich 1
R3HDM2 R3H domain containing 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABL6 RAB, member RAS oncogene family-like 6
RACGAP1 Rac GTPase activating protein 1
RANBP1 RAN binding protein 1
RANBP10 RAN binding protein 10
RANBP2 RAN binding protein 2
RANBP3 RAN binding protein 3
RANGAP1 Ran GTPase activating protein 1
RB1CC1 RB1-inducible coiled-coil 1
RBBP6 retinoblastoma binding protein 6
RBM15 RNA binding motif protein 15
RBM28 RNA binding motif protein 28
RBM33 RNA binding motif protein 33
RBM7 RNA binding motif protein 7
RBMS2 RNA binding motif, single stranded interacting protein 2
RBMX RNA binding motif protein, X-linked
RBMX2 RNA binding motif protein, X-linked 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RFC1 replication factor C (activator 1) 1, 145kDa
RIC8A RIC8 guanine nucleotide exchange factor A
RIF1 replication timing regulatory factor 1
RIN1 Ras and Rab interactor 1
RIOK1 RIO kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RNF219 ring finger protein 219
RNF220 ring finger protein 220
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RPLP0 ribosomal protein, large, P0
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RPS3 ribosomal protein S3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRAGC Ras-related GTP binding C
RRM2 ribonucleotide reductase M2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RSL1D1 ribosomal L1 domain containing 1
RTN4 reticulon 4
SAMD4A sterile alpha motif domain containing 4A
SAMHD1 SAM domain and HD domain 1
SAP30 Sin3A-associated protein, 30kDa
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAF1 SR-related CTD-associated factor 1
SCAF11 SR-related CTD-associated factor 11
SCARF2 scavenger receptor class F, member 2
SCEL sciellin
SCRIB scribbled planar cell polarity protein
SDPR serum deprivation response
SEC16A SEC16 homolog A (S. cerevisiae)
SEC31A SEC31 homolog A (S. cerevisiae)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SEPT2 septin 2
SEPT4 septin 4
SEPT9 septin 9
SERBP1 SERPINE1 mRNA binding protein 1
SETD1A SET domain containing 1A
SETD2 SET domain containing 2
SETD6 SET domain containing 6
SF1 splicing factor 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFR1 SWI5-dependent recombination repair 1
SFSWAP splicing factor, suppressor of white-apricot family
SH3BP5L SH3-binding domain protein 5-like
SH3KBP1 SH3-domain kinase binding protein 1
SH3RF1 SH3 domain containing ring finger 1
SHROOM2 shroom family member 2
SHROOM3 shroom family member 3
SIK2 salt-inducible kinase 2
SIN3A SIN3 transcription regulator family member A
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC45A4 solute carrier family 45, member 4
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLK STE20-like kinase
SLTM SAFB-like, transcription modulator
SLX4 SLX4 structure-specific endonuclease subunit
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SMN1 survival of motor neuron 1, telomeric
SMTNL2 smoothelin-like 2
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNX17 sorting nexin 17
SNX3 sorting nexin 3
SON SON DNA binding protein
SORBS1 sorbin and SH3 domain containing 1
SPAG9 sperm associated antigen 9
SPATS2 spermatogenesis associated, serine-rich 2
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPTBN1 spectrin, beta, non-erythrocytic 1
SRCAP Snf2-related CREBBP activator protein
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRP72 signal recognition particle 72kDa
SRPK1 SRSF protein kinase 1
SRPK2 SRSF protein kinase 2
SRPR signal recognition particle receptor (docking protein)
SRRM1 serine/arginine repetitive matrix 1
SRRM2 serine/arginine repetitive matrix 2
SRSF2 serine/arginine-rich splicing factor 2
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
SSFA2 sperm specific antigen 2
SSR1 signal sequence receptor, alpha
SSRP1 structure specific recognition protein 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD3NL STARD3 N-terminal like
STK10 serine/threonine kinase 10
STK4 serine/threonine kinase 4
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STXBP5 syntaxin binding protein 5 (tomosyn)
SUGP1 SURP and G patch domain containing 1
SUN2 Sad1 and UNC84 domain containing 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SVIL supervillin
SYAP1 synapse associated protein 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNPO synaptopodin
TACC2 transforming, acidic coiled-coil containing protein 2
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D10B TBC1 domain family, member 10B
TBC1D12 TBC1 domain family, member 12
TBC1D25 TBC1 domain family, member 25
TBC1D2B TBC1 domain family, member 2B
TBC1D4 TBC1 domain family, member 4
TCF20 transcription factor 20 (AR1)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEX2 testis expressed 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFEB transcription factor EB
TFIP11 tuftelin interacting protein 11
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGS1 trimethylguanosine synthase 1
THOC2 THO complex 2
THOC5 THO complex 5
THRAP3 thyroid hormone receptor associated protein 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLN1 talin 1
TMEM230 transmembrane protein 230
TMF1 TATA element modulatory factor 1
TMPO thymopoietin
TMX1 thioredoxin-related transmembrane protein 1
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa
TNS1 tensin 1
TNS2 tensin 2
TNS3 tensin 3
TOE1 target of EGR1, member 1 (nuclear)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53BP1 tumor protein p53 binding protein 1
TP53BP2 tumor protein p53 binding protein 2
TPD52L2 tumor protein D52-like 2
TPM1 tropomyosin 1 (alpha)
TPR translocated promoter region, nuclear basket protein
TRA2A transformer 2 alpha homolog (Drosophila)
TRAM1 translocation associated membrane protein 1
TRAPPC12 trafficking protein particle complex 12
TRIM28 tripartite motif containing 28
TRIM56 tripartite motif containing 56
TRIO trio Rho guanine nucleotide exchange factor
TRIP12 thyroid hormone receptor interactor 12
TSC1 tuberous sclerosis 1
TSC22D4 TSC22 domain family, member 4
TTC28 tetratricopeptide repeat domain 28
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TWF1 twinfilin actin binding protein 1
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBA1 ubiquitin-like modifier activating enzyme 1
UBAP2L ubiquitin associated protein 2-like
UBE2O ubiquitin-conjugating enzyme E2O
UBXN7 UBX domain protein 7
UHRF1BP1 UHRF1 binding protein 1
UIMC1 ubiquitin interaction motif containing 1
UNC119 unc-119 homolog (C. elegans)
USO1 USO1 vesicle transport factor
USP10 ubiquitin specific peptidase 10
USP15 ubiquitin specific peptidase 15
USP20 ubiquitin specific peptidase 20
USP34 ubiquitin specific peptidase 34
USP36 ubiquitin specific peptidase 36
USP9X ubiquitin specific peptidase 9, X-linked
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VCL vinculin
VILL villin-like
VIM vimentin
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WAPAL wings apart-like homolog (Drosophila)
WDR3 WD repeat domain 3
WDR44 WD repeat domain 44
WDR70 WD repeat domain 70
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNK1 WNK lysine deficient protein kinase 1
WRNIP1 Werner helicase interacting protein 1
WWC2 WW and C2 domain containing 2
WWTR1 WW domain containing transcription regulator 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX3 Y box binding protein 3
YEATS2 YEATS domain containing 2
ZBTB21 zinc finger and BTB domain containing 21
ZC3H13 zinc finger CCCH-type containing 13
ZC3H18 zinc finger CCCH-type containing 18
ZC3H4 zinc finger CCCH-type containing 4
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZC3HC1 zinc finger, C3HC-type containing 1
ZDHHC8 zinc finger, DHHC-type containing 8
ZFAND5 zinc finger, AN1-type domain 5
ZFC3H1 zinc finger, C3H1-type containing
ZFX zinc finger protein, X-linked
ZMYM2 zinc finger, MYM-type 2
ZMYM3 zinc finger, MYM-type 3
ZMYND8 zinc finger, MYND-type containing 8
ZNF318 zinc finger protein 318
ZNF687 zinc finger protein 687
ZNF830 zinc finger protein 830
ZNHIT3 zinc finger, HIT-type containing 3
ZRANB2 zinc finger, RAN-binding domain containing 2
ZWINT ZW10 interacting kinetochore protein
ZYX zyxin

decreased phosphorylation

Symbol Name
AFAP1L2 actin filament associated protein 1-like 2
AHNAK2 AHNAK nucleoprotein 2
AP1M1 adaptor-related protein complex 1, mu 1 subunit
ARF4 ADP-ribosylation factor 4
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BORA bora, aurora kinase A activator
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C1ORF131 chromosome 1 open reading frame 131
C6ORF203 chromosome 6 open reading frame 203
C8ORF33 chromosome 8 open reading frame 33
CCDC102A coiled-coil domain containing 102A
CCDC85C coiled-coil domain containing 85C
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNTNAP3 contactin associated protein-like 3
DENND1B DENN/MADD domain containing 1B
DTD1 D-tyrosyl-tRNA deacylase 1
DTNB dystrobrevin, beta
DTNBP1 dystrobrevin binding protein 1
DZIP1L DAZ interacting zinc finger protein 1-like
EPYC epiphycan
ETL4 epilepsy, occipitotemporal lobe, and migraine with aura
FAM13C family with sequence similarity 13, member C
FAM171A1 family with sequence similarity 171, member A1
FILIP1L filamin A interacting protein 1-like
GPR39 G protein-coupled receptor 39
HELLS helicase, lymphoid-specific
HIST1H2BJ histone cluster 1, H2bj
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
KDM4B lysine (K)-specific demethylase 4B
KRT19 keratin 19, type I
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LDHD lactate dehydrogenase D
LIME1 Lck interacting transmembrane adaptor 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAST4 microtubule associated serine/threonine kinase family member 4
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MUM1L1 melanoma associated antigen (mutated) 1-like 1
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NEUROD1 neuronal differentiation 1
NKAPL NFKB activating protein-like
NUCB1 nucleobindin 1
PARD6B par-6 family cell polarity regulator beta
PDZD2 PDZ domain containing 2
PEG3 paternally expressed 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PSAT1 phosphoserine aminotransferase 1
PUS7 pseudouridylate synthase 7 (putative)
PVR poliovirus receptor
RAB14 RAB14, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RARG retinoic acid receptor, gamma
REEP1 receptor accessory protein 1
RFTN2 raftlin family member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC44A2 solute carrier family 44 (choline transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SNX24 sorting nexin 24
SNX30 sorting nexin family member 30
TECPR2 tectonin beta-propeller repeat containing 2
TFE3 transcription factor binding to IGHM enhancer 3
UNK unkempt family zinc finger
ZNF131 zinc finger protein 131
ZNF395 zinc finger protein 395
ZNF516 zinc finger protein 516