| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SFPQ | splicing factor proline/glutamine-rich | 0.0463634 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0444737 |
| RPS3 | ribosomal protein S3 | 0.0435351 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0433085 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0398702 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.039575 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387214 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.038492 |
| PCBP2 | poly(rC) binding protein 2 | 0.0365818 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0347123 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0337096 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0334544 |
| CMIP | c-Maf inducing protein | 0.0331381 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.033078 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0322827 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.03212 |
| MED13L | mediator complex subunit 13-like | 0.0320329 |
| EDN1 | endothelin 1 | 0.0318087 |
| YBX3 | Y box binding protein 3 | 0.0298265 |
| CCNL1 | cyclin L1 | 0.0297115 |
| INTS6 | integrator complex subunit 6 | 0.0296868 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0293572 |
| CALR | calreticulin | 0.0288549 |
| EXOC6B | exocyst complex component 6B | 0.0282613 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0276465 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0274735 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0271486 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0257077 |
| CCDC88A | coiled-coil domain containing 88A | 0.0255301 |
| CALD1 | caldesmon 1 | 0.0251214 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0244879 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0238378 |
| SPAG9 | sperm associated antigen 9 | 0.0234751 |
| NFIB | nuclear factor I/B | 0.0234297 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0232761 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0231865 |
| NEGR1 | neuronal growth regulator 1 | 0.0229254 |
| RPL21 | ribosomal protein L21 | 0.0228909 |
| ERBIN | erbb2 interacting protein | 0.02274 |
| PLK2 | polo-like kinase 2 | 0.0224087 |
| DENND5A | DENN/MADD domain containing 5A | 0.022303 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0218602 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0210067 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0209824 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0208921 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0207125 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0202034 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0200271 |
| CLPTM1L | CLPTM1-like | 0.0198833 |
| NEK7 | NIMA-related kinase 7 | 0.0198663 |
| FLNA | filamin A, alpha | 0.0198331 |
| OXR1 | oxidation resistance 1 | 0.0197366 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0196218 |
| NRXN3 | neurexin 3 | 0.0194706 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0187905 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0187351 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0184959 |
| RPS12 | ribosomal protein S12 | 0.0184659 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0182476 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0182453 |
| PCM1 | pericentriolar material 1 | 0.0179512 |
| RPL9 | ribosomal protein L9 | 0.0173333 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0172713 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0170741 |
| DIAPH1 | diaphanous-related formin 1 | 0.0169986 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0168887 |
| SYT1 | synaptotagmin I | 0.0165796 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0165394 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0165169 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0164339 |
| DST | dystonin | 0.0163638 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0163259 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0163212 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0160013 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0156848 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0156181 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0156089 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0155796 |
| RPL13A | ribosomal protein L13a | 0.0155531 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0154379 |
| CEP70 | centrosomal protein 70kDa | 0.0153801 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0153714 |
| SON | SON DNA binding protein | 0.0153704 |
| RPL26 | ribosomal protein L26 | 0.0152618 |
| CEP192 | centrosomal protein 192kDa | 0.0152219 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0151806 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0151708 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.015091 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0149112 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0148892 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.014851 |
| TOP1 | topoisomerase (DNA) I | 0.0147906 |
| FRYL | FRY-like | 0.0147431 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0146685 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0145723 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0144571 |
| PTMS | parathymosin | 0.0144548 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0144049 |
| POU2F1 | POU class 2 homeobox 1 | 0.0143837 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.014041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.378537 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0999594 |
| MMP12 | matrix metallopeptidase 12 | -0.0938169 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0843073 |
| AREG | amphiregulin | -0.0826298 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0787129 |
| ACTG1 | actin gamma 1 | -0.0779393 |
| ASPH | aspartate beta-hydroxylase | -0.0713219 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.070063 |
| NHSL1 | NHS-like 1 | -0.066089 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0645486 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.06288 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.061341 |
| RPL35A | ribosomal protein L35a | -0.0604182 |
| MKI67 | marker of proliferation Ki-67 | -0.0603774 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0600653 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0577046 |
| BCHE | butyrylcholinesterase | -0.0572802 |
| AHNAK | AHNAK nucleoprotein | -0.0570833 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0558007 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0555241 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0541094 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0518477 |
| H1-0 | H1.0 linker histone | -0.051776 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0506825 |
| VIM | vimentin | -0.0495614 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0493107 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0452041 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0444844 |
| VMP1 | vacuole membrane protein 1 | -0.0413518 |
| TPM4 | tropomyosin 4 | -0.0396207 |
| LDHB | lactate dehydrogenase B | -0.039579 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0394598 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0389584 |
| TMEM123 | transmembrane protein 123 | -0.0389489 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.038648 |
| FTL | ferritin, light polypeptide | -0.0379631 |
| ANXA1 | annexin A1 | -0.0377178 |
| TUBB | tubulin, beta class I | -0.0374872 |
| PCDH7 | protocadherin 7 | -0.0368024 |
| XPO1 | exportin 1 | -0.0367439 |
| S100A10 | S100 calcium binding protein A10 | -0.0361201 |
| MTAP | methylthioadenosine phosphorylase | -0.03538 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0352969 |
| ENO1 | enolase 1, (alpha) | -0.0351544 |
| IPO7 | importin 7 | -0.0349184 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0343719 |
| CCND1 | cyclin D1 | -0.0343273 |
| PCDH9 | protocadherin 9 | -0.0342009 |
| ZNF804A | zinc finger protein 804A | -0.0340509 |
| RPLP1 | ribosomal protein, large, P1 | -0.0339706 |
| CANX | calnexin | -0.0331957 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.033034 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322397 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0322174 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0304096 |
| RPL38 | ribosomal protein L38 | -0.0300103 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0295291 |
| RPL19 | ribosomal protein L19 | -0.0295242 |
| SQSTM1 | sequestosome 1 | -0.0288911 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0285757 |
| EDARADD | EDAR-associated death domain | -0.0285078 |
| H3-3B | H3.3 histone B | -0.0280923 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0279153 |
| S100A6 | S100 calcium binding protein A6 | -0.0279084 |
| RPL8 | ribosomal protein L8 | -0.027842 |
| TUBA1B | tubulin, alpha 1b | -0.0276801 |
| TPI1 | triosephosphate isomerase 1 | -0.0272121 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.026534 |
| RPS29 | ribosomal protein S29 | -0.0263534 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.026329 |
| NAV3 | neuron navigator 3 | -0.0262729 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0262616 |
| RPS6 | ribosomal protein S6 | -0.0259841 |
| BRI3BP | BRI3 binding protein | -0.0257054 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0254848 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0252654 |
| WDR45B | WD repeat domain 45B | -0.0252251 |
| MAP1B | microtubule-associated protein 1B | -0.0249982 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0247722 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0247598 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0246849 |
| PTMA | prothymosin, alpha | -0.0244085 |
| RPS21 | ribosomal protein S21 | -0.024297 |
| YAP1 | Yes-associated protein 1 | -0.0242275 |
| PRR11 | proline rich 11 | -0.0240051 |
| YEATS2 | YEATS domain containing 2 | -0.0237969 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0237597 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235174 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0233018 |
| NLGN1 | neuroligin 1 | -0.02304 |
| RPS16 | ribosomal protein S16 | -0.0230307 |
| EHBP1 | EH domain binding protein 1 | -0.0230249 |
| RPS13 | ribosomal protein S13 | -0.0227762 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0226807 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0226102 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.022065 |
| CDK17 | cyclin-dependent kinase 17 | -0.0217339 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0217302 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0216253 |
