| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PHF3 | PHD finger protein 3 | 0.0958992 |
| INTS6 | integrator complex subunit 6 | 0.0895744 |
| LMO7 | LIM domain 7 | 0.0816575 |
| PLSCR2 | phospholipid scramblase 2 | 0.0520565 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0511492 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.050922 |
| ANXA2 | annexin A2 | 0.0436609 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0436042 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.039983 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0379657 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0357395 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0339571 |
| MCL1 | myeloid cell leukemia 1 | 0.033364 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0319724 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0314892 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306235 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.03052 |
| POU2F2 | POU class 2 homeobox 2 | 0.029592 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0294394 |
| MLPH | melanophilin | 0.0292769 |
| STK24 | serine/threonine kinase 24 | 0.0285417 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0279699 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0271218 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0262528 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0259924 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252197 |
| EZR | ezrin | 0.0246834 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0243719 |
| VEGFA | vascular endothelial growth factor A | 0.0242109 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0236332 |
| SETX | senataxin | 0.023397 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0229241 |
| SMAD3 | SMAD family member 3 | 0.0227264 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0222318 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0221009 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.02197 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.021606 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.021382 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0213656 |
| CDHR2 | cadherin-related family member 2 | 0.0213526 |
| EGFR | epidermal growth factor receptor | 0.0210626 |
| TMC5 | transmembrane channel-like 5 | 0.0195402 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0193412 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0192428 |
| RAD51B | RAD51 paralog B | 0.0192298 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0190913 |
| MYO10 | myosin X | 0.0188242 |
| NABP1 | nucleic acid binding protein 1 | 0.0186202 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0184862 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0182503 |
| PSPC1 | paraspeckle component 1 | 0.0180816 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0179343 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0178028 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0174366 |
| VMP1 | vacuole membrane protein 1 | 0.017084 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0166337 |
| SEPTIN9 | septin 9 | 0.0162209 |
| COG3 | component of oligomeric golgi complex 3 | 0.0161461 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0161333 |
| NUP98 | nucleoporin 98kDa | 0.0160141 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0153513 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0152168 |
| UBAP2 | ubiquitin associated protein 2 | 0.0151784 |
| TNS4 | tensin 4 | 0.0151407 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.015111 |
| ACTN1 | actinin, alpha 1 | 0.0150631 |
| KIF16B | kinesin family member 16B | 0.0149966 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0147038 |
| TUFT1 | tuftelin 1 | 0.0146573 |
| TMEM65 | transmembrane protein 65 | 0.0144391 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0143759 |
| TSPYL2 | TSPY-like 2 | 0.014167 |
| MYO5B | myosin VB | 0.0141443 |
| MYO1E | myosin IE | 0.0140859 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0139698 |
| EXOC4 | exocyst complex component 4 | 0.013844 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0138332 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0137945 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0134761 |
| BRD9 | bromodomain containing 9 | 0.0132593 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 | 0.0132031 |
| SZT2 | seizure threshold 2 homolog (mouse) | 0.0131718 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0131278 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0130858 |
| GOLGA3 | golgin A3 | 0.0128222 |
| GALK2 | galactokinase 2 | 0.0127583 |
| SERINC5 | serine incorporator 5 | 0.0127437 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 | 0.0126436 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0125315 |
| EPHA2 | EPH receptor A2 | 0.0124132 |
| JAK1 | Janus kinase 1 | 0.01234 |
| SDCBP | syndecan binding protein (syntenin) | 0.0123286 |
| KIAA1671 | KIAA1671 | 0.0123087 |
| GON4L | gon-4-like (C. elegans) | 0.012242 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0121509 |
| KAZN | kazrin, periplakin interacting protein | 0.0121188 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0120992 |
| OTUD5 | OTU deubiquitinase 5 | 0.0120491 |
| WWOX | WW domain containing oxidoreductase | 0.0119776 |
| PDZD8 | PDZ domain containing 8 | 0.011975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.22598 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.186603 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.165526 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156134 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128168 |
| HLA-B | major histocompatibility complex, class I, B | -0.125937 |
| PTMA | prothymosin, alpha | -0.1155 |
| LCN2 | lipocalin 2 | -0.0961257 |
| H1-0 | H1.0 linker histone | -0.0864577 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0732492 |
| TMSB10 | thymosin beta 10 | -0.0684024 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0621231 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0616557 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0609515 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0600394 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0595334 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0589812 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0566166 |
| MT2A | metallothionein 2A | -0.0555764 |
| UBC | ubiquitin C | -0.0552737 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.054003 |
| XAF1 | XIAP associated factor 1 | -0.0518814 |
| RNF149 | ring finger protein 149 | -0.0507447 |
| TXNIP | thioredoxin interacting protein | -0.0504856 |
| RPL35A | ribosomal protein L35a | -0.0498807 |
| PERP | PERP, TP53 apoptosis effector | -0.0498431 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0494603 |
| S100A6 | S100 calcium binding protein A6 | -0.0475368 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0469584 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0457429 |
| RUNX1 | runt-related transcription factor 1 | -0.0457348 |
| HLA-C | major histocompatibility complex, class I, C | -0.0453196 |
| LYZ | lysozyme | -0.0453121 |
| RPS6 | ribosomal protein S6 | -0.0448719 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.044682 |
| KLF6 | Kruppel-like factor 6 | -0.0445607 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0444458 |
| FTL | ferritin, light polypeptide | -0.0442548 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0439478 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0434816 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0430957 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0427213 |
| MKI67 | marker of proliferation Ki-67 | -0.0424744 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0421898 |
| RPL23 | ribosomal protein L23 | -0.0416693 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0410704 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0409564 |
| RPS24 | ribosomal protein S24 | -0.0409355 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0404168 |
| NDRG1 | N-myc downstream regulated 1 | -0.0397865 |
| RPL12 | ribosomal protein L12 | -0.0397122 |
| RPS8 | ribosomal protein S8 | -0.0396839 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0396279 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0396 |
| RPS19 | ribosomal protein S19 | -0.0390091 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0384154 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0384139 |
| KRT19 | keratin 19, type I | -0.0380174 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0378891 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0378255 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0375675 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0374525 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0372699 |
| ABLIM1 | actin binding LIM protein 1 | -0.037036 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.036742 |
| CANX | calnexin | -0.0366511 |
| H3-3B | H3.3 histone B | -0.0364578 |
| EPCAM | epithelial cell adhesion molecule | -0.0363852 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0362157 |
| PTGR1 | prostaglandin reductase 1 | -0.0361196 |
| ENO1 | enolase 1, (alpha) | -0.0359815 |
| APOL1 | apolipoprotein L, 1 | -0.0357073 |
| RRBP1 | ribosome binding protein 1 | -0.0352677 |
| CALR | calreticulin | -0.0352472 |
| RPL34 | ribosomal protein L34 | -0.0351909 |
| ASPH | aspartate beta-hydroxylase | -0.0349129 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0348723 |
| GNAS | GNAS complex locus | -0.0348322 |
| RPL19 | ribosomal protein L19 | -0.0344569 |
| RPLP1 | ribosomal protein, large, P1 | -0.0342755 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0342631 |
| DIAPH3 | diaphanous-related formin 3 | -0.0340824 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0336096 |
| AHNAK | AHNAK nucleoprotein | -0.0333779 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0333456 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.032708 |
| TPI1 | triosephosphate isomerase 1 | -0.0323742 |
| PRKCA | protein kinase C, alpha | -0.031941 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0317009 |
| LDHA | lactate dehydrogenase A | -0.0316088 |
| DSTN | destrin (actin depolymerizing factor) | -0.0312764 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0312303 |
| WDR45B | WD repeat domain 45B | -0.0309995 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0309681 |
| NCKAP5 | NCK-associated protein 5 | -0.0307481 |
| S100A10 | S100 calcium binding protein A10 | -0.0300485 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0300065 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0299886 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0296067 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0295431 |
