| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rapamycin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.161805 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.133338 |
| NDRG1 | N-myc downstream regulated 1 | 0.131951 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.129524 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.113296 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0973126 |
| CADM1 | cell adhesion molecule 1 | 0.0949205 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0846194 |
| NAV2 | neuron navigator 2 | 0.0786287 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0742258 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0717268 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0630318 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.058133 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.054497 |
| CDH13 | cadherin 13 | 0.0544163 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0523695 |
| EGFR | epidermal growth factor receptor | 0.050905 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0501731 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0478174 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0396591 |
| PLEC | plectin | 0.0370648 |
| MYO10 | myosin X | 0.0370574 |
| FLNA | filamin A, alpha | 0.0356909 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0346359 |
| RUNX1 | runt-related transcription factor 1 | 0.0345723 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0340454 |
| MSN | moesin | 0.0306074 |
| FNIP1 | folliculin interacting protein 1 | 0.0300258 |
| HDAC9 | histone deacetylase 9 | 0.0297654 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0296041 |
| FMNL2 | formin-like 2 | 0.029361 |
| CMIP | c-Maf inducing protein | 0.02891 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0271458 |
| GOLGB1 | golgin B1 | 0.0268116 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0261776 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0259242 |
| GOLGA4 | golgin A4 | 0.0259221 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0254702 |
| SQSTM1 | sequestosome 1 | 0.0254629 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0252496 |
| PCBP2 | poly(rC) binding protein 2 | 0.0251966 |
| NOTCH2 | notch 2 | 0.0249832 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246056 |
| PGM3 | phosphoglucomutase 3 | 0.0244138 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0243615 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0243447 |
| TNS1 | tensin 1 | 0.0242841 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0233784 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0227832 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0226285 |
| NAV1 | neuron navigator 1 | 0.022123 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0220994 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0219943 |
| FBXO32 | F-box protein 32 | 0.021852 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0217059 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0215358 |
| ZNF292 | zinc finger protein 292 | 0.0211959 |
| PTK2 | protein tyrosine kinase 2 | 0.0211876 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0210188 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0208154 |
| STC2 | stanniocalcin 2 | 0.0203738 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0202604 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0202152 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0201119 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0199504 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0199389 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0199145 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0198262 |
| MTSS1 | metastasis suppressor 1 | 0.0195329 |
| ARRDC3 | arrestin domain containing 3 | 0.0195086 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0194717 |
| RND3 | Rho family GTPase 3 | 0.0193098 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0192991 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0192851 |
| HSPA8 | heat shock 70kDa protein 8 | 0.019265 |
| SMAD3 | SMAD family member 3 | 0.0192541 |
| COL7A1 | collagen, type VII, alpha 1 | 0.019201 |
| RASA2 | RAS p21 protein activator 2 | 0.019008 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0189569 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0188205 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0187755 |
| COL5A1 | collagen, type V, alpha 1 | 0.0184036 |
| DSPP | dentin sialophosphoprotein | 0.0183522 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0179677 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0177631 |
| MED15 | mediator complex subunit 15 | 0.0175458 |
| IL6 | interleukin 6 | 0.0174891 |
| ATXN1 | ataxin 1 | 0.0172151 |
| EFNA5 | ephrin-A5 | 0.0170708 |
| RPS12 | ribosomal protein S12 | 0.0170031 |
| ADM | adrenomedullin | 0.0169902 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0169819 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0168695 |
| CCNY | cyclin Y | 0.0168424 |
| MSI2 | musashi RNA-binding protein 2 | 0.0168005 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0166307 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0164991 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0164366 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0164249 |
| ANXA5 | annexin A5 | 0.0164024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.321812 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202435 |
| COL1A2 | collagen, type I, alpha 2 | -0.143967 |
| VIM | vimentin | -0.136015 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113615 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.112376 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0952521 |
| TMSB10 | thymosin beta 10 | -0.0897385 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0889635 |
| CD44 | CD44 molecule (Indian blood group) | -0.0789808 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0631703 |
| FBN1 | fibrillin 1 | -0.058134 |
| LOX | lysyl oxidase | -0.0550457 |
| HMGA2 | high mobility group AT-hook 2 | -0.0515722 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0511252 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0503849 |
| MT2A | metallothionein 2A | -0.0488487 |
| RRBP1 | ribosome binding protein 1 | -0.0485994 |
| PALLD | palladin, cytoskeletal associated protein | -0.0465816 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0465308 |
| MAP1B | microtubule-associated protein 1B | -0.0458674 |
| GLIS3 | GLIS family zinc finger 3 | -0.044191 |
| ASPH | aspartate beta-hydroxylase | -0.0433213 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.041124 |
| OSMR | oncostatin M receptor | -0.0393669 |
| CAVIN1 | caveolae associated protein 1 | -0.0392025 |
| LDHA | lactate dehydrogenase A | -0.0387772 |
| AHNAK | AHNAK nucleoprotein | -0.0379502 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0374102 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0344992 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0342971 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0341806 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0336668 |
| CANX | calnexin | -0.0332807 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0321513 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0319169 |
| VCL | vinculin | -0.031882 |
| HLA-B | major histocompatibility complex, class I, B | -0.0307187 |
| CALD1 | caldesmon 1 | -0.0307119 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0306337 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0294915 |
| NREP | neuronal regeneration related protein | -0.0293689 |
| LOC112694756 | uncharaterized LOC112694756 | -0.029217 |
| STC1 | stanniocalcin 1 | -0.0291399 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.028967 |
| EBF1 | early B-cell factor 1 | -0.0285737 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0284904 |
| CALU | calumenin | -0.0284077 |
| FN1 | fibronectin 1 | -0.0275172 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0269876 |
| S100A6 | S100 calcium binding protein A6 | -0.0263475 |
| VCAN | versican | -0.0259404 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025892 |
| MT1X | metallothionein 1X | -0.0256094 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0251602 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0243301 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0242349 |
| FTL | ferritin, light polypeptide | -0.0242045 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0240208 |
| KLF6 | Kruppel-like factor 6 | -0.0240202 |
| ACTG1 | actin gamma 1 | -0.0238969 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0237828 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0236875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0229583 |
| ANXA2 | annexin A2 | -0.0227514 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0223817 |
| RIGI | RNA sensor RIG-I | -0.0216587 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0215265 |
| SQLE | squalene epoxidase | -0.0212729 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0212573 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0211693 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.02034 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0197555 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.019255 |
| RPL35A | ribosomal protein L35a | -0.0192451 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0189882 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0186599 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0181646 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0181338 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0171215 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.017104 |
| FSTL1 | follistatin-like 1 | -0.0170832 |
| TPI1 | triosephosphate isomerase 1 | -0.0170779 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0168483 |
| NF1 | neurofibromin 1 | -0.0167361 |
| HDLBP | high density lipoprotein binding protein | -0.0166796 |
| RSU1 | Ras suppressor protein 1 | -0.0166488 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0164283 |
| POSTN | periostin, osteoblast specific factor | -0.0163338 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.016224 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0161669 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0160721 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0159643 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0159451 |
| PRSS23 | protease, serine, 23 | -0.0158206 |
| PTMA | prothymosin, alpha | -0.0153577 |
| S100A10 | S100 calcium binding protein A10 | -0.0151078 |
| TPM4 | tropomyosin 4 | -0.0150414 |
| LIMA1 | LIM domain and actin binding 1 | -0.0149561 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0149274 |
