| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.276494 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.174867 |
| FN1 | fibronectin 1 | 0.155779 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.123604 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0946166 |
| ENO1 | enolase 1, (alpha) | 0.0918387 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0844602 |
| ATXN1 | ataxin 1 | 0.0822053 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0787005 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.075517 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0733185 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0732153 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0729261 |
| ASPH | aspartate beta-hydroxylase | 0.0667397 |
| PEG3 | paternally expressed 3 | 0.0662916 |
| FMNL2 | formin-like 2 | 0.0659507 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0658084 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.065738 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0643775 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0636413 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0626144 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0611796 |
| TNS1 | tensin 1 | 0.0611086 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0594168 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0576081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0571504 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0570936 |
| RUNX1 | runt-related transcription factor 1 | 0.0550435 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0548977 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0547798 |
| EHBP1 | EH domain binding protein 1 | 0.054771 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0534331 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0529697 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0523826 |
| FRMD5 | FERM domain containing 5 | 0.0520534 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0506173 |
| CTSB | cathepsin B | 0.0495445 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0485172 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0479148 |
| PLIN2 | perilipin 2 | 0.0467653 |
| TPM4 | tropomyosin 4 | 0.0465973 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0464178 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.045362 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0427132 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0424404 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.042296 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0422223 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0419117 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0411693 |
| TXNRD1 | thioredoxin reductase 1 | 0.0410027 |
| TMEM123 | transmembrane protein 123 | 0.0404195 |
| MSI2 | musashi RNA-binding protein 2 | 0.0404077 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0401343 |
| APOA2 | apolipoprotein A-II | 0.0399143 |
| CP | ceruloplasmin (ferroxidase) | 0.0398168 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0381524 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0381437 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0377479 |
| GK | glycerol kinase | 0.0377007 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0376701 |
| DSPP | dentin sialophosphoprotein | 0.0373773 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0368454 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0366696 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0359881 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0359503 |
| RAI14 | retinoic acid induced 14 | 0.035828 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0353371 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0352208 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0343617 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0335343 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0331272 |
| ARFGEF3 | ARFGEF family member 3 | 0.0329434 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0327597 |
| ATP10A | ATPase, class V, type 10A | 0.0326899 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0321969 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0318822 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0317763 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0314789 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0314656 |
| RPL35A | ribosomal protein L35a | 0.0312308 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0310585 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0307155 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0303802 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0299275 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0298907 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0294773 |
| STK17A | serine/threonine kinase 17a | 0.0293854 |
| PLEC | plectin | 0.0291841 |
| TNS3 | tensin 3 | 0.0291502 |
| PTK2 | protein tyrosine kinase 2 | 0.0288983 |
| FAM13A | family with sequence similarity 13, member A | 0.0286894 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0285664 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0284845 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0279983 |
| FTL | ferritin, light polypeptide | 0.0279583 |
| GLG1 | golgi glycoprotein 1 | 0.0279069 |
| PGK1 | phosphoglycerate kinase 1 | 0.0278707 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0277804 |
| NDRG1 | N-myc downstream regulated 1 | 0.0277535 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.027753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.179562 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.130528 |
| MT2A | metallothionein 2A | -0.112357 |
| C3 | complement component 3 | -0.102445 |
| RPS12 | ribosomal protein S12 | -0.0889182 |
| IGF2 | insulin-like growth factor 2 | -0.0719006 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0607845 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0603008 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0549118 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0514259 |
| RPL37A | ribosomal protein L37a | -0.0500827 |
| RPS2 | ribosomal protein S2 | -0.050025 |
| TRIM26 | tripartite motif containing 26 | -0.0484265 |
| RPL11 | ribosomal protein L11 | -0.0483224 |
| MRTFA | myocardin related transcription factor A | -0.0468772 |
| BCL2L1 | BCL2-like 1 | -0.0459288 |
| RBM39 | RNA binding motif protein 39 | -0.0457408 |
| RPL9 | ribosomal protein L9 | -0.0452104 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0374128 |
| RIGI | RNA sensor RIG-I | -0.0364629 |
| B2M | beta-2-microglobulin | -0.0354277 |
| RPL26 | ribosomal protein L26 | -0.0350372 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0345754 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0338581 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0326603 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0325892 |
| PTMA | prothymosin, alpha | -0.0316522 |
| CFB | complement factor B | -0.0316096 |
| MED13L | mediator complex subunit 13-like | -0.0303546 |
| SET | SET nuclear proto-oncogene | -0.0303381 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0293123 |
| UBXN4 | UBX domain protein 4 | -0.029036 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0290295 |
| IFNGR1 | interferon gamma receptor 1 | -0.027643 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0275841 |
| PAPOLA | poly(A) polymerase alpha | -0.0273879 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0272003 |
| CUL3 | cullin 3 | -0.0269929 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0267361 |
| TMSB10 | thymosin beta 10 | -0.0267101 |
| FGA | fibrinogen alpha chain | -0.0266542 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0262628 |
| A2M | alpha-2-macroglobulin | -0.0259823 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0251655 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0243945 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0242435 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0241933 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.024076 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0239652 |
| RBM33 | RNA binding motif protein 33 | -0.02375 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0233531 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.02305 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0230249 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0229413 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0227495 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0227331 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0223461 |
| NCKAP1 | NCK-associated protein 1 | -0.0223385 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0221782 |
| LCN2 | lipocalin 2 | -0.0220737 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0219199 |
| SP100 | SP100 nuclear antigen | -0.0216841 |
| WDR43 | WD repeat domain 43 | -0.0216626 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0212214 |
| VCL | vinculin | -0.0210372 |
| IL6ST | interleukin 6 signal transducer | -0.0206949 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0206279 |
| CPE | carboxypeptidase E | -0.0203081 |
| NEMF | nuclear export mediator factor | -0.0203077 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0202957 |
| RPS17 | ribosomal protein S17 | -0.0202322 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0202032 |
| RPL7 | ribosomal protein L7 | -0.0201878 |
| CCNL1 | cyclin L1 | -0.0200107 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0199965 |
| RPS3 | ribosomal protein S3 | -0.0198497 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0198049 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0196582 |
| PEG10 | paternally expressed 10 | -0.0194238 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0193146 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0192388 |
| RPL21 | ribosomal protein L21 | -0.0192135 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.019146 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0189431 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0187742 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0186137 |
| BBX | bobby sox homolog (Drosophila) | -0.0184689 |
| JAK1 | Janus kinase 1 | -0.018393 |
| H3-3B | H3.3 histone B | -0.0182689 |
| RPL38 | ribosomal protein L38 | -0.018267 |
| TRIM25 | tripartite motif containing 25 | -0.0182331 |
| RPS5 | ribosomal protein S5 | -0.0180243 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | -0.0179951 |
| RPL36 | ribosomal protein L36 | -0.0176736 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0176298 |
| RPL10A | ribosomal protein L10a | -0.017606 |
| RPS25 | ribosomal protein S25 | -0.0176012 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0175723 |
| ALPK2 | alpha-kinase 2 | -0.0175241 |
| FBXO31 | F-box protein 31 | -0.0174111 |
