| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.10805 |
| DSPP | dentin sialophosphoprotein | 0.0637994 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0567561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0515774 |
| VEGFA | vascular endothelial growth factor A | 0.0500271 |
| EZR | ezrin | 0.0482775 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0464396 |
| KRT8 | keratin 8, type II | 0.045356 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0439121 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0420003 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0402134 |
| KRT18 | keratin 18, type I | 0.0381213 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0377241 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0371072 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0340904 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0325355 |
| ABHD2 | abhydrolase domain containing 2 | 0.0306653 |
| ONECUT3 | one cut homeobox 3 | 0.029034 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0280381 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0263515 |
| TPM3 | tropomyosin 3 | 0.0262016 |
| LMO7 | LIM domain 7 | 0.0259994 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0258665 |
| FLNB | filamin B, beta | 0.0253159 |
| NDRG1 | N-myc downstream regulated 1 | 0.0243041 |
| FAM13A | family with sequence similarity 13, member A | 0.0239693 |
| DSG2 | desmoglein 2 | 0.0232975 |
| CDCP1 | CUB domain containing protein 1 | 0.0231685 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0229963 |
| RPL3 | ribosomal protein L3 | 0.0229432 |
| ITGB4 | integrin, beta 4 | 0.0227831 |
| PLEC | plectin | 0.0226321 |
| ASPH | aspartate beta-hydroxylase | 0.0211652 |
| EHF | ets homologous factor | 0.0205731 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0202055 |
| CALB1 | calbindin 1, 28kDa | 0.0198245 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.019595 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0194383 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0191153 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0187407 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0185079 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0179935 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0179029 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0176859 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0176501 |
| CANX | calnexin | 0.0175985 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0175507 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0173711 |
| MUC17 | mucin 17, cell surface associated | 0.0168853 |
| ANXA2 | annexin A2 | 0.0167736 |
| RPL21 | ribosomal protein L21 | 0.0161916 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0161749 |
| RPS18 | ribosomal protein S18 | 0.0161683 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0159911 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0158686 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0158652 |
| HDLBP | high density lipoprotein binding protein | 0.0158075 |
| TMSB4X | thymosin beta 4, X-linked | 0.0157505 |
| AHNAK | AHNAK nucleoprotein | 0.0157343 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0157119 |
| LAMC2 | laminin, gamma 2 | 0.0155226 |
| ZNF292 | zinc finger protein 292 | 0.0154033 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0153964 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0153199 |
| PTEN | phosphatase and tensin homolog | 0.0151043 |
| FERMT1 | fermitin family member 1 | 0.0149489 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0148665 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0147223 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0146652 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0145864 |
| PGK1 | phosphoglycerate kinase 1 | 0.0145672 |
| GOLGB1 | golgin B1 | 0.0145665 |
| MXI1 | MAX interactor 1, dimerization protein | 0.01437 |
| RPL29 | ribosomal protein L29 | 0.0143339 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0140731 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0140682 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0140675 |
| PRSS3 | protease, serine, 3 | 0.0139995 |
| PHF3 | PHD finger protein 3 | 0.0139356 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0138334 |
| EGFR | epidermal growth factor receptor | 0.0136754 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0136337 |
| FOXP1 | forkhead box P1 | 0.0134987 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0133662 |
| AXIN2 | axin 2 | 0.013315 |
| RPL18 | ribosomal protein L18 | 0.0132508 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.012671 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0126139 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0125106 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0124728 |
| SH3D19 | SH3 domain containing 19 | 0.0124606 |
| INSR | insulin receptor | 0.0124203 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0122183 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0120728 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0120574 |
| ABHD17C | abhydrolase domain containing 17C | 0.0120558 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0118328 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0117984 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0117889 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0117523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.229737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142401 |
| TMSB10 | thymosin beta 10 | -0.127008 |
| VCL | vinculin | -0.107509 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107456 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102219 |
| RPL35A | ribosomal protein L35a | -0.0937837 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0801126 |
| GPHN | gephyrin | -0.0616751 |
| FTL | ferritin, light polypeptide | -0.0570666 |
| RPS6 | ribosomal protein S6 | -0.0565377 |
| RPS8 | ribosomal protein S8 | -0.0556226 |
| ACTG1 | actin gamma 1 | -0.054747 |
| RPL9 | ribosomal protein L9 | -0.0525025 |
| RPS29 | ribosomal protein S29 | -0.0519152 |
| RPLP1 | ribosomal protein, large, P1 | -0.0458337 |
| RPS24 | ribosomal protein S24 | -0.0457993 |
| IER3 | immediate early response 3 | -0.0437689 |
| RPLP2 | ribosomal protein, large, P2 | -0.0420797 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0419697 |
| RPS23 | ribosomal protein S23 | -0.0406189 |
| RPL37A | ribosomal protein L37a | -0.0403032 |
| RPL31 | ribosomal protein L31 | -0.0398433 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0383121 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0381591 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0381138 |
| RPS13 | ribosomal protein S13 | -0.0378205 |
| RPL34 | ribosomal protein L34 | -0.0373839 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0371885 |
| RPL11 | ribosomal protein L11 | -0.0370829 |
| S100P | S100 calcium binding protein P | -0.0370451 |
| RPS27A | ribosomal protein S27a | -0.03657 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0361927 |
| EGR1 | early growth response 1 | -0.0350468 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0336819 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0332492 |
| RPL38 | ribosomal protein L38 | -0.0329859 |
| AGR2 | anterior gradient 2 | -0.0315576 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0314389 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0313167 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0311321 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0306999 |
| AREG | amphiregulin | -0.0292488 |
| S100A10 | S100 calcium binding protein A10 | -0.0288641 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0288176 |
| RPS25 | ribosomal protein S25 | -0.0285882 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0284231 |
| RPL23 | ribosomal protein L23 | -0.0282701 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0279224 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0263801 |
| RPL19 | ribosomal protein L19 | -0.026218 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0260777 |
| VMP1 | vacuole membrane protein 1 | -0.0258034 |
| RPS3 | ribosomal protein S3 | -0.0256303 |
| RAB10 | RAB10, member RAS oncogene family | -0.0255399 |
| RBM39 | RNA binding motif protein 39 | -0.025046 |
| RPS19 | ribosomal protein S19 | -0.024659 |
| RPS11 | ribosomal protein S11 | -0.0246242 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0245006 |
| TRIM2 | tripartite motif containing 2 | -0.0243689 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0242997 |
| SETD5 | SET domain containing 5 | -0.024073 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.02406 |
| RPL7A | ribosomal protein L7a | -0.0238207 |
| USP53 | ubiquitin specific peptidase 53 | -0.023589 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0235882 |
| RPL36 | ribosomal protein L36 | -0.0234847 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0234365 |
| RPL28 | ribosomal protein L28 | -0.0233824 |
| RPL5 | ribosomal protein L5 | -0.0232902 |
| FBXO11 | F-box protein 11 | -0.0231821 |
| FDPS | farnesyl diphosphate synthase | -0.0229707 |
| RPS21 | ribosomal protein S21 | -0.02287 |
| GNAS | GNAS complex locus | -0.0226975 |
| ATF4 | activating transcription factor 4 | -0.0226048 |
| EPCAM | epithelial cell adhesion molecule | -0.0225722 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0222901 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0220911 |
| HMGB1 | high mobility group box 1 | -0.0218711 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0215623 |
| H3-3B | H3.3 histone B | -0.0214623 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0213759 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0213441 |
| MYO1E | myosin IE | -0.0212449 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0212408 |
| RPL37 | ribosomal protein L37 | -0.0210415 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0207452 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0207184 |
| RPS20 | ribosomal protein S20 | -0.0205225 |
| INSIG1 | insulin induced gene 1 | -0.020416 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0202671 |
| POMP | proteasome maturation protein | -0.0202251 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0201732 |
| ADIPOR2 | adiponectin receptor 2 | -0.0201583 |
| B2M | beta-2-microglobulin | -0.0199824 |
| NOP58 | NOP58 ribonucleoprotein | -0.0198771 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0198769 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.019846 |
| RPL27A | ribosomal protein L27a | -0.0197704 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0197519 |
