| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.117327 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.108989 |
| TP63 | tumor protein p63 | 0.095567 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0893224 |
| ANGPTL4 | angiopoietin-like 4 | 0.0881931 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0868501 |
| CAPRIN2 | caprin family member 2 | 0.0861462 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0800918 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0720569 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0719647 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0673792 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0660806 |
| RUNX1 | runt-related transcription factor 1 | 0.0653712 |
| RIGI | RNA sensor RIG-I | 0.0606109 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0600748 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0587694 |
| MT1X | metallothionein 1X | 0.058044 |
| RPS12 | ribosomal protein S12 | 0.0557234 |
| CADM2 | cell adhesion molecule 2 | 0.0526724 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.052216 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0518518 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.051405 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0495509 |
| HDAC9 | histone deacetylase 9 | 0.0493151 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0478271 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0474302 |
| SP100 | SP100 nuclear antigen | 0.0472704 |
| PLSCR1 | phospholipid scramblase 1 | 0.0472508 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0461314 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0450229 |
| PYGL | phosphorylase, glycogen, liver | 0.0437188 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0428366 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0405067 |
| RPL26 | ribosomal protein L26 | 0.0403402 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0402998 |
| PDE10A | phosphodiesterase 10A | 0.0385391 |
| APP | amyloid beta (A4) precursor protein | 0.0378274 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.03727 |
| RPS3 | ribosomal protein S3 | 0.0345767 |
| RPL12 | ribosomal protein L12 | 0.0344047 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0325308 |
| HLA-E | major histocompatibility complex, class I, E | 0.0322638 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.03204 |
| RNF213 | ring finger protein 213 | 0.0320309 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0317663 |
| JUN | jun proto-oncogene | 0.0309093 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0295612 |
| PCDH1 | protocadherin 1 | 0.0285465 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0284611 |
| SLK | STE20-like kinase | 0.0280637 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0278625 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0278167 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0275667 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0274047 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0272723 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0271988 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0266703 |
| MT1E | metallothionein 1E | 0.0264338 |
| HMGA1 | high mobility group AT-hook 1 | 0.026347 |
| NDRG1 | N-myc downstream regulated 1 | 0.0258462 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0257593 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0256107 |
| PMP22 | peripheral myelin protein 22 | 0.0255961 |
| TRIM56 | tripartite motif containing 56 | 0.0254425 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0250762 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0250084 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0249565 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0245101 |
| VEGFA | vascular endothelial growth factor A | 0.023666 |
| MT2A | metallothionein 2A | 0.0236253 |
| TPRG1 | tumor protein p63 regulated 1 | 0.023483 |
| DPH6 | diphthamine biosynthesis 6 | 0.0230325 |
| TNS3 | tensin 3 | 0.0223802 |
| ERCC1 | excision repair cross-complementation group 1 | 0.0222353 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0221616 |
| FMNL2 | formin-like 2 | 0.0221083 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0217379 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0216652 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0214948 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.021432 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.020957 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0207435 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0207276 |
| PRKCE | protein kinase C, epsilon | 0.0206317 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0205431 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0203919 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.02017 |
| SEC24A | SEC24 family member A | 0.020067 |
| MLPH | melanophilin | 0.019942 |
| KLF6 | Kruppel-like factor 6 | 0.0198727 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196074 |
| PLIN2 | perilipin 2 | 0.0194568 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.019348 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0193394 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0192445 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0189862 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.018952 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0188128 |
| EMP1 | epithelial membrane protein 1 | 0.0186628 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0186502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.297051 |
| PTMA | prothymosin, alpha | -0.163756 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115135 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106401 |
| TMSB10 | thymosin beta 10 | -0.097459 |
| POTEF | POTE ankyrin domain family, member F | -0.0879677 |
| CENPF | centromere protein F, 350/400kDa | -0.0849827 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0745541 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0729562 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0710052 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.064267 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0617419 |
| ACTG1 | actin gamma 1 | -0.0612159 |
| MKI67 | marker of proliferation Ki-67 | -0.0579484 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0509667 |
| FTL | ferritin, light polypeptide | -0.0478132 |
| TXNRD1 | thioredoxin reductase 1 | -0.0466179 |
| SRGN | serglycin | -0.045504 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0454744 |
| ZNF217 | zinc finger protein 217 | -0.043867 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0437812 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0436356 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0427897 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.041418 |
| ECT2 | epithelial cell transforming 2 | -0.040419 |
| ANLN | anillin, actin binding protein | -0.0403465 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0397796 |
| HDLBP | high density lipoprotein binding protein | -0.0395959 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0392934 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0390572 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0381713 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0378493 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0376701 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0375618 |
| AHNAK | AHNAK nucleoprotein | -0.0374397 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0373834 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0373057 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0370308 |
| CMIP | c-Maf inducing protein | -0.036423 |
| RPL35A | ribosomal protein L35a | -0.0364221 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0362823 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0362621 |
| RBM39 | RNA binding motif protein 39 | -0.0351481 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0334849 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0330957 |
| DIAPH3 | diaphanous-related formin 3 | -0.0330822 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0327633 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.031636 |
| SMAD3 | SMAD family member 3 | -0.0315885 |
| YBX1 | Y box binding protein 1 | -0.0315436 |
| OGA | O-GlcNAcase | -0.0311113 |
| RCOR1 | REST corepressor 1 | -0.0308349 |
| RBM25 | RNA binding motif protein 25 | -0.0307923 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0303773 |
| WASF2 | WAS protein family, member 2 | -0.0301064 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0297686 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0294707 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0294141 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0294 |
| TPX2 | TPX2, microtubule-associated | -0.028589 |
| WDR45B | WD repeat domain 45B | -0.0279847 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0279403 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0278738 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0278406 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.02778 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0277139 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0277019 |
| EZR | ezrin | -0.0274977 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0271114 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.027086 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.026473 |
| MAP4 | microtubule-associated protein 4 | -0.0264628 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0260303 |
| RPL38 | ribosomal protein L38 | -0.0259568 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0259021 |
| VIM | vimentin | -0.0258945 |
| VCL | vinculin | -0.0255641 |
| USP34 | ubiquitin specific peptidase 34 | -0.0254086 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0253283 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0253136 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0252939 |
| PFN1 | profilin 1 | -0.0252743 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0252383 |
| TMEM123 | transmembrane protein 123 | -0.0249094 |
| GOLGA4 | golgin A4 | -0.0248543 |
| TOP1 | topoisomerase (DNA) I | -0.0248255 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0246223 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0245102 |
| BRD4 | bromodomain containing 4 | -0.0243212 |
| KIF14 | kinesin family member 14 | -0.0242087 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0241639 |
| CLTC | clathrin, heavy chain (Hc) | -0.0240882 |
| XPO1 | exportin 1 | -0.0240721 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0238885 |
| FNIP1 | folliculin interacting protein 1 | -0.0236654 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0235257 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0234777 |
| CKAP2 | cytoskeleton associated protein 2 | -0.023385 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0231255 |
| RAI1 | retinoic acid induced 1 | -0.0230534 |
