| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.17987 |
| PM20D1 | peptidase M20 domain containing 1 | 0.146212 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.107264 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.106174 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0932719 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0818056 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0774261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0729851 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0709998 |
| TXNRD1 | thioredoxin reductase 1 | 0.0701813 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0694308 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.06403 |
| FAM107B | family with sequence similarity 107, member B | 0.0616267 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0607763 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0602629 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0601231 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0600627 |
| KYNU | kynureninase | 0.0594816 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0588914 |
| SVIL | supervillin | 0.0580355 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.056184 |
| GLIS3 | GLIS family zinc finger 3 | 0.0549773 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0525913 |
| EGFR | epidermal growth factor receptor | 0.052195 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0509827 |
| MCL1 | myeloid cell leukemia 1 | 0.0505528 |
| BICC1 | BicC family RNA binding protein 1 | 0.0479963 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0479358 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0464387 |
| NRG1 | neuregulin 1 | 0.0448535 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437578 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0432764 |
| USP34 | ubiquitin specific peptidase 34 | 0.042439 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0422582 |
| PDLIM5 | PDZ and LIM domain 5 | 0.041318 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0412784 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0410358 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0397032 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0390006 |
| MRTFA | myocardin related transcription factor A | 0.0387858 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0383916 |
| MYOF | myoferlin | 0.0379705 |
| SMAD2 | SMAD family member 2 | 0.0376187 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0374506 |
| RAB31 | RAB31, member RAS oncogene family | 0.037289 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0365775 |
| NTN4 | netrin 4 | 0.0362224 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0357716 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0339838 |
| FMNL2 | formin-like 2 | 0.0339232 |
| CMIP | c-Maf inducing protein | 0.0337592 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0337013 |
| ZNF638 | zinc finger protein 638 | 0.0335933 |
| PTK2 | protein tyrosine kinase 2 | 0.0335345 |
| ATXN1 | ataxin 1 | 0.0332994 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0332023 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0330965 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0329913 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0327579 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0324521 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0321663 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0316835 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0309812 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0306747 |
| SLC38A2 | solute carrier family 38, member 2 | 0.030396 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.030325 |
| AHR | aryl hydrocarbon receptor | 0.0302252 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0301395 |
| BMP6 | bone morphogenetic protein 6 | 0.0297183 |
| FLNA | filamin A, alpha | 0.0287063 |
| RHOA | ras homolog family member A | 0.0283083 |
| COPA | coatomer protein complex, subunit alpha | 0.0281867 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0278151 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0277802 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0277625 |
| WDR59 | WD repeat domain 59 | 0.0269573 |
| RPL35A | ribosomal protein L35a | 0.0268961 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0266676 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0266052 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265938 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0263861 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0260932 |
| HLA-E | major histocompatibility complex, class I, E | 0.0259621 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0259132 |
| BRD2 | bromodomain containing 2 | 0.0259073 |
| TPD52 | tumor protein D52 | 0.0258834 |
| RAB10 | RAB10, member RAS oncogene family | 0.0256878 |
| EXOC6B | exocyst complex component 6B | 0.0254532 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0251383 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0249585 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0248389 |
| INTS6 | integrator complex subunit 6 | 0.0247435 |
| SPAG9 | sperm associated antigen 9 | 0.0246957 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0246582 |
| CCNY | cyclin Y | 0.0244896 |
| SMAD3 | SMAD family member 3 | 0.0244592 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.024444 |
| SQSTM1 | sequestosome 1 | 0.0243146 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0243069 |
| SIK3 | SIK family kinase 3 | 0.0240944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.152798 |
| VIM | vimentin | -0.131989 |
| TMSB10 | thymosin beta 10 | -0.12199 |
| MT2A | metallothionein 2A | -0.121433 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0854152 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.081553 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644092 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0562348 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0435326 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0395363 |
| RPL23 | ribosomal protein L23 | -0.0380285 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0330244 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0316919 |
| EFNA5 | ephrin-A5 | -0.0312174 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0302372 |
| MAP1B | microtubule-associated protein 1B | -0.028045 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0272801 |
| PYGL | phosphorylase, glycogen, liver | -0.0271056 |
| FLNB | filamin B, beta | -0.0269741 |
| RPL36AL | ribosomal protein L36a-like | -0.0266407 |
| TPI1 | triosephosphate isomerase 1 | -0.0265099 |
| TPM3 | tropomyosin 3 | -0.0262497 |
| EHBP1 | EH domain binding protein 1 | -0.0261018 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0257642 |
| HMGA1 | high mobility group AT-hook 1 | -0.02552 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0248021 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0244347 |
| TPM4 | tropomyosin 4 | -0.0236605 |
| PFN1 | profilin 1 | -0.0236524 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0233189 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0228962 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0227633 |
| KIF5B | kinesin family member 5B | -0.0222758 |
| S100A6 | S100 calcium binding protein A6 | -0.0218626 |
| NHSL1 | NHS-like 1 | -0.0217019 |
| KLF6 | Kruppel-like factor 6 | -0.021597 |
| GNAS | GNAS complex locus | -0.0212566 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0211953 |
| RPL18 | ribosomal protein L18 | -0.0204827 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0204808 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0203184 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0202017 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0201068 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0198312 |
| RPS12 | ribosomal protein S12 | -0.0197297 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0195552 |
| EGR1 | early growth response 1 | -0.019252 |
| RPS27 | ribosomal protein S27 | -0.0190097 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0187142 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0186075 |
| STC1 | stanniocalcin 1 | -0.0183674 |
| RPS3 | ribosomal protein S3 | -0.0182114 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0180933 |
| AHNAK | AHNAK nucleoprotein | -0.0179548 |
| RPL36 | ribosomal protein L36 | -0.0178958 |
| AK1 | adenylate kinase 1 | -0.0178785 |
| GTPBP4 | GTP binding protein 4 | -0.0176611 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0175494 |
| GPC6 | glypican 6 | -0.0175255 |
| FTL | ferritin, light polypeptide | -0.017502 |
| CBX3 | chromobox homolog 3 | -0.0174537 |
| MIS18BP1 | MIS18 binding protein 1 | -0.017452 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0173969 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0172192 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0171462 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0170223 |
| RAI1 | retinoic acid induced 1 | -0.0169519 |
| ASPH | aspartate beta-hydroxylase | -0.0169255 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0169189 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0163603 |
| CALR | calreticulin | -0.0163159 |
| ARF4 | ADP-ribosylation factor 4 | -0.0162794 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.0162277 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.016081 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0160765 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.0160741 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0159093 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0158281 |
| NDRG1 | N-myc downstream regulated 1 | -0.0155519 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0154005 |
| RPS19 | ribosomal protein S19 | -0.0152581 |
| RPLP0 | ribosomal protein, large, P0 | -0.0151797 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0151118 |
| GOLGA4 | golgin A4 | -0.0151097 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0150157 |
| H1-0 | H1.0 linker histone | -0.0149857 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0149527 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0148272 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0147931 |
| LMNA | lamin A/C | -0.0147904 |
| ACTG1 | actin gamma 1 | -0.0146611 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0146538 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0145633 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0144456 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0143111 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0142669 |
| TAGLN2 | transgelin 2 | -0.0142634 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0142563 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0141727 |
| LAMB1 | laminin, beta 1 | -0.0141587 |
