| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.179878 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.157962 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.148707 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.143908 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.113827 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.11239 |
| LAMC2 | laminin, gamma 2 | 0.0812357 |
| LAMA4 | laminin, alpha 4 | 0.0792319 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0699752 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0691556 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0649045 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0624745 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0613478 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0613075 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0594827 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0577452 |
| SVIL | supervillin | 0.0567886 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0558628 |
| STC1 | stanniocalcin 1 | 0.0552499 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0550638 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0518586 |
| AFDN | afadin, adherens junction formation factor | 0.0508756 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0508606 |
| RBM39 | RNA binding motif protein 39 | 0.0504101 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0499634 |
| HELZ | helicase with zinc finger | 0.0493445 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0485071 |
| XPO1 | exportin 1 | 0.0484468 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0475673 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0474607 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0473216 |
| MUC16 | mucin 16, cell surface associated | 0.0464985 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0456259 |
| LMO7 | LIM domain 7 | 0.045514 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0448834 |
| RPS12 | ribosomal protein S12 | 0.0442881 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0440141 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0438802 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0434083 |
| MCL1 | myeloid cell leukemia 1 | 0.0425431 |
| RASA2 | RAS p21 protein activator 2 | 0.0424898 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0416257 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0415572 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0409034 |
| EGFR | epidermal growth factor receptor | 0.0407087 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0402494 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0394249 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0391042 |
| JMJD1C | jumonji domain containing 1C | 0.0387175 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0385766 |
| SON | SON DNA binding protein | 0.0384322 |
| SFPQ | splicing factor proline/glutamine-rich | 0.03838 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0374133 |
| ATOSA | atos homolog A | 0.0372373 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0370181 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.036915 |
| SKIL | SKI-like proto-oncogene | 0.0368327 |
| IRS2 | insulin receptor substrate 2 | 0.0362355 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0354507 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | 0.035314 |
| PDE10A | phosphodiesterase 10A | 0.0348481 |
| SUMF1 | sulfatase modifying factor 1 | 0.0344805 |
| RBM47 | RNA binding motif protein 47 | 0.0339675 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0334799 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0333779 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0331624 |
| KLF6 | Kruppel-like factor 6 | 0.0330227 |
| GSK3B | glycogen synthase kinase 3 beta | 0.032951 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0327715 |
| MED15 | mediator complex subunit 15 | 0.0326844 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0325148 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0320178 |
| FNIP1 | folliculin interacting protein 1 | 0.0318883 |
| FRMD4A | FERM domain containing 4A | 0.0308642 |
| FER | fer (fps/fes related) tyrosine kinase | 0.030753 |
| FAM13A | family with sequence similarity 13, member A | 0.030717 |
| ABHD17C | abhydrolase domain containing 17C | 0.030704 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0306109 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0305578 |
| SMYD3 | SET and MYND domain containing 3 | 0.030555 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0303847 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0301709 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0300948 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0298213 |
| USP34 | ubiquitin specific peptidase 34 | 0.0296216 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0295974 |
| FMNL2 | formin-like 2 | 0.0294343 |
| TULP4 | tubby like protein 4 | 0.0293916 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0293829 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0292651 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0291373 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0290991 |
| CUX1 | cut-like homeobox 1 | 0.0290655 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0288409 |
| CCNY | cyclin Y | 0.0285358 |
| PHIP | pleckstrin homology domain interacting protein | 0.0284456 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0282312 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0280741 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0276938 |
| ETNK1 | ethanolamine kinase 1 | 0.0276149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.130722 |
| PTMA | prothymosin, alpha | -0.118986 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.084446 |
| B2M | beta-2-microglobulin | -0.0772028 |
| PGK1 | phosphoglycerate kinase 1 | -0.0682993 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0673436 |
| RPS8 | ribosomal protein S8 | -0.0628738 |
| IER3 | immediate early response 3 | -0.0617446 |
| UBC | ubiquitin C | -0.0595161 |
| RPL19 | ribosomal protein L19 | -0.055492 |
| TMSB10 | thymosin beta 10 | -0.0554887 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0540854 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.053732 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.053064 |
| CANX | calnexin | -0.0529484 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0522098 |
| RPL26 | ribosomal protein L26 | -0.0521821 |
| LDHA | lactate dehydrogenase A | -0.0511762 |
| IGF2 | insulin-like growth factor 2 | -0.0491106 |
| ENO1 | enolase 1, (alpha) | -0.0484102 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0471412 |
| FTL | ferritin, light polypeptide | -0.0467006 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0464315 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0448875 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0443386 |
| MSI2 | musashi RNA-binding protein 2 | -0.0440444 |
| RPLP1 | ribosomal protein, large, P1 | -0.0438876 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0438202 |
| HLA-B | major histocompatibility complex, class I, B | -0.0437928 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0426976 |
| BPTF | bromodomain PHD finger transcription factor | -0.0409336 |
| HMGB1 | high mobility group box 1 | -0.0407713 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0397922 |
| TNRC6B | trinucleotide repeat containing 6B | -0.039669 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0390261 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0388409 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0371336 |
| MT2A | metallothionein 2A | -0.0370743 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0369312 |
| CALR | calreticulin | -0.0366024 |
| CDK6 | cyclin-dependent kinase 6 | -0.0365046 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.036186 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0360246 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0358146 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0350422 |
| RPS11 | ribosomal protein S11 | -0.0350069 |
| SQSTM1 | sequestosome 1 | -0.0342066 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0340011 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0337386 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0333622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0331356 |
| RPLP2 | ribosomal protein, large, P2 | -0.03309 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0327908 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0326371 |
| STX8 | syntaxin 8 | -0.0317607 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0317046 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0316364 |
| RPS25 | ribosomal protein S25 | -0.0314946 |
| FAT1 | FAT atypical cadherin 1 | -0.030922 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0305326 |
| TAOK1 | TAO kinase 1 | -0.0302546 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302529 |
| FAM107B | family with sequence similarity 107, member B | -0.0301514 |
| PKP4 | plakophilin 4 | -0.0298349 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.029345 |
| ASPH | aspartate beta-hydroxylase | -0.0293237 |
| RBM25 | RNA binding motif protein 25 | -0.0292698 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -0.0291236 |
| MED13L | mediator complex subunit 13-like | -0.0288783 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0287982 |
| PERP | PERP, TP53 apoptosis effector | -0.028596 |
| AUTS2 | autism susceptibility candidate 2 | -0.0285419 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0284457 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0283363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.028257 |
| SFTPA2 | surfactant protein A2 | -0.0282388 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0278212 |
| WASF2 | WAS protein family, member 2 | -0.0278148 |
| CTBP2 | C-terminal binding protein 2 | -0.0277965 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0274014 |
| MUC13 | mucin 13, cell surface associated | -0.0273865 |
| RPL38 | ribosomal protein L38 | -0.0273594 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0272694 |
| H3-3B | H3.3 histone B | -0.0272483 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0272078 |
| SYT1 | synaptotagmin I | -0.0268821 |
| FHL2 | four and a half LIM domains 2 | -0.0267692 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0267336 |
| CD2AP | CD2-associated protein | -0.0266533 |
| ANGPTL4 | angiopoietin-like 4 | -0.0263333 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0262305 |
| RPL37A | ribosomal protein L37a | -0.0261432 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0260255 |
| CDK13 | cyclin-dependent kinase 13 | -0.0260185 |
| RPS27 | ribosomal protein S27 | -0.0259026 |
| RPL11 | ribosomal protein L11 | -0.0258714 |
| TPX2 | TPX2, microtubule-associated | -0.0256536 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0252856 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0252072 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.024947 |
