| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.113036 |
| VEGFA | vascular endothelial growth factor A | 0.105048 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.101387 |
| PLEC | plectin | 0.0998607 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0958473 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0883287 |
| FN1 | fibronectin 1 | 0.0837443 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0682611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.06722 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.066034 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0590695 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0575128 |
| MSN | moesin | 0.0544962 |
| NDRG1 | N-myc downstream regulated 1 | 0.0519978 |
| FAM13A | family with sequence similarity 13, member A | 0.0515796 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0486713 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0481062 |
| LAMB3 | laminin, beta 3 | 0.0456286 |
| DSPP | dentin sialophosphoprotein | 0.0449571 |
| NAV2 | neuron navigator 2 | 0.0418874 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0417169 |
| DTNA | dystrobrevin, alpha | 0.039775 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0372712 |
| RPS6 | ribosomal protein S6 | 0.0364258 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0363461 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0354759 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0352344 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0352202 |
| CCNL1 | cyclin L1 | 0.0335525 |
| RNF145 | ring finger protein 145 | 0.0324128 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0323592 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0321381 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0319181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0316295 |
| DUSP10 | dual specificity phosphatase 10 | 0.0308697 |
| COPA | coatomer protein complex, subunit alpha | 0.0287247 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0283583 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0282134 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0276763 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264605 |
| ANKRD11 | ankyrin repeat domain 11 | 0.026421 |
| RPL3 | ribosomal protein L3 | 0.0263859 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0259527 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0258791 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0256663 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0253423 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0252859 |
| RPL29 | ribosomal protein L29 | 0.025045 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0248204 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0247437 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0242814 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0240937 |
| FOSL1 | FOS-like antigen 1 | 0.0240856 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0234273 |
| IRF6 | interferon regulatory factor 6 | 0.0230996 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0228365 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0228095 |
| MSI2 | musashi RNA-binding protein 2 | 0.0228016 |
| EZR | ezrin | 0.0227854 |
| FLNA | filamin A, alpha | 0.0225772 |
| HYOU1 | hypoxia up-regulated 1 | 0.0223826 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0223781 |
| MEF2A | myocyte enhancer factor 2A | 0.0218077 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0216539 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0215692 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0214613 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0212091 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0208163 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0207894 |
| MYO10 | myosin X | 0.0207184 |
| PTK2 | protein tyrosine kinase 2 | 0.020695 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0206681 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0206629 |
| MKRN1 | makorin ring finger protein 1 | 0.0205287 |
| TPM3 | tropomyosin 3 | 0.0201041 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0200383 |
| RPL13A | ribosomal protein L13a | 0.0199432 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0199344 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0198834 |
| RBM39 | RNA binding motif protein 39 | 0.0198156 |
| MAP1B | microtubule-associated protein 1B | 0.0194471 |
| FLNC | filamin C, gamma | 0.0194454 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0193823 |
| HELZ | helicase with zinc finger | 0.0191181 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0189347 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0188549 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0187514 |
| ATP11B | ATPase, class VI, type 11B | 0.0187507 |
| MEF2D | myocyte enhancer factor 2D | 0.0186887 |
| JUP | junction plakoglobin | 0.018569 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0185209 |
| MATR3 | matrin 3 | 0.0184888 |
| SRPK2 | SRSF protein kinase 2 | 0.0184822 |
| RPS20 | ribosomal protein S20 | 0.0182917 |
| UPP1 | uridine phosphorylase 1 | 0.0182044 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0181565 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0180654 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.017871 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0176558 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0175305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.24576 |
| UBC | ubiquitin C | -0.222217 |
| TMSB10 | thymosin beta 10 | -0.209483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162207 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.14551 |
| S100A6 | S100 calcium binding protein A6 | -0.143627 |
| ASPH | aspartate beta-hydroxylase | -0.139057 |
| PTMA | prothymosin, alpha | -0.123308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.102112 |
| ENO1 | enolase 1, (alpha) | -0.0923246 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0876735 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0870663 |
| ACTG1 | actin gamma 1 | -0.0816483 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0716337 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0691366 |
| RPS27A | ribosomal protein S27a | -0.0673096 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0671879 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0669551 |
| LMO7 | LIM domain 7 | -0.0668444 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.065947 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0641365 |
| AHNAK | AHNAK nucleoprotein | -0.0624393 |
| EPCAM | epithelial cell adhesion molecule | -0.0580326 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0567829 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.055889 |
| S100A10 | S100 calcium binding protein A10 | -0.0550281 |
| MT2A | metallothionein 2A | -0.0549534 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0545996 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0514612 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.050761 |
| RPL34 | ribosomal protein L34 | -0.0502155 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0488728 |
| SDC4 | syndecan 4 | -0.0475598 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0455433 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.045527 |
| HMGB2 | high mobility group box 2 | -0.0445048 |
| CD2AP | CD2-associated protein | -0.0435017 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0411327 |
| TMSB4X | thymosin beta 4, X-linked | -0.0402326 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0400351 |
| VCL | vinculin | -0.0387727 |
| TMEM263 | transmembrane protein 263 | -0.0384433 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0382918 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0382571 |
| RPS3 | ribosomal protein S3 | -0.0381332 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0380134 |
| CCNI | cyclin I | -0.0374673 |
| FTL | ferritin, light polypeptide | -0.0373984 |
| TXNIP | thioredoxin interacting protein | -0.0372845 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0371692 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0361516 |
| RPL23 | ribosomal protein L23 | -0.0355896 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0354188 |
| RPS24 | ribosomal protein S24 | -0.0351943 |
| RPL9 | ribosomal protein L9 | -0.0346256 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0346079 |
| RACK1 | receptor for activated C kinase 1 | -0.0345599 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0340672 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0340424 |
| CCND1 | cyclin D1 | -0.0335101 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0328947 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0326832 |
| HLA-B | major histocompatibility complex, class I, B | -0.0320171 |
| RPS8 | ribosomal protein S8 | -0.031024 |
| SP100 | SP100 nuclear antigen | -0.0305937 |
| ETV6 | ets variant 6 | -0.0305515 |
| LOC112694756 | uncharaterized LOC112694756 | -0.030548 |
| SQSTM1 | sequestosome 1 | -0.0305339 |
| OSMR | oncostatin M receptor | -0.0304647 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0301293 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.030096 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.030082 |
| CD9 | CD9 molecule | -0.0297002 |
| PLSCR1 | phospholipid scramblase 1 | -0.0296385 |
| CALU | calumenin | -0.0296078 |
| KRT7 | keratin 7, type II | -0.0295323 |
| LDHA | lactate dehydrogenase A | -0.0288175 |
| MX2 | MX dynamin-like GTPase 2 | -0.028785 |
| DUSP6 | dual specificity phosphatase 6 | -0.0286853 |
| HLA-E | major histocompatibility complex, class I, E | -0.0286654 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0286091 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0285893 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0284639 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0284189 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281013 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0280396 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0274937 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0273377 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.027142 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0265253 |
| KLF6 | Kruppel-like factor 6 | -0.0263327 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0260115 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0258379 |
| CD63 | CD63 molecule | -0.0252368 |
| MX1 | MX dynamin-like GTPase 1 | -0.0252218 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.024959 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0248477 |
| RPL32 | ribosomal protein L32 | -0.0245703 |
| TPI1 | triosephosphate isomerase 1 | -0.0244268 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0241973 |
