| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.124316 |
| KYNU | kynureninase | 0.0975145 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0944186 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0851201 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0782449 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0680277 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0668208 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0632722 |
| PDE10A | phosphodiesterase 10A | 0.0624403 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0587485 |
| FMNL2 | formin-like 2 | 0.058388 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0579517 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0565136 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0555054 |
| PCBP2 | poly(rC) binding protein 2 | 0.0552462 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0547905 |
| VCL | vinculin | 0.052488 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0511432 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0495735 |
| SMAD2 | SMAD family member 2 | 0.0488456 |
| INTS6 | integrator complex subunit 6 | 0.0485862 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0441726 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0435225 |
| SPAG9 | sperm associated antigen 9 | 0.0418871 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0414887 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0409045 |
| MYOF | myoferlin | 0.0400189 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0397545 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0394429 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0384577 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0384392 |
| AUTS2 | autism susceptibility candidate 2 | 0.038414 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0381895 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0381092 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0367811 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0364827 |
| FLNA | filamin A, alpha | 0.0359848 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0347538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.034245 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0336259 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0332574 |
| BMP6 | bone morphogenetic protein 6 | 0.0329628 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0329622 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0327133 |
| EPHA4 | EPH receptor A4 | 0.0303548 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0302226 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0301095 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0297829 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0292373 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0291895 |
| GRAMD1B | GRAM domain containing 1B | 0.0289632 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0289215 |
| POTEF | POTE ankyrin domain family, member F | 0.0280809 |
| DST | dystonin | 0.0280058 |
| CTBP2 | C-terminal binding protein 2 | 0.0279056 |
| FNIP1 | folliculin interacting protein 1 | 0.0272983 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0264436 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.026357 |
| HDAC4 | histone deacetylase 4 | 0.0251403 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0246987 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0246805 |
| LAMA5 | laminin, alpha 5 | 0.0244045 |
| OXSR1 | oxidative stress responsive 1 | 0.0241387 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0239675 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0239244 |
| IRS2 | insulin receptor substrate 2 | 0.0226885 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0226557 |
| ANTXR1 | anthrax toxin receptor 1 | 0.022577 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0222786 |
| ATXN1 | ataxin 1 | 0.0222342 |
| EZR | ezrin | 0.0221845 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0219796 |
| AADAC | arylacetamide deacetylase | 0.0219496 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0218216 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0216867 |
| NUP58 | nucleoporin 58 | 0.0215933 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0214914 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0213646 |
| SQSTM1 | sequestosome 1 | 0.0213638 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0213523 |
| COPA | coatomer protein complex, subunit alpha | 0.0213294 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211474 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0207365 |
| HELZ | helicase with zinc finger | 0.0207216 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0204842 |
| BSG | basigin (Ok blood group) | 0.020453 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0204172 |
| FAM168A | family with sequence similarity 168, member A | 0.0202066 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0202025 |
| FOXK1 | forkhead box K1 | 0.0201025 |
| RNF145 | ring finger protein 145 | 0.0198599 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0197881 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0197392 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0195872 |
| LDHA | lactate dehydrogenase A | 0.0194436 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0193697 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0192589 |
| RAD51B | RAD51 paralog B | 0.0192098 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0190457 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0190126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.165903 |
| EFNA5 | ephrin-A5 | -0.125245 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.120514 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.112784 |
| VIM | vimentin | -0.108623 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10225 |
| PTMA | prothymosin, alpha | -0.0939288 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0887711 |
| TXNRD1 | thioredoxin reductase 1 | -0.0850512 |
| FN1 | fibronectin 1 | -0.0794781 |
| GDA | guanine deaminase | -0.077785 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0755108 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0743051 |
| RPS6 | ribosomal protein S6 | -0.0709614 |
| CTSL | cathepsin L | -0.0680371 |
| TMSB10 | thymosin beta 10 | -0.0633375 |
| RPLP1 | ribosomal protein, large, P1 | -0.0622777 |
| RPL26 | ribosomal protein L26 | -0.0620983 |
| RPS24 | ribosomal protein S24 | -0.0614816 |
| SMYD3 | SET and MYND domain containing 3 | -0.0601235 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0587131 |
| RPL37A | ribosomal protein L37a | -0.0573199 |
| PTGR1 | prostaglandin reductase 1 | -0.0572154 |
| STC1 | stanniocalcin 1 | -0.0567343 |
| RPL36A | ribosomal protein L36a | -0.0564236 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0556331 |
| RPL12 | ribosomal protein L12 | -0.0546327 |
| RPL31 | ribosomal protein L31 | -0.049926 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.04952 |
| RGS2 | regulator of G-protein signaling 2 | -0.0494483 |
| RPS12 | ribosomal protein S12 | -0.0486074 |
| HLA-B | major histocompatibility complex, class I, B | -0.0483939 |
| RPS8 | ribosomal protein S8 | -0.0469431 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0464018 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0455675 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0453842 |
| OSMR | oncostatin M receptor | -0.045308 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.045015 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0440004 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0431663 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0429864 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0428372 |
| BMERB1 | bMERB domain containing 1 | -0.0426503 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0421439 |
| RPL38 | ribosomal protein L38 | -0.0419179 |
| RPL35A | ribosomal protein L35a | -0.0418434 |
| CDH13 | cadherin 13 | -0.0415985 |
| NRCAM | neuronal cell adhesion molecule | -0.0415649 |
| RPS27A | ribosomal protein S27a | -0.0411407 |
| SRGN | serglycin | -0.0400077 |
| INHBA | inhibin, beta A | -0.039982 |
| RPL19 | ribosomal protein L19 | -0.0395896 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0390506 |
| S100A6 | S100 calcium binding protein A6 | -0.0389287 |
| TENM3 | teneurin transmembrane protein 3 | -0.0379863 |
| MFF | mitochondrial fission factor | -0.0379656 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0371504 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0371035 |
| RPL34 | ribosomal protein L34 | -0.0370479 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0365253 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0358896 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0356145 |
| RPS27 | ribosomal protein S27 | -0.035376 |
| RPS19 | ribosomal protein S19 | -0.0353358 |
| TBXT | T-box transcription factor T | -0.0349303 |
| RPL9 | ribosomal protein L9 | -0.0344901 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0343922 |
| RPS3 | ribosomal protein S3 | -0.0337555 |
| RPS29 | ribosomal protein S29 | -0.0335771 |
| RPL37 | ribosomal protein L37 | -0.0335688 |
| RPS21 | ribosomal protein S21 | -0.0333677 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0333225 |
| NCKAP5 | NCK-associated protein 5 | -0.0325206 |
| PALLD | palladin, cytoskeletal associated protein | -0.0322845 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0322501 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0321293 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0315669 |
| RPS2 | ribosomal protein S2 | -0.0314716 |
| B2M | beta-2-microglobulin | -0.031429 |
| FOXC1 | forkhead box C1 | -0.0311629 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311249 |
| RPLP0 | ribosomal protein, large, P0 | -0.029828 |
| TNPO1 | transportin 1 | -0.0294091 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0293613 |
| RPS13 | ribosomal protein S13 | -0.0293554 |
| CRLF2 | cytokine receptor-like factor 2 | -0.0290904 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0283176 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0283102 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0281565 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0281169 |
| RPS23 | ribosomal protein S23 | -0.0280182 |
| KIAA0825 | KIAA0825 | -0.0275667 |
| RPS16 | ribosomal protein S16 | -0.0272379 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0268897 |
| SEPTIN10 | septin 10 | -0.0266913 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0265743 |
| TMSB4X | thymosin beta 4, X-linked | -0.0263389 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0260055 |
| GPRIN3 | GPRIN family member 3 | -0.0259463 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0258745 |
