| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
175 genes differentially expressed following the Rapamycin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.149348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.138284 |
| EXT1 | exostosin glycosyltransferase 1 | 0.134238 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.120113 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.118961 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.114069 |
| EGFR | epidermal growth factor receptor | 0.102461 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.101179 |
| LMO7 | LIM domain 7 | 0.0994716 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.093945 |
| JMJD1C | jumonji domain containing 1C | 0.090823 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0885388 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0880811 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0827285 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0820069 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0783451 |
| USP34 | ubiquitin specific peptidase 34 | 0.0779281 |
| MT2A | metallothionein 2A | 0.0756756 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0746179 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0721529 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0658803 |
| COL5A2 | collagen, type V, alpha 2 | 0.0654455 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0612421 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0570894 |
| NDRG1 | N-myc downstream regulated 1 | 0.0566337 |
| CEP350 | centrosomal protein 350kDa | 0.0559573 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0548082 |
| GOLGA4 | golgin A4 | 0.0543591 |
| RPLP1 | ribosomal protein, large, P1 | 0.0539354 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0520846 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0503988 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0492515 |
| FMNL2 | formin-like 2 | 0.0482356 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0458717 |
| NAV2 | neuron navigator 2 | 0.0443486 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.043801 |
| FER | fer (fps/fes related) tyrosine kinase | 0.042351 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0416395 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0415418 |
| VMP1 | vacuole membrane protein 1 | 0.0408227 |
| MYO10 | myosin X | 0.0354021 |
| HLA-A | major histocompatibility complex, class I, A | 0.0339339 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0336485 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0326102 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0319549 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0314044 |
| PTK2 | protein tyrosine kinase 2 | 0.0291204 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0288469 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0283323 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0268795 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.026799 |
| EFNA5 | ephrin-A5 | 0.0249562 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0245764 |
| INHBA | inhibin, beta A | 0.0242498 |
| RPL35A | ribosomal protein L35a | 0.0233191 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0218935 |
| CUX1 | cut-like homeobox 1 | 0.0214584 |
| ENO1 | enolase 1, (alpha) | 0.0211809 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0211552 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.020506 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0195262 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0193118 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0172333 |
| OSMR | oncostatin M receptor | 0.0169079 |
| ASPH | aspartate beta-hydroxylase | 0.0165218 |
| PDE10A | phosphodiesterase 10A | 0.0164582 |
| BMERB1 | bMERB domain containing 1 | 0.0161913 |
| UTRN | utrophin | 0.0147624 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0141068 |
| TXNRD1 | thioredoxin reductase 1 | 0.0136392 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0132536 |
| TCF12 | transcription factor 12 | 0.0127015 |
| HMGA2 | high mobility group AT-hook 2 | 0.0126355 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0105097 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00977519 |
| RPL37A | ribosomal protein L37a | 0.00936664 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00894411 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00841167 |
| BBX | bobby sox homolog (Drosophila) | 0.00828715 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00807329 |
| AOPEP | aminopeptidase O (putative) | 0.00794573 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00774932 |
| ZNF292 | zinc finger protein 292 | 0.00659841 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00631496 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00604089 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00422107 |
| SBF2 | SET binding factor 2 | 0.00327262 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00283306 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.00215526 |
| MYOF | myoferlin | 0.00189065 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00187206 |
| RPL31 | ribosomal protein L31 | 4.27952E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.374663 |
| FN1 | fibronectin 1 | -0.183411 |
| UBC | ubiquitin C | -0.165358 |
| VIM | vimentin | -0.132672 |
| PTMA | prothymosin, alpha | -0.114022 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.110487 |
| DST | dystonin | -0.108172 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.106276 |
| RTN4 | reticulon 4 | -0.0934083 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0914178 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.081822 |
| LDHA | lactate dehydrogenase A | -0.0801489 |
| TMSB10 | thymosin beta 10 | -0.0729878 |
| GPHN | gephyrin | -0.0713941 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0706803 |
| NUP58 | nucleoporin 58 | -0.0681165 |
| PGK1 | phosphoglycerate kinase 1 | -0.0680978 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0663238 |
| SETD5 | SET domain containing 5 | -0.0657607 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0647304 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0632594 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0618041 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0601598 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0595645 |
| RPS27A | ribosomal protein S27a | -0.0588639 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0557383 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.05345 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0505006 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0496292 |
| CCNI | cyclin I | -0.048923 |
| PKM | pyruvate kinase, muscle | -0.0487279 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0479154 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0469421 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.046867 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0420494 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0392055 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0388783 |
| PARD3 | par-3 family cell polarity regulator | -0.037935 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0373596 |
| GPC6 | glypican 6 | -0.0367202 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0358608 |
| RPS6 | ribosomal protein S6 | -0.0347666 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0342276 |
| ACTN4 | actinin, alpha 4 | -0.0333017 |
| SRPK2 | SRSF protein kinase 2 | -0.0320931 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0314884 |
| RLF | rearranged L-myc fusion | -0.0311562 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0307622 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0307367 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0291673 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0286264 |
| RPL23 | ribosomal protein L23 | -0.0285359 |
| SMYD3 | SET and MYND domain containing 3 | -0.0255582 |
| RPS3 | ribosomal protein S3 | -0.0246951 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0242344 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0231526 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.022057 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0212491 |
| ACTG1 | actin gamma 1 | -0.0206606 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0202602 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0188068 |
| ANXA2 | annexin A2 | -0.0166088 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0152365 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0136027 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0135525 |
| MED13L | mediator complex subunit 13-like | -0.0130774 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0115482 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0114425 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0107553 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00977837 |
| MED13 | mediator complex subunit 13 | -0.00829304 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00821266 |
| CD44 | CD44 molecule (Indian blood group) | -0.00799988 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00783145 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00712709 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0042778 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00341222 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00329204 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.00280417 |
| CDH13 | cadherin 13 | -0.00255566 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.00190915 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.00164871 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -3.1102E-4 |
