| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rapamycin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0717914 |
| TXNRD1 | thioredoxin reductase 1 | 0.0589788 |
| TJP1 | tight junction protein 1 | 0.0439785 |
| EZR | ezrin | 0.040215 |
| FLNB | filamin B, beta | 0.0373245 |
| ZNF608 | zinc finger protein 608 | 0.0356882 |
| ECT2 | epithelial cell transforming 2 | 0.0354028 |
| EGFR | epidermal growth factor receptor | 0.0313248 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0311083 |
| GOLGA4 | golgin A4 | 0.0301837 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0295422 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0294979 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0286505 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0280231 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0272257 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270446 |
| CCNL1 | cyclin L1 | 0.0266872 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0258774 |
| PDGFC | platelet derived growth factor C | 0.0254742 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0249284 |
| ANK2 | ankyrin 2, neuronal | 0.023928 |
| RTN4 | reticulon 4 | 0.0234015 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0230015 |
| NUP58 | nucleoporin 58 | 0.0227752 |
| TMEM65 | transmembrane protein 65 | 0.0222356 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0221257 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0218616 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0217134 |
| NCKAP1 | NCK-associated protein 1 | 0.0217096 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0216005 |
| RNF145 | ring finger protein 145 | 0.0209368 |
| METTL15 | methyltransferase like 15 | 0.020535 |
| ZNF292 | zinc finger protein 292 | 0.02051 |
| PRELID2 | PRELI domain containing 2 | 0.0204401 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0204136 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0201662 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0194868 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0193259 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0187404 |
| GLI2 | GLI family zinc finger 2 | 0.0185367 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.018403 |
| NBAS | neuroblastoma amplified sequence | 0.018152 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0181109 |
| BMP2K | BMP2 inducible kinase | 0.0180634 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.017653 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0175814 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0175526 |
| HDAC9 | histone deacetylase 9 | 0.0174747 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0172823 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0172758 |
| CDC73 | cell division cycle 73 | 0.0170889 |
| PLK2 | polo-like kinase 2 | 0.0170289 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0168468 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0168225 |
| SMYD3 | SET and MYND domain containing 3 | 0.0167364 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0166515 |
| ARRDC3 | arrestin domain containing 3 | 0.0159952 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0159501 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0159234 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0158048 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0157551 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0154285 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0153809 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0153232 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0151891 |
| ITGA6 | integrin, alpha 6 | 0.0149111 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0147503 |
| PCGF5 | polycomb group ring finger 5 | 0.0147047 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0146004 |
| ZNF638 | zinc finger protein 638 | 0.0145466 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0144044 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0143778 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0143596 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0141496 |
| PCBP2 | poly(rC) binding protein 2 | 0.0140967 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0139803 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0137966 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0137569 |
| USP34 | ubiquitin specific peptidase 34 | 0.0137516 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0137361 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0136214 |
| LDHA | lactate dehydrogenase A | 0.0136013 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0134186 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0134168 |
| COG6 | component of oligomeric golgi complex 6 | 0.0133544 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0133139 |
| USP24 | ubiquitin specific peptidase 24 | 0.0131258 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0131149 |
| CCDC68 | coiled-coil domain containing 68 | 0.0129442 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0128897 |
| PAQR3 | progestin and adipoQ receptor family member III | 0.0128668 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0125033 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0123929 |
| TXNIP | thioredoxin interacting protein | 0.0123801 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0123328 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0122959 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0122786 |
| QKI | QKI, KH domain containing, RNA binding | 0.0121133 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0120944 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0118148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.336715 |
| RPS6 | ribosomal protein S6 | -0.0994004 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0944809 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0928528 |
| BMP10 | bone morphogenetic protein 10 | -0.0756769 |
| RPL35A | ribosomal protein L35a | -0.0751165 |
| RPS8 | ribosomal protein S8 | -0.0734326 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0729881 |
| RPL31 | ribosomal protein L31 | -0.0672091 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0670087 |
| RPL34 | ribosomal protein L34 | -0.0619235 |
| FOXP1 | forkhead box P1 | -0.0537351 |
| RPLP1 | ribosomal protein, large, P1 | -0.0536313 |
| RPS13 | ribosomal protein S13 | -0.051423 |
| RPS25 | ribosomal protein S25 | -0.0460514 |
| RPL19 | ribosomal protein L19 | -0.0458429 |
| RPS27A | ribosomal protein S27a | -0.0444511 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0440041 |
| RPS23 | ribosomal protein S23 | -0.0422489 |
| RPS3 | ribosomal protein S3 | -0.0421751 |
| RPL26 | ribosomal protein L26 | -0.0420303 |
| RPL37A | ribosomal protein L37a | -0.0420232 |
| RPL9 | ribosomal protein L9 | -0.0402387 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0392348 |
| RPLP2 | ribosomal protein, large, P2 | -0.0374185 |
| RPS29 | ribosomal protein S29 | -0.0344889 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0344402 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0339172 |
| RPL30 | ribosomal protein L30 | -0.0326106 |
| RPS24 | ribosomal protein S24 | -0.0325356 |
| AHNAK | AHNAK nucleoprotein | -0.0324632 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0319639 |
| RPL23 | ribosomal protein L23 | -0.0316988 |
| RPL38 | ribosomal protein L38 | -0.0309567 |
| RPS27 | ribosomal protein S27 | -0.0308439 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307392 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0305284 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0303742 |
| S100A9 | S100 calcium binding protein A9 | -0.0296551 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0294767 |
| RPS19 | ribosomal protein S19 | -0.0291892 |
| RPL8 | ribosomal protein L8 | -0.0286068 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0280831 |
| VCL | vinculin | -0.0277788 |
| RPL37 | ribosomal protein L37 | -0.0277697 |
| MKI67 | marker of proliferation Ki-67 | -0.0274982 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0268967 |
| RPL7A | ribosomal protein L7a | -0.0264372 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0261211 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0258893 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.025682 |
| SEPTIN9 | septin 9 | -0.0253129 |
| NOP56 | NOP56 ribonucleoprotein | -0.0251227 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0250668 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0246695 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0245868 |
| RPS21 | ribosomal protein S21 | -0.0244292 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0243922 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0242917 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0241398 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.023739 |
| ASPH | aspartate beta-hydroxylase | -0.0237097 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0233377 |
| RPL10A | ribosomal protein L10a | -0.0232909 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0232441 |
| RPL36A | ribosomal protein L36a | -0.0221264 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0220494 |
| HLA-B | major histocompatibility complex, class I, B | -0.021665 |
| NEBL | nebulette | -0.0216558 |
| RACK1 | receptor for activated C kinase 1 | -0.0216098 |
| RPL36 | ribosomal protein L36 | -0.0212229 |
| RPL13A | ribosomal protein L13a | -0.0211721 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0208977 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0208501 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0208032 |
| FTL | ferritin, light polypeptide | -0.0205346 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0205018 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0204346 |
| RPL15 | ribosomal protein L15 | -0.0203712 |
| RPS16 | ribosomal protein S16 | -0.0203463 |
| RPL35 | ribosomal protein L35 | -0.0201942 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0201888 |
| HMGB1 | high mobility group box 1 | -0.0198665 |
| RPS28 | ribosomal protein S28 | -0.0198591 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0198259 |
| RPS12 | ribosomal protein S12 | -0.0194282 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0193132 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0190221 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0189945 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0189579 |
| MYOF | myoferlin | -0.01891 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0188193 |
| RPL27A | ribosomal protein L27a | -0.0188082 |
| CCND1 | cyclin D1 | -0.0187942 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0185626 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0185373 |
| TUBA1B | tubulin, alpha 1b | -0.0185122 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0184901 |
| ITGA10 | integrin, alpha 10 | -0.018405 |
| S100A10 | S100 calcium binding protein A10 | -0.0183991 |