| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rapamycin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.16877 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.105251 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0964871 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.089575 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0813769 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0778192 |
| DST | dystonin | 0.0722754 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0712264 |
| VCAN | versican | 0.0678665 |
| VEGFA | vascular endothelial growth factor A | 0.0657908 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.061218 |
| RND3 | Rho family GTPase 3 | 0.056183 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0530488 |
| RAI14 | retinoic acid induced 14 | 0.0515688 |
| PGK1 | phosphoglycerate kinase 1 | 0.0512031 |
| CDH13 | cadherin 13 | 0.0511344 |
| HLA-E | major histocompatibility complex, class I, E | 0.0501285 |
| PDE10A | phosphodiesterase 10A | 0.049813 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0489707 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0476613 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.047438 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0467311 |
| TMSB4X | thymosin beta 4, X-linked | 0.0458685 |
| PHF3 | PHD finger protein 3 | 0.0448715 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0442007 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0419373 |
| ADM | adrenomedullin | 0.040584 |
| MMP12 | matrix metallopeptidase 12 | 0.0405193 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0401516 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0396782 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0395657 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0395 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0388439 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0384941 |
| CTSB | cathepsin B | 0.0384536 |
| GLIS3 | GLIS family zinc finger 3 | 0.0378909 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.036191 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0355202 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0351763 |
| FN1 | fibronectin 1 | 0.0340384 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0333511 |
| CANX | calnexin | 0.0332802 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0329796 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322866 |
| MXI1 | MAX interactor 1, dimerization protein | 0.032261 |
| APP | amyloid beta (A4) precursor protein | 0.0317645 |
| ZNF292 | zinc finger protein 292 | 0.0314887 |
| TNS3 | tensin 3 | 0.030934 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0305127 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0303448 |
| EGFR | epidermal growth factor receptor | 0.0299671 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0299014 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0298829 |
| MYOF | myoferlin | 0.0297921 |
| CADM1 | cell adhesion molecule 1 | 0.0297642 |
| CALR | calreticulin | 0.0297629 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0297408 |
| STC2 | stanniocalcin 2 | 0.0296876 |
| FMNL2 | formin-like 2 | 0.0295132 |
| IER3 | immediate early response 3 | 0.0289811 |
| TMEM132D | transmembrane protein 132D | 0.0287045 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0284499 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0281761 |
| PHF21A | PHD finger protein 21A | 0.0278685 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276477 |
| DIAPH2 | diaphanous-related formin 2 | 0.0276425 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0273137 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0272285 |
| OGA | O-GlcNAcase | 0.0271959 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0271208 |
| OPTN | optineurin | 0.026693 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0261499 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0259847 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0257712 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0257072 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0253577 |
| ATP13A3 | ATPase type 13A3 | 0.0253433 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0251083 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0249178 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.024584 |
| COL5A1 | collagen, type V, alpha 1 | 0.024474 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0242128 |
| AHNAK | AHNAK nucleoprotein | 0.024037 |
| INHBA | inhibin, beta A | 0.0237728 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0237694 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0236607 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0228672 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0227138 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0226017 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0225557 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224898 |
| CEP250 | centrosomal protein 250kDa | 0.0222527 |
| YEATS2 | YEATS domain containing 2 | 0.022137 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0220043 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0216545 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0215064 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0213835 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0212352 |
| BNC2 | basonuclin 2 | 0.0209029 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0207762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232482 |
| TMSB10 | thymosin beta 10 | -0.114569 |
| FTL | ferritin, light polypeptide | -0.102374 |
| HLA-B | major histocompatibility complex, class I, B | -0.0937495 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0888881 |
| MT2A | metallothionein 2A | -0.0820371 |
| RPS6 | ribosomal protein S6 | -0.0766573 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.075227 |
| RPS19 | ribosomal protein S19 | -0.0640979 |
| B2M | beta-2-microglobulin | -0.0617884 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0609632 |
| RPL35A | ribosomal protein L35a | -0.052232 |
| RPS23 | ribosomal protein S23 | -0.0515357 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0502552 |
| RPLP1 | ribosomal protein, large, P1 | -0.0472025 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0441398 |
| RPS4X | ribosomal protein S4, X-linked | -0.0415587 |
| RPLP2 | ribosomal protein, large, P2 | -0.0385611 |
| RPL19 | ribosomal protein L19 | -0.037038 |
| RPS21 | ribosomal protein S21 | -0.0369679 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0369484 |
| RPL11 | ribosomal protein L11 | -0.0348649 |
| VCL | vinculin | -0.0337512 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.032588 |
| RPL23 | ribosomal protein L23 | -0.0322693 |
| RPL9 | ribosomal protein L9 | -0.0317715 |
| ACTG1 | actin gamma 1 | -0.0314583 |
| RPS13 | ribosomal protein S13 | -0.0312584 |
| RPL36 | ribosomal protein L36 | -0.0310861 |
| RPL32 | ribosomal protein L32 | -0.0307078 |
| RPL35 | ribosomal protein L35 | -0.0303107 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0300681 |
| RPL12 | ribosomal protein L12 | -0.0294246 |
| RPS12 | ribosomal protein S12 | -0.0282327 |
| RPL7A | ribosomal protein L7a | -0.0277937 |
| TXNIP | thioredoxin interacting protein | -0.0277657 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0277345 |
| RPL28 | ribosomal protein L28 | -0.0276312 |
| FRMD4A | FERM domain containing 4A | -0.0275722 |
| POTEF | POTE ankyrin domain family, member F | -0.0268414 |
| MKI67 | marker of proliferation Ki-67 | -0.0255951 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0255772 |
| RPS8 | ribosomal protein S8 | -0.0255015 |
| RPLP0 | ribosomal protein, large, P0 | -0.0254207 |
| S100A9 | S100 calcium binding protein A9 | -0.0253029 |
| RPL5 | ribosomal protein L5 | -0.0252349 |
| RPS10 | ribosomal protein S10 | -0.0251663 |
| RPL7 | ribosomal protein L7 | -0.0247705 |
| RPL37A | ribosomal protein L37a | -0.0247515 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0246221 |
| RPS27 | ribosomal protein S27 | -0.024406 |
| PFN1 | profilin 1 | -0.0241689 |
| RPS14 | ribosomal protein S14 | -0.0237573 |
| RPS29 | ribosomal protein S29 | -0.0235794 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0234439 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0234221 |
| EGR1 | early growth response 1 | -0.0228937 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.022851 |
| RPL8 | ribosomal protein L8 | -0.0226137 |
| DUSP5 | dual specificity phosphatase 5 | -0.0222356 |
| TXNRD1 | thioredoxin reductase 1 | -0.0220767 |
| CCNL1 | cyclin L1 | -0.0219457 |
| RPS15 | ribosomal protein S15 | -0.0218105 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0214944 |
| CST3 | cystatin C | -0.0214745 |
| RPL36A | ribosomal protein L36a | -0.0214189 |
| CENPF | centromere protein F, 350/400kDa | -0.0212894 |
| KLF6 | Kruppel-like factor 6 | -0.0204837 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0204235 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0203659 |
| FOSL1 | FOS-like antigen 1 | -0.0200859 |
| RPL31 | ribosomal protein L31 | -0.0197206 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0195685 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0195403 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0189366 |
| RPS25 | ribosomal protein S25 | -0.0188602 |
| RPS11 | ribosomal protein S11 | -0.0187576 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0186301 |
| RPS20 | ribosomal protein S20 | -0.0185868 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0183084 |
| CD44 | CD44 molecule (Indian blood group) | -0.0182727 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0181012 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0180495 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0180226 |
| HMGA1 | high mobility group AT-hook 1 | -0.0179881 |
| UBB | ubiquitin B | -0.0179428 |
| RPL10A | ribosomal protein L10a | -0.0178204 |
| NKTR | natural killer cell triggering receptor | -0.0177807 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0177002 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0175522 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0173961 |
| RPL30 | ribosomal protein L30 | -0.0173886 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.01721 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0168771 |
| PKM | pyruvate kinase, muscle | -0.0165083 |
| DEK | DEK proto-oncogene | -0.0163647 |
| RACK1 | receptor for activated C kinase 1 | -0.0162286 |
| PTMA | prothymosin, alpha | -0.0162006 |
| HMGB1 | high mobility group box 1 | -0.0161426 |
| TAPBP | TAP binding protein (tapasin) | -0.016028 |
