| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.136535 |
| COL6A3 | collagen, type VI, alpha 3 | 0.122966 |
| CDH13 | cadherin 13 | 0.103054 |
| NRXN3 | neurexin 3 | 0.0762008 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0749367 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.071979 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0691706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0688048 |
| IL6 | interleukin 6 | 0.0559793 |
| EGFR | epidermal growth factor receptor | 0.0548996 |
| RND3 | Rho family GTPase 3 | 0.0546228 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0529614 |
| FNIP1 | folliculin interacting protein 1 | 0.0506555 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0505323 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.049953 |
| RAI14 | retinoic acid induced 14 | 0.0494872 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0490612 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0485214 |
| VEGFA | vascular endothelial growth factor A | 0.0478642 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0471096 |
| SEPTIN9 | septin 9 | 0.0467305 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0465788 |
| COL5A1 | collagen, type V, alpha 1 | 0.0456289 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0451027 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0429668 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0422414 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0417868 |
| MMP12 | matrix metallopeptidase 12 | 0.0406883 |
| HDAC9 | histone deacetylase 9 | 0.0399606 |
| VEGFC | vascular endothelial growth factor C | 0.03958 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.039366 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0392738 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0389565 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0377475 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0364896 |
| EFNA5 | ephrin-A5 | 0.0358489 |
| LOX | lysyl oxidase | 0.0358427 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0357489 |
| EXOC4 | exocyst complex component 4 | 0.0355576 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0354408 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.033478 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0328404 |
| ZNF638 | zinc finger protein 638 | 0.0327549 |
| NDRG1 | N-myc downstream regulated 1 | 0.0324471 |
| AUTS2 | autism susceptibility candidate 2 | 0.0321467 |
| CDK13 | cyclin-dependent kinase 13 | 0.0320216 |
| KAZN | kazrin, periplakin interacting protein | 0.0319164 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0319031 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0315074 |
| USP34 | ubiquitin specific peptidase 34 | 0.0312719 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0312143 |
| MYO9A | myosin IXA | 0.0301742 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0299791 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0293553 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0291733 |
| SEPTIN2 | septin 2 | 0.0288577 |
| SQSTM1 | sequestosome 1 | 0.0276756 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.027462 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0272949 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0272944 |
| KYNU | kynureninase | 0.0270297 |
| ANXA5 | annexin A5 | 0.0269775 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0267551 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0265735 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0264843 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0264467 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0263476 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0263285 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0258287 |
| PLEC | plectin | 0.0256175 |
| COPA | coatomer protein complex, subunit alpha | 0.0252353 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0250697 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0248898 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0248251 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0246972 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0246141 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0243165 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0241553 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0241336 |
| HELZ | helicase with zinc finger | 0.0241125 |
| TNS3 | tensin 3 | 0.0240684 |
| GOLGB1 | golgin B1 | 0.0239911 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0238656 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0238077 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0237341 |
| FAM13A | family with sequence similarity 13, member A | 0.0237066 |
| AHNAK | AHNAK nucleoprotein | 0.0236787 |
| UBC | ubiquitin C | 0.0235506 |
| DIDO1 | death inducer-obliterator 1 | 0.0234824 |
| PYGL | phosphorylase, glycogen, liver | 0.0234813 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0232414 |
| LOXL2 | lysyl oxidase-like 2 | 0.0229768 |
| PGK1 | phosphoglycerate kinase 1 | 0.0228894 |
| C1D | C1D nuclear receptor corepressor | 0.0227259 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0225046 |
| ANTXR2 | anthrax toxin receptor 2 | 0.022244 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0221392 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0221087 |
| NOTCH2 | notch 2 | 0.0219903 |
| ACTN1 | actinin, alpha 1 | 0.0217104 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.264662 |
| MT2A | metallothionein 2A | -0.154164 |
| TMSB10 | thymosin beta 10 | -0.120473 |
| PTMA | prothymosin, alpha | -0.0863171 |
| B2M | beta-2-microglobulin | -0.0715245 |
| H3-3B | H3.3 histone B | -0.0666228 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0637365 |
| VIM | vimentin | -0.059624 |
| HLA-B | major histocompatibility complex, class I, B | -0.0548132 |
| RPL11 | ribosomal protein L11 | -0.0509756 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0476095 |
| MT1X | metallothionein 1X | -0.043714 |
| ANLN | anillin, actin binding protein | -0.0428176 |
| MEF2A | myocyte enhancer factor 2A | -0.0412932 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0400142 |
| RPLP1 | ribosomal protein, large, P1 | -0.0384873 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0384046 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0382074 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.037833 |
| PTN | pleiotrophin | -0.0377501 |
| RPL26 | ribosomal protein L26 | -0.036843 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366144 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0362155 |
| RPL37 | ribosomal protein L37 | -0.0360729 |
| CCNI | cyclin I | -0.03548 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0351961 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0331873 |
| PKM | pyruvate kinase, muscle | -0.0324431 |
| RPS8 | ribosomal protein S8 | -0.0316332 |
| RPS24 | ribosomal protein S24 | -0.0314683 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0307011 |
| RPS6 | ribosomal protein S6 | -0.0299579 |
| RPL32 | ribosomal protein L32 | -0.0295781 |
| S100A6 | S100 calcium binding protein A6 | -0.0292081 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.028173 |
| RPS2 | ribosomal protein S2 | -0.0281571 |
| ZNF395 | zinc finger protein 395 | -0.0281134 |
| COL1A1 | collagen, type I, alpha 1 | -0.0279895 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0277658 |
| RPL35A | ribosomal protein L35a | -0.0276396 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0276217 |
| RPL23 | ribosomal protein L23 | -0.0275399 |
| ZNF292 | zinc finger protein 292 | -0.0271822 |
| RPS23 | ribosomal protein S23 | -0.0271472 |
| HMGB2 | high mobility group box 2 | -0.027087 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0266887 |
| GNAS | GNAS complex locus | -0.0265885 |
| EGR1 | early growth response 1 | -0.0264325 |
| RPS5 | ribosomal protein S5 | -0.0263687 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0261175 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0261118 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0257842 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0256005 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0254597 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0249602 |
| HMGB1 | high mobility group box 1 | -0.0247901 |
| RPL34 | ribosomal protein L34 | -0.0247747 |
| TFG | TRK-fused gene | -0.0246659 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0244759 |
| MTPN | myotrophin | -0.0239633 |
| TNPO1 | transportin 1 | -0.0238215 |
| RPL18 | ribosomal protein L18 | -0.0234618 |
| PFN1 | profilin 1 | -0.0232741 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0231527 |
| RPL7 | ribosomal protein L7 | -0.0228654 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0228418 |
| WDR45B | WD repeat domain 45B | -0.0224525 |
| SETD5 | SET domain containing 5 | -0.0224258 |
| TMEM59 | transmembrane protein 59 | -0.0222631 |
| RPLP0 | ribosomal protein, large, P0 | -0.0222177 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221251 |
| MKI67 | marker of proliferation Ki-67 | -0.0219378 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0215192 |
| RPS13 | ribosomal protein S13 | -0.0213698 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0213499 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0212797 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.02119 |
| RPL37A | ribosomal protein L37a | -0.0211279 |
| PDE10A | phosphodiesterase 10A | -0.02103 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0209377 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0206613 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0205872 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0204388 |
| MED13 | mediator complex subunit 13 | -0.0203381 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0203229 |
| JMJD1C | jumonji domain containing 1C | -0.0201518 |
| S100A9 | S100 calcium binding protein A9 | -0.0201216 |
| RPL12 | ribosomal protein L12 | -0.020013 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0197547 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0197455 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0196248 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.019505 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0193986 |
| RPS15 | ribosomal protein S15 | -0.019364 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0193523 |
| RPL31 | ribosomal protein L31 | -0.0192938 |
| RACK1 | receptor for activated C kinase 1 | -0.019073 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0190208 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0190142 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0190139 |
