| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rapamycin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rapamycin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0972827 |
| SMAD3 | SMAD family member 3 | 0.0773864 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0630599 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0618768 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.054774 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0540712 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0526762 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0525709 |
| TXNRD1 | thioredoxin reductase 1 | 0.051229 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0487255 |
| CAPRIN2 | caprin family member 2 | 0.0456681 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0433893 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.042697 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0414349 |
| FLNA | filamin A, alpha | 0.0413681 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0412968 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0398261 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0397498 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0396357 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0388005 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0382303 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0377165 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0368333 |
| RBM39 | RNA binding motif protein 39 | 0.0365036 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0363528 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0363061 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0355977 |
| CLTC | clathrin, heavy chain (Hc) | 0.0345595 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0340907 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0330307 |
| MKI67 | marker of proliferation Ki-67 | 0.0320464 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0313477 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0309599 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0302973 |
| KIF5B | kinesin family member 5B | 0.0294752 |
| VCL | vinculin | 0.0292771 |
| TUT7 | terminal uridylyl transferase 7 | 0.0291064 |
| TPX2 | TPX2, microtubule-associated | 0.0290026 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0289802 |
| LDLR | low density lipoprotein receptor | 0.0289732 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0289352 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.028637 |
| LDHA | lactate dehydrogenase A | 0.0286283 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0283383 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282887 |
| RPS3 | ribosomal protein S3 | 0.0279857 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0271913 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0271593 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0265889 |
| RAB10 | RAB10, member RAS oncogene family | 0.0263321 |
| CENPE | centromere protein E, 312kDa | 0.0258654 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0258573 |
| UBQLN1 | ubiquilin 1 | 0.0258284 |
| RPL23 | ribosomal protein L23 | 0.0257792 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0250601 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.024858 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0239588 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0238802 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0238456 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0236982 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0232916 |
| PLEC | plectin | 0.0224905 |
| CENPF | centromere protein F, 350/400kDa | 0.0224805 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.022308 |
| SET | SET nuclear proto-oncogene | 0.0221544 |
| IDS | iduronate 2-sulfatase | 0.0221043 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0216839 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0215894 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0215575 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0209714 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0206326 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0204443 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0203821 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0203101 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0201197 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0201002 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.019774 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0197217 |
| DNER | delta/notch-like EGF repeat containing | 0.0197087 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0196464 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.0196461 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0195895 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0195106 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0193342 |
| SAFB | scaffold attachment factor B | 0.0191288 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.019027 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0190105 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0188988 |
| CEP83 | centrosomal protein 83kDa | 0.0188953 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0188551 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0188085 |
| NAV2 | neuron navigator 2 | 0.0187731 |
| PSPC1 | paraspeckle component 1 | 0.0186985 |
| PRKCA | protein kinase C, alpha | 0.0186677 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0185662 |
| TUBB | tubulin, beta class I | 0.0185621 |
| HJURP | Holliday junction recognition protein | 0.0185611 |
| INTS6 | integrator complex subunit 6 | 0.0185349 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0183413 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0183288 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.226019 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0847512 |
| VIM | vimentin | -0.0826872 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0806932 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.080142 |
| IGF2 | insulin-like growth factor 2 | -0.0779598 |
| TMSB10 | thymosin beta 10 | -0.0765688 |
| PTMA | prothymosin, alpha | -0.0730283 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0621274 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0606973 |
| DST | dystonin | -0.0562386 |
| RAD51B | RAD51 paralog B | -0.0558628 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.053584 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0530083 |
| MT2A | metallothionein 2A | -0.0524011 |
| ZNF609 | zinc finger protein 609 | -0.0520505 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0507338 |
| PKM | pyruvate kinase, muscle | -0.0502159 |
| CD44 | CD44 molecule (Indian blood group) | -0.048987 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0447018 |
| ZNF638 | zinc finger protein 638 | -0.0446616 |
| RIGI | RNA sensor RIG-I | -0.0434624 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0431974 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0431855 |
| DSE | dermatan sulfate epimerase | -0.0415533 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0415247 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0410072 |
| FAM3C | family with sequence similarity 3, member C | -0.0403949 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0389916 |
| GPC5 | glypican 5 | -0.0389446 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0388037 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0381315 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0371665 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0365578 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0364959 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.036224 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.034583 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0339848 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0337287 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0334693 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0333215 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0329928 |
| STXBP1 | syntaxin binding protein 1 | -0.0329658 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0327962 |
| PHF20 | PHD finger protein 20 | -0.0327654 |
| TXNIP | thioredoxin interacting protein | -0.0324363 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0322437 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0320648 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0316474 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0312048 |
| EGR1 | early growth response 1 | -0.0307242 |
| S100A9 | S100 calcium binding protein A9 | -0.0302342 |
| FTL | ferritin, light polypeptide | -0.0301307 |
| ATM | ATM serine/threonine kinase | -0.030068 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0291102 |
| HLA-A | major histocompatibility complex, class I, A | -0.0290959 |
| HLA-B | major histocompatibility complex, class I, B | -0.0290252 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0289365 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0289079 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.02841 |
| TAOK3 | TAO kinase 3 | -0.0282826 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0282165 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0280305 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0279367 |
| RPL35A | ribosomal protein L35a | -0.0278139 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0277935 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0275848 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0273486 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0273278 |
| B2M | beta-2-microglobulin | -0.0272399 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271011 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0269893 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0268553 |
| IER3 | immediate early response 3 | -0.0267808 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | -0.0267205 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0266485 |
| SSH1 | slingshot protein phosphatase 1 | -0.0264117 |
| VMP1 | vacuole membrane protein 1 | -0.0262421 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0262239 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0261064 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.02587 |
| ENO1 | enolase 1, (alpha) | -0.0258554 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.025534 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.025485 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0253405 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0253077 |
| HMGA2 | high mobility group AT-hook 2 | -0.025161 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0248713 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0244189 |
| MYOF | myoferlin | -0.0242993 |
| GOLGB1 | golgin B1 | -0.0241084 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.024074 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0238903 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0237573 |
| H3-3B | H3.3 histone B | -0.0234931 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0234618 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0232741 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0232178 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0231011 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0230174 |
