Ras protein signal transduction Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state. (Gene Ontology, GO_0007265)
External Link http://amigo.geneontology.org/amigo/term/GO_0007265
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Genes

145 genes participating in the Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABI2 abl-interactor 2
ADGRG1 adhesion G protein-coupled receptor G1
ADRA2A adrenoceptor alpha 2A
AGTR1 angiotensin II receptor, type 1
AIF1 allograft inflammatory factor 1
ARHGAP1 Rho GTPase activating protein 1
ARHGAP29 Rho GTPase activating protein 29
ARHGAP35 Rho GTPase activating protein 35
ARHGAP4 Rho GTPase activating protein 4
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
BRAP BRCA1 associated protein
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
CCNA2 cyclin A2
CDH13 cadherin 13
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CFL1 cofilin 1 (non-muscle)
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL1A2 collagen, type I, alpha 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CYFIP1 cytoplasmic FMR1 interacting protein 1
DBNL drebrin-like
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
DOK4 docking protein 4
DOK5 docking protein 5
DOK6 docking protein 6
ELMO1 engulfment and cell motility 1
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
EPS8L3 EPS8-like 3
ERAS ES cell expressed Ras
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF2 fibroblast growth factor 2 (basic)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GDI1 GDP dissociation inhibitor 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPSM2 G-protein signaling modulator 2
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HACD3 3-hydroxyacyl-CoA dehydratase 3
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HRAS Harvey rat sarcoma viral oncogene homolog
IGF1 insulin-like growth factor 1 (somatomedin C)
KIAA0355 KIAA0355
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KSR1 kinase suppressor of ras 1
LIMK1 LIM domain kinase 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MRAS muscle RAS oncogene homolog
MYO9B myosin IXB
NCKAP1 NCK-associated protein 1
NF1 neurofibromin 1
NGFR nerve growth factor receptor
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTN1 netrin 1
ORC3 origin recognition complex, subunit 3
PARK7 parkinson protein 7
PDPN podoplanin
PHACTR4 phosphatase and actin regulator 4
PLCE1 phospholipase C, epsilon 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
PLK2 polo-like kinase 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RACGAP1 Rac GTPase activating protein 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP1BL RAP1B, member of RAS oncogene family pseudogene
RAP2A RAP2A, member of RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RAP2C RAP2C, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASGEF1A RasGEF domain family, member 1A
RASGEF1B RasGEF domain family, member 1B
RASGEF1C RasGEF domain family, member 1C
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASGRP4 RAS guanyl releasing protein 4
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RGL4 ral guanine nucleotide dissociation stimulator-like 4
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOD ras homolog family member D
RHOG ras homolog family member G
RIPOR1 RHO family interacting cell polarization regulator 1
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROPN1B rhophilin associated tail protein 1B
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RTKN rhotekin
SGSM3 small G protein signaling modulator 3
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SHTN1 shootin 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53 tumor protein p53
USP50 ubiquitin specific peptidase 50
USP8 ubiquitin specific peptidase 8
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1