| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Regorafenib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Regorafenib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.241819 |
| LSAMP | limbic system-associated membrane protein | 0.109448 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.074633 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.06942 |
| MSI2 | musashi RNA-binding protein 2 | 0.0628975 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0579891 |
| NDRG1 | N-myc downstream regulated 1 | 0.0577034 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0530282 |
| ANTXR1 | anthrax toxin receptor 1 | 0.047222 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0417269 |
| VEGFA | vascular endothelial growth factor A | 0.0391321 |
| RAD51B | RAD51 paralog B | 0.0388887 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0372847 |
| EGR1 | early growth response 1 | 0.0356483 |
| YEATS2 | YEATS domain containing 2 | 0.0351785 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0347078 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0330869 |
| TRIM24 | tripartite motif containing 24 | 0.0307393 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0306988 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0302087 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.030001 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0295984 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0295436 |
| KLF6 | Kruppel-like factor 6 | 0.0295237 |
| FAM13A | family with sequence similarity 13, member A | 0.0287852 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0284633 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0277279 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0266021 |
| FRMD5 | FERM domain containing 5 | 0.0265272 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0264945 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264199 |
| GPC6 | glypican 6 | 0.0261739 |
| CDON | cell adhesion associated, oncogene regulated | 0.0260939 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0260904 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0258273 |
| PDE8A | phosphodiesterase 8A | 0.0255543 |
| EFNA5 | ephrin-A5 | 0.0248662 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0247622 |
| VCL | vinculin | 0.0244373 |
| MX2 | MX dynamin-like GTPase 2 | 0.0240055 |
| SMAD6 | SMAD family member 6 | 0.023787 |
| RGS4 | regulator of G-protein signaling 4 | 0.0234935 |
| CERK | ceramide kinase | 0.0231725 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0231429 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0231015 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0227672 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0223913 |
| TTYH3 | tweety family member 3 | 0.0222581 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0215896 |
| RNF144A | ring finger protein 144A | 0.0215779 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0215012 |
| L1CAM | L1 cell adhesion molecule | 0.0209875 |
| MTREX | Mtr4 exosome RNA helicase | 0.0208858 |
| EVI5 | ecotropic viral integration site 5 | 0.0207606 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0206342 |
| CBX5 | chromobox homolog 5 | 0.0206186 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0206155 |
| DACH2 | dachshund family transcription factor 2 | 0.0204561 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0201699 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0199202 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.019909 |
| GLI2 | GLI family zinc finger 2 | 0.0197443 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0197346 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0195713 |
| BBX | bobby sox homolog (Drosophila) | 0.0195582 |
| LDHA | lactate dehydrogenase A | 0.0195192 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0192138 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0191977 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0190559 |
| KIF26B | kinesin family member 26B | 0.0190552 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0190049 |
| CASC3 | cancer susceptibility candidate 3 | 0.0188642 |
| PTEN | phosphatase and tensin homolog | 0.0187763 |
| EP400 | E1A binding protein p400 | 0.0186985 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0186861 |
| COPA | coatomer protein complex, subunit alpha | 0.0186379 |
| RET | ret proto-oncogene | 0.0185924 |
| FAT1 | FAT atypical cadherin 1 | 0.0184675 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0184486 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0183976 |
| USP34 | ubiquitin specific peptidase 34 | 0.0182657 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0182114 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0177751 |
| H1-0 | H1.0 linker histone | 0.0177703 |
| KCTD20 | potassium channel tetramerization domain containing 20 | 0.0176728 |
| RPL4 | ribosomal protein L4 | 0.0174959 |
| ASPH | aspartate beta-hydroxylase | 0.0173386 |
| MCL1 | myeloid cell leukemia 1 | 0.0173331 |
| GPR173 | G protein-coupled receptor 173 | 0.0172071 |
| RARA | retinoic acid receptor, alpha | 0.0170096 |
| NREP | neuronal regeneration related protein | 0.016996 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0168247 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0167807 |
| TRIB2 | tribbles pseudokinase 2 | 0.0167036 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0166821 |
| SETBP1 | SET binding protein 1 | 0.016667 |
| N4BP1 | NEDD4 binding protein 1 | 0.0166522 |
| PATJ | PATJ crumbs cell polarity complex component | 0.016575 |
| NGLY1 | N-glycanase 1 | 0.0165307 |
| TENM4 | teneurin transmembrane protein 4 | 0.0162666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122914 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0808902 |
| TLE4 | transducin-like enhancer of split 4 | -0.0793032 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0731448 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0704996 |
| PCBP2 | poly(rC) binding protein 2 | -0.0695266 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0651729 |
| CLTC | clathrin, heavy chain (Hc) | -0.0644241 |
| SYT1 | synaptotagmin I | -0.0605678 |
| HMGB2 | high mobility group box 2 | -0.0600081 |
| PCDH9 | protocadherin 9 | -0.059154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0579747 |
| BPTF | bromodomain PHD finger transcription factor | -0.0578099 |
| ENAH | enabled homolog (Drosophila) | -0.0542523 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0533349 |
| RPS6 | ribosomal protein S6 | -0.0526052 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0520366 |
| RPS24 | ribosomal protein S24 | -0.0517021 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0505082 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.048272 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0481981 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0472063 |
| GLG1 | golgi glycoprotein 1 | -0.0468755 |
| RPLP1 | ribosomal protein, large, P1 | -0.0465369 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0465336 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0463757 |
| RPL35A | ribosomal protein L35a | -0.0462777 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0455825 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0455246 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0453874 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0449658 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0449493 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0449136 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0447077 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0437363 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0434369 |
| RPL38 | ribosomal protein L38 | -0.0431852 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0431265 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0428698 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0425288 |
| RPL12 | ribosomal protein L12 | -0.0424645 |
| MAP1B | microtubule-associated protein 1B | -0.0417586 |
| RPS12 | ribosomal protein S12 | -0.0414175 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0413954 |
| PARD3 | par-3 family cell polarity regulator | -0.0412064 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0405466 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0401091 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0394968 |
| RPS2 | ribosomal protein S2 | -0.0392653 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0390439 |
| PTMA | prothymosin, alpha | -0.0388918 |
| RPLP0 | ribosomal protein, large, P0 | -0.0385506 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0373031 |
| MBTD1 | mbt domain containing 1 | -0.0371831 |
| ACTG1 | actin gamma 1 | -0.0369328 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365775 |
| S100A6 | S100 calcium binding protein A6 | -0.0365149 |
| AHNAK | AHNAK nucleoprotein | -0.0364748 |
| VIM | vimentin | -0.0362558 |
| ERBIN | erbb2 interacting protein | -0.0361278 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0360496 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0357271 |
| FMN1 | formin 1 | -0.0354476 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0348744 |
| PHF3 | PHD finger protein 3 | -0.0347034 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0346665 |
| PAPOLA | poly(A) polymerase alpha | -0.0346195 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0345695 |
| RPL19 | ribosomal protein L19 | -0.0345243 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0344503 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.034355 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0342723 |
| TLK2 | tousled-like kinase 2 | -0.0342162 |
| APP | amyloid beta (A4) precursor protein | -0.033548 |
| CCDC47 | coiled-coil domain containing 47 | -0.033416 |
| RPL11 | ribosomal protein L11 | -0.033302 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.033256 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0332049 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0329078 |
| RPS3 | ribosomal protein S3 | -0.0326735 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0326027 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0323495 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0323106 |
| B2M | beta-2-microglobulin | -0.0322442 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0320196 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0316847 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0315935 |
| H3-3B | H3.3 histone B | -0.0315883 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0315076 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0314389 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0313483 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0312692 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0312244 |
| HSPA8 | heat shock 70kDa protein 8 | -0.031213 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0311592 |
| CADM2 | cell adhesion molecule 2 | -0.0310696 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0309869 |
| SLMAP | sarcolemma associated protein | -0.030835 |
| RPS19 | ribosomal protein S19 | -0.0306753 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.030376 |
