| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Regorafenib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Regorafenib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.068332 |
| NDRG1 | N-myc downstream regulated 1 | 0.0638904 |
| H1-0 | H1.0 linker histone | 0.054213 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0535702 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.05117 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.049348 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0474387 |
| RNF149 | ring finger protein 149 | 0.0468546 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0389383 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0380925 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.036101 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0344935 |
| ERBIN | erbb2 interacting protein | 0.0334903 |
| ALPK1 | alpha-kinase 1 | 0.0329907 |
| RAD51B | RAD51 paralog B | 0.0315267 |
| MSI2 | musashi RNA-binding protein 2 | 0.0314919 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0306582 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0287487 |
| TXNIP | thioredoxin interacting protein | 0.0283787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0282993 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0270098 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0269761 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0260141 |
| ATP10B | ATPase, class V, type 10B | 0.0258937 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.025846 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0247922 |
| ITGA6 | integrin, alpha 6 | 0.0241504 |
| DIAPH3 | diaphanous-related formin 3 | 0.0238856 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0235721 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.022384 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0217464 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0211828 |
| CCNL1 | cyclin L1 | 0.0208672 |
| FOSL2 | FOS-like antigen 2 | 0.0208463 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0207932 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0206457 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0200653 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0197885 |
| STK39 | serine threonine kinase 39 | 0.0197303 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0196606 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.019605 |
| PFKP | phosphofructokinase, platelet | 0.0195646 |
| ZNF395 | zinc finger protein 395 | 0.0195056 |
| KIF16B | kinesin family member 16B | 0.0194456 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0191246 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0186681 |
| CNOT11 | CCR4-NOT transcription complex, subunit 11 | 0.0185735 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0185371 |
| FAM13A | family with sequence similarity 13, member A | 0.0184054 |
| VEGFA | vascular endothelial growth factor A | 0.018403 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0183116 |
| APOL2 | apolipoprotein L, 2 | 0.0182277 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0182246 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0180334 |
| EFHD2 | EF-hand domain family, member D2 | 0.0174691 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0174606 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0172635 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0172215 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0171599 |
| CORIN | corin, serine peptidase | 0.0167627 |
| TPCN1 | two pore segment channel 1 | 0.01676 |
| SLC22A23 | solute carrier family 22, member 23 | 0.016646 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0166352 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0165306 |
| MYO10 | myosin X | 0.0163764 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0159656 |
| TJP2 | tight junction protein 2 | 0.0159473 |
| SPATA6L | spermatogenesis associated 6-like | 0.0157607 |
| PTEN | phosphatase and tensin homolog | 0.0156366 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0153832 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.015268 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0151345 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0150558 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0149624 |
| XDH | xanthine dehydrogenase | 0.014919 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0147556 |
| CDK19 | cyclin-dependent kinase 19 | 0.0144336 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0144181 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0144154 |
| ARRDC3 | arrestin domain containing 3 | 0.0143951 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0142037 |
| MLPH | melanophilin | 0.014083 |
| ZNF148 | zinc finger protein 148 | 0.0140406 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.013939 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0138558 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0138231 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0138143 |
| TMEM165 | transmembrane protein 165 | 0.0137833 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0137747 |
| CLDN4 | claudin 4 | 0.0134789 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0134206 |
| FGD5 | FYVE, RhoGEF and PH domain containing 5 | 0.0134055 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0133634 |
| MMP24OS | MMP24 opposite strand | 0.0133059 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0132634 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0129531 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0129067 |
| HUNK | hormonally up-regulated Neu-associated kinase | 0.0126485 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0126057 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.0125746 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.191244 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.168915 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.149565 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.104578 |
| INTS6 | integrator complex subunit 6 | -0.0982543 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0970113 |
| ANXA2 | annexin A2 | -0.0943895 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0790653 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0785445 |
| LCN2 | lipocalin 2 | -0.0726162 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0715089 |
| MAP7 | microtubule-associated protein 7 | -0.0710338 |
| PHF3 | PHD finger protein 3 | -0.0709121 |
| FTL | ferritin, light polypeptide | -0.0696548 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0674 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0664163 |
| SQSTM1 | sequestosome 1 | -0.0647153 |
| PERP | PERP, TP53 apoptosis effector | -0.062264 |
| RPS6 | ribosomal protein S6 | -0.0606093 |
| ACTG1 | actin gamma 1 | -0.05751 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0564645 |
| RRBP1 | ribosome binding protein 1 | -0.0557242 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.055705 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0549858 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0548998 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0543095 |
| VCL | vinculin | -0.0531678 |
| GOLGB1 | golgin B1 | -0.0528217 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0523338 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0506381 |
| PKM | pyruvate kinase, muscle | -0.050061 |
| RNF213 | ring finger protein 213 | -0.0493542 |
| EFNB2 | ephrin-B2 | -0.0485083 |
| B2M | beta-2-microglobulin | -0.0477147 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0475067 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0472307 |
| CANX | calnexin | -0.046489 |
| RPL12 | ribosomal protein L12 | -0.0461635 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0454653 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0451999 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0449291 |
| EPCAM | epithelial cell adhesion molecule | -0.044417 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.044243 |
| AHI1 | Abelson helper integration site 1 | -0.0441366 |
| YAP1 | Yes-associated protein 1 | -0.0424395 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.042336 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0421026 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0413166 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0410426 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0409608 |
| RPL34 | ribosomal protein L34 | -0.0400001 |
| RBM39 | RNA binding motif protein 39 | -0.0393965 |
| PLSCR2 | phospholipid scramblase 2 | -0.0389686 |
| RPL23 | ribosomal protein L23 | -0.0388135 |
| XAF1 | XIAP associated factor 1 | -0.0387112 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0386319 |
| LIMA1 | LIM domain and actin binding 1 | -0.0383242 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0382798 |
| RNF43 | ring finger protein 43 | -0.0382503 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0381647 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0380425 |
| RPL35A | ribosomal protein L35a | -0.0374394 |
| SFTPA2 | surfactant protein A2 | -0.0373344 |
| MUC20 | mucin 20, cell surface associated | -0.0373282 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0372956 |
| RPS8 | ribosomal protein S8 | -0.0370879 |
| HLA-B | major histocompatibility complex, class I, B | -0.0370574 |
| TJP1 | tight junction protein 1 | -0.0369622 |
| HM13 | histocompatibility (minor) 13 | -0.0368769 |
| SP100 | SP100 nuclear antigen | -0.0364897 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0355184 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0353195 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0352718 |
| POF1B | premature ovarian failure, 1B | -0.0347472 |
| MYO1E | myosin IE | -0.0347175 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0346849 |
| CLTC | clathrin, heavy chain (Hc) | -0.0346827 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0346488 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.034523 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.034448 |
| IFNGR1 | interferon gamma receptor 1 | -0.0343219 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0342335 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0341642 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0341541 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0339039 |
| RUNX1 | runt-related transcription factor 1 | -0.0337476 |
| JUN | jun proto-oncogene | -0.0332584 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332509 |
| HDLBP | high density lipoprotein binding protein | -0.0330736 |
| DSTN | destrin (actin depolymerizing factor) | -0.0328438 |
| MX1 | MX dynamin-like GTPase 1 | -0.032734 |
| RPL9 | ribosomal protein L9 | -0.032641 |
| RPL19 | ribosomal protein L19 | -0.0323706 |
| RPL31 | ribosomal protein L31 | -0.0322504 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0321158 |
| SERINC5 | serine incorporator 5 | -0.0313494 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0309983 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0307995 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0305969 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0305206 |
