| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Regorafenib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Regorafenib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.25197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.177018 |
| TNS4 | tensin 4 | 0.128357 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.102767 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0854113 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0806356 |
| H1-0 | H1.0 linker histone | 0.0806053 |
| KRT8 | keratin 8, type II | 0.0759213 |
| FAT1 | FAT atypical cadherin 1 | 0.0757642 |
| RNF43 | ring finger protein 43 | 0.0728377 |
| TRIM2 | tripartite motif containing 2 | 0.0672058 |
| ITGA6 | integrin, alpha 6 | 0.0611034 |
| LDHA | lactate dehydrogenase A | 0.0610803 |
| VMP1 | vacuole membrane protein 1 | 0.0593588 |
| CD47 | CD47 molecule | 0.0580419 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0571459 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0565368 |
| TXNIP | thioredoxin interacting protein | 0.0547344 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0495183 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0482451 |
| GPHN | gephyrin | 0.0461032 |
| EZR | ezrin | 0.0446671 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0442096 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0436969 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0429703 |
| NDRG1 | N-myc downstream regulated 1 | 0.0425692 |
| ANXA11 | annexin A11 | 0.0415491 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0413189 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0410374 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0410014 |
| ABHD17C | abhydrolase domain containing 17C | 0.0398653 |
| SETD5 | SET domain containing 5 | 0.0398071 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0396674 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0396217 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0387139 |
| ACTN4 | actinin, alpha 4 | 0.0386593 |
| RNF145 | ring finger protein 145 | 0.0383442 |
| GOLGA4 | golgin A4 | 0.0378067 |
| BCL2L1 | BCL2-like 1 | 0.0375262 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0370849 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0362425 |
| KRT19 | keratin 19, type I | 0.0354287 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0351755 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0351563 |
| RBM39 | RNA binding motif protein 39 | 0.0348293 |
| ANXA2 | annexin A2 | 0.0341245 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0338685 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0336125 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0336012 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0335413 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0332855 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0331901 |
| RPL3 | ribosomal protein L3 | 0.0329457 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0326719 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0324589 |
| KRT18 | keratin 18, type I | 0.0323962 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.031466 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0313843 |
| OGA | O-GlcNAcase | 0.0312431 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0310472 |
| PTK2 | protein tyrosine kinase 2 | 0.0310036 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0308792 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306425 |
| EPHA2 | EPH receptor A2 | 0.0303912 |
| CTBP2 | C-terminal binding protein 2 | 0.0302908 |
| PNN | pinin, desmosome associated protein | 0.0295743 |
| YAP1 | Yes-associated protein 1 | 0.0293741 |
| PTEN | phosphatase and tensin homolog | 0.0292458 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0286186 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0286137 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0285273 |
| FOXJ3 | forkhead box J3 | 0.0284977 |
| ZNF292 | zinc finger protein 292 | 0.0283881 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.028111 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0280338 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279645 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0268762 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0268613 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0267844 |
| CCNL1 | cyclin L1 | 0.0267533 |
| EMP1 | epithelial membrane protein 1 | 0.0266353 |
| NUP58 | nucleoporin 58 | 0.0265828 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0264421 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0260244 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0259853 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0259192 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0256701 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0256525 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0255439 |
| CENPF | centromere protein F, 350/400kDa | 0.0253967 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0253952 |
| COG5 | component of oligomeric golgi complex 5 | 0.0253655 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0253124 |
| PRSS3 | protease, serine, 3 | 0.0246268 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0245899 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.024468 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0243631 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0243526 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0240454 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0237479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.256018 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.135851 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.126856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12206 |
| NPSR1 | neuropeptide S receptor 1 | -0.118159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110461 |
| RPS6 | ribosomal protein S6 | -0.0780334 |
| CANX | calnexin | -0.0764745 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0751799 |
| AHNAK | AHNAK nucleoprotein | -0.0669036 |
| RPLP1 | ribosomal protein, large, P1 | -0.061637 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0590312 |
| LOC112694756 | uncharaterized LOC112694756 | -0.05582 |
| MYO1E | myosin IE | -0.0524056 |
| RPL35A | ribosomal protein L35a | -0.048993 |
| RPS12 | ribosomal protein S12 | -0.047779 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0454235 |
| RPS8 | ribosomal protein S8 | -0.0453827 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.045246 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0446503 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0424892 |
| TPM4 | tropomyosin 4 | -0.041657 |
| TMSB10 | thymosin beta 10 | -0.0405766 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0393766 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0379436 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0377329 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0377233 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.037219 |
| RPL13A | ribosomal protein L13a | -0.0366935 |
| PCBP2 | poly(rC) binding protein 2 | -0.036343 |
| AGR2 | anterior gradient 2 | -0.0357233 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.03482 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.034352 |
| FHIT | fragile histidine triad | -0.0343014 |
| RPS25 | ribosomal protein S25 | -0.0335074 |
| RPL12 | ribosomal protein L12 | -0.0333313 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0329765 |
| RPL34 | ribosomal protein L34 | -0.03279 |
| RPL30 | ribosomal protein L30 | -0.0326794 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0324025 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0321546 |
| RPS2 | ribosomal protein S2 | -0.0314928 |
| S100A6 | S100 calcium binding protein A6 | -0.0314249 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0312281 |
| PGK1 | phosphoglycerate kinase 1 | -0.0312123 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0311948 |
| AHI1 | Abelson helper integration site 1 | -0.0311877 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0310846 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0309939 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0307256 |
| RIGI | RNA sensor RIG-I | -0.0305728 |
| IER3 | immediate early response 3 | -0.0304112 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0299287 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.029853 |
| EPCAM | epithelial cell adhesion molecule | -0.0298319 |
| RPL7A | ribosomal protein L7a | -0.0292181 |
| RNF217 | ring finger protein 217 | -0.0289256 |
| CALR | calreticulin | -0.0288636 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0285641 |
| CCND1 | cyclin D1 | -0.028353 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0282733 |
| XPOT | exportin, tRNA | -0.0277179 |
| RPL37 | ribosomal protein L37 | -0.0276641 |
| TMSB4X | thymosin beta 4, X-linked | -0.0275093 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0274198 |
| RPS13 | ribosomal protein S13 | -0.0272685 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0266074 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0265165 |
| ZNF33A | zinc finger protein 33A | -0.0260868 |
| GNAS | GNAS complex locus | -0.0258912 |
| HDLBP | high density lipoprotein binding protein | -0.0258732 |
| AEBP2 | AE binding protein 2 | -0.0251649 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0250552 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0249948 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0249761 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0246622 |
| FTL | ferritin, light polypeptide | -0.0244661 |
| RTN3 | reticulon 3 | -0.0240426 |
| HDAC2 | histone deacetylase 2 | -0.0239129 |
| RPS27A | ribosomal protein S27a | -0.0235533 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0232669 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0230507 |
| MLEC | malectin | -0.0227888 |
| PALLD | palladin, cytoskeletal associated protein | -0.0226437 |
| RPL36 | ribosomal protein L36 | -0.022539 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0223002 |
| FBXO11 | F-box protein 11 | -0.0221298 |
| PCDH9 | protocadherin 9 | -0.0220769 |
| DIAPH2 | diaphanous-related formin 2 | -0.02205 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0219325 |
| APP | amyloid beta (A4) precursor protein | -0.0218402 |
| UBC | ubiquitin C | -0.0215004 |
| RPS27 | ribosomal protein S27 | -0.0212599 |
| FHL2 | four and a half LIM domains 2 | -0.0211696 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0209442 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0209038 |
| EGFR | epidermal growth factor receptor | -0.0208981 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0207021 |
| RPLP0 | ribosomal protein, large, P0 | -0.0206375 |
| RPS16 | ribosomal protein S16 | -0.0205766 |
