| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Regorafenib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Regorafenib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.154317 |
| DST | dystonin | 0.107272 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0643696 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0583837 |
| EFNA5 | ephrin-A5 | 0.0565516 |
| YEATS2 | YEATS domain containing 2 | 0.0542135 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0492696 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0478239 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0458473 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0450975 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0439156 |
| PRELID2 | PRELI domain containing 2 | 0.0430644 |
| TSC22D1 | TSC22 domain family, member 1 | 0.042229 |
| FMNL2 | formin-like 2 | 0.0421173 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0416537 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0407655 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.040305 |
| RAD51B | RAD51 paralog B | 0.0400967 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0398815 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0390805 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0389406 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0386843 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0383382 |
| PTK2 | protein tyrosine kinase 2 | 0.037723 |
| OGA | O-GlcNAcase | 0.0374568 |
| CENPF | centromere protein F, 350/400kDa | 0.0362576 |
| SQSTM1 | sequestosome 1 | 0.0356632 |
| LDHA | lactate dehydrogenase A | 0.0342823 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0335821 |
| FOXJ3 | forkhead box J3 | 0.0332534 |
| ZNF292 | zinc finger protein 292 | 0.0319038 |
| PKM | pyruvate kinase, muscle | 0.0318976 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0312031 |
| EXOC4 | exocyst complex component 4 | 0.0306617 |
| SET | SET nuclear proto-oncogene | 0.0305014 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0304904 |
| SMYD3 | SET and MYND domain containing 3 | 0.0300865 |
| TNS3 | tensin 3 | 0.0298983 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0298724 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0297572 |
| FLNB | filamin B, beta | 0.0291278 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0289823 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0287465 |
| HLA-B | major histocompatibility complex, class I, B | 0.0287086 |
| ENO1 | enolase 1, (alpha) | 0.0284562 |
| ZNF148 | zinc finger protein 148 | 0.0284103 |
| CCNL1 | cyclin L1 | 0.028382 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0283137 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0282284 |
| RBM39 | RNA binding motif protein 39 | 0.0279985 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0278447 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0270077 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0268522 |
| B2M | beta-2-microglobulin | 0.0265455 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0265264 |
| MYO10 | myosin X | 0.0264048 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0261185 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0260551 |
| RNF213 | ring finger protein 213 | 0.0257611 |
| DENND1A | DENN/MADD domain containing 1A | 0.0254223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0252797 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0251445 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0251135 |
| VEGFA | vascular endothelial growth factor A | 0.0251095 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0245811 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0241592 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0237663 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0236843 |
| ASPH | aspartate beta-hydroxylase | 0.0236582 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0235174 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0233621 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0232831 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.023108 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0230317 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0230248 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0230033 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0227966 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0226688 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.022589 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0225665 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0223985 |
| RPL35A | ribosomal protein L35a | 0.0223296 |
| RPL3 | ribosomal protein L3 | 0.0222932 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0222891 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0222792 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0222522 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0222055 |
| ITGB4 | integrin, beta 4 | 0.0218843 |
| CDK19 | cyclin-dependent kinase 19 | 0.0218132 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0217859 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0216352 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0216119 |
| NDRG1 | N-myc downstream regulated 1 | 0.0216025 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0215969 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0215967 |
| TPR | translocated promoter region, nuclear basket protein | 0.0215755 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0214705 |
| DOCK11 | dedicator of cytokinesis 11 | 0.021379 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0212903 |
| RPS27A | ribosomal protein S27a | 0.0211635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281646 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.166729 |
| LOC112694756 | uncharaterized LOC112694756 | -0.128212 |
| TXNRD1 | thioredoxin reductase 1 | -0.116414 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.114811 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.114416 |
| VIM | vimentin | -0.104463 |
| TMSB10 | thymosin beta 10 | -0.0897127 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0756854 |
| AHNAK | AHNAK nucleoprotein | -0.0732353 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.068798 |
| MT2A | metallothionein 2A | -0.067465 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0647257 |
| TMSB4X | thymosin beta 4, X-linked | -0.0603681 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0603225 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0598996 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0512305 |
| HMGA1 | high mobility group AT-hook 1 | -0.0503327 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0497102 |
| TMEM41B | transmembrane protein 41B | -0.0474458 |
| CANX | calnexin | -0.0471203 |
| MT1X | metallothionein 1X | -0.0466701 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.046136 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.046063 |
| JUN | jun proto-oncogene | -0.0457279 |
| UBC | ubiquitin C | -0.0455558 |
| EREG | epiregulin | -0.0447034 |
| POTEF | POTE ankyrin domain family, member F | -0.0444441 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0439813 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0424032 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0423017 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0409031 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0408297 |
| ACTG1 | actin gamma 1 | -0.0405512 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0404796 |
| RPL12 | ribosomal protein L12 | -0.0401493 |
| HDLBP | high density lipoprotein binding protein | -0.039919 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039867 |
| CD44 | CD44 molecule (Indian blood group) | -0.0398316 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.039721 |
| TP63 | tumor protein p63 | -0.0390477 |
| FBXO11 | F-box protein 11 | -0.0382409 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0373344 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.037223 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0355963 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0344996 |
| MT1E | metallothionein 1E | -0.0334795 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0331502 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0327489 |
| PYGB | phosphorylase, glycogen; brain | -0.0324207 |
| RUNX1 | runt-related transcription factor 1 | -0.0323733 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0323575 |
| JMJD1C | jumonji domain containing 1C | -0.0323191 |
| RPLP0 | ribosomal protein, large, P0 | -0.03058 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0304757 |
| RPL28 | ribosomal protein L28 | -0.0304199 |
| EGR1 | early growth response 1 | -0.0295453 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0292613 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0291314 |
| S100A6 | S100 calcium binding protein A6 | -0.0279892 |
| TUBB | tubulin, beta class I | -0.0276568 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.027605 |
| SEPTIN7 | septin 7 | -0.0273028 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0264788 |
| TAOK1 | TAO kinase 1 | -0.0263989 |
| RPL4 | ribosomal protein L4 | -0.0263979 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0257872 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0257086 |
| GAN | gigaxonin | -0.0256196 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0255016 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0253559 |
| IPO7 | importin 7 | -0.025346 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.025313 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0252823 |
| SGMS2 | sphingomyelin synthase 2 | -0.025064 |
| RPL35 | ribosomal protein L35 | -0.0250514 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0246896 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0246878 |
| ARF1 | ADP-ribosylation factor 1 | -0.0246403 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0244397 |
| RPS8 | ribosomal protein S8 | -0.0241264 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0238631 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0238107 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0237304 |
| ERBIN | erbb2 interacting protein | -0.023704 |
| TAPBP | TAP binding protein (tapasin) | -0.0236196 |
| CDCP1 | CUB domain containing protein 1 | -0.0230585 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0228315 |
| CLTC | clathrin, heavy chain (Hc) | -0.0224601 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.022203 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0220406 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0214449 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0212893 |
| SEC24A | SEC24 family member A | -0.0209512 |
| TPI1 | triosephosphate isomerase 1 | -0.0207921 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0207606 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0207387 |
| RASA2 | RAS p21 protein activator 2 | -0.0206123 |
| USP12 | ubiquitin specific peptidase 12 | -0.0204048 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0203273 |
