| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Regorafenib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Regorafenib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.167635 |
| COL6A3 | collagen, type VI, alpha 3 | 0.1132 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.110557 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0979021 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0824245 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0822289 |
| SPAG9 | sperm associated antigen 9 | 0.0685898 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0660569 |
| COL1A2 | collagen, type I, alpha 2 | 0.0647585 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0633309 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0628986 |
| COPA | coatomer protein complex, subunit alpha | 0.0614196 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0576107 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0574925 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0573603 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0564877 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0547331 |
| LOX | lysyl oxidase | 0.0520826 |
| CDH13 | cadherin 13 | 0.0515535 |
| SDC4 | syndecan 4 | 0.0508422 |
| FN1 | fibronectin 1 | 0.0508418 |
| ECE1 | endothelin converting enzyme 1 | 0.0507447 |
| ENO1 | enolase 1, (alpha) | 0.0500315 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0486151 |
| IL6 | interleukin 6 | 0.0483711 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0480128 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0476767 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0476286 |
| PGK1 | phosphoglycerate kinase 1 | 0.0474584 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0449856 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0441446 |
| PCBP2 | poly(rC) binding protein 2 | 0.0439148 |
| HMGA2 | high mobility group AT-hook 2 | 0.0436114 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0430163 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0427718 |
| HIP1 | huntingtin interacting protein 1 | 0.0420689 |
| NRXN3 | neurexin 3 | 0.0418474 |
| IKBIP | IKBKB interacting protein | 0.0418233 |
| HELZ | helicase with zinc finger | 0.0406855 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0393638 |
| YME1L1 | YME1-like 1 ATPase | 0.038988 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0389774 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0384912 |
| EMP1 | epithelial membrane protein 1 | 0.038408 |
| TPR | translocated promoter region, nuclear basket protein | 0.038265 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.037757 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0375403 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0374679 |
| PRKD3 | protein kinase D3 | 0.037459 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0371467 |
| RBM39 | RNA binding motif protein 39 | 0.0366252 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0359919 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0353179 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0344954 |
| SRP54 | signal recognition particle 54kDa | 0.033986 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0338322 |
| USP34 | ubiquitin specific peptidase 34 | 0.0337853 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0337592 |
| ERBIN | erbb2 interacting protein | 0.0337235 |
| FLOT1 | flotillin 1 | 0.0336497 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0333277 |
| STC1 | stanniocalcin 1 | 0.0332858 |
| RHEB | Ras homolog enriched in brain | 0.0329235 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0328406 |
| RLF | rearranged L-myc fusion | 0.0326583 |
| VEGFA | vascular endothelial growth factor A | 0.0325413 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0325112 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.032016 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0318404 |
| HLA-A | major histocompatibility complex, class I, A | 0.0318178 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0317347 |
| ATP13A3 | ATPase type 13A3 | 0.0311746 |
| FNBP4 | formin binding protein 4 | 0.0311544 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.030947 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0306941 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0303105 |
| EFNA5 | ephrin-A5 | 0.0302692 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0300743 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0300728 |
| USP3 | ubiquitin specific peptidase 3 | 0.0300699 |
| COL1A1 | collagen, type I, alpha 1 | 0.0300372 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0297951 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0297309 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0295579 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0294352 |
| FLNB | filamin B, beta | 0.0292756 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0291745 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0288383 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0286347 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0285846 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0285233 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0282909 |
| PHF20 | PHD finger protein 20 | 0.0282505 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0281495 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0279978 |
| CD164 | CD164 molecule, sialomucin | 0.0278273 |
| FRMD4A | FERM domain containing 4A | 0.0277802 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0277634 |
| FBXO7 | F-box protein 7 | 0.0277592 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0275769 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.173665 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0926962 |
| MT2A | metallothionein 2A | -0.0855285 |
| RPL11 | ribosomal protein L11 | -0.0786005 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0768006 |
| VCL | vinculin | -0.06687 |
| FTL | ferritin, light polypeptide | -0.0633453 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0628437 |
| B2M | beta-2-microglobulin | -0.0571842 |
| CALD1 | caldesmon 1 | -0.05431 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.052675 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.050925 |
| HLA-B | major histocompatibility complex, class I, B | -0.0502759 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0500742 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0497975 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0468656 |
| MYOF | myoferlin | -0.0467832 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0456822 |
| DST | dystonin | -0.0455674 |
| MEF2A | myocyte enhancer factor 2A | -0.0449617 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0446964 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0442346 |
| RTN4 | reticulon 4 | -0.0437025 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0433678 |
| PRELID2 | PRELI domain containing 2 | -0.0433003 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0414789 |
| HDLBP | high density lipoprotein binding protein | -0.041353 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0412866 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0410733 |
| GSE1 | Gse1 coiled-coil protein | -0.0410295 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0406275 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0404124 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0403436 |
| RPL15 | ribosomal protein L15 | -0.0402548 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0398053 |
| RAD51B | RAD51 paralog B | -0.039684 |
| CD44 | CD44 molecule (Indian blood group) | -0.0390945 |
| LAMB1 | laminin, beta 1 | -0.0383912 |
| EXOC6B | exocyst complex component 6B | -0.0380088 |
| ZNF395 | zinc finger protein 395 | -0.0376691 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0376097 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0372971 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0366456 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0366361 |
| SMYD3 | SET and MYND domain containing 3 | -0.0360673 |
| RPS2 | ribosomal protein S2 | -0.0360087 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.035656 |
| ANKRD17 | ankyrin repeat domain 17 | -0.034938 |
| MORF4L2 | mortality factor 4 like 2 | -0.0342874 |
| H3-3B | H3.3 histone B | -0.0341911 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0341678 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0337696 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0336658 |
| JAK1 | Janus kinase 1 | -0.0336128 |
| RPS5 | ribosomal protein S5 | -0.0335771 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0330618 |
| PRKCA | protein kinase C, alpha | -0.032873 |
| BSG | basigin (Ok blood group) | -0.0321953 |
| ZNF736 | zinc finger protein 736 | -0.0319385 |
| USP8 | ubiquitin specific peptidase 8 | -0.0318099 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0315964 |
| MTPN | myotrophin | -0.0315087 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0313107 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0311552 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0306963 |
| FAM13B | family with sequence similarity 13, member B | -0.0304363 |
| PHF21A | PHD finger protein 21A | -0.0297475 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0296929 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0293628 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0292972 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0292937 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0292789 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.02909 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0290288 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0289102 |
| USP33 | ubiquitin specific peptidase 33 | -0.0288705 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0288029 |
| MYLK | myosin light chain kinase | -0.0286983 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0286125 |
| EGFR | epidermal growth factor receptor | -0.0285377 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0283775 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0281138 |
| PALLD | palladin, cytoskeletal associated protein | -0.0281066 |
| SRPK2 | SRSF protein kinase 2 | -0.0280305 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0279787 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0276388 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0275808 |
| CLIC4 | chloride intracellular channel 4 | -0.0275096 |
| PTGES2 | prostaglandin E synthase 2 | -0.0274769 |
| CCDC88A | coiled-coil domain containing 88A | -0.0274653 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0273111 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0272033 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0269813 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0266577 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0266553 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0261544 |
| KIF5B | kinesin family member 5B | -0.0258791 |
| RPS12 | ribosomal protein S12 | -0.0256801 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0254732 |
| MRPS27 | mitochondrial ribosomal protein S27 | -0.0253459 |
