| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Regorafenib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Regorafenib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.120325 |
| NDRG1 | N-myc downstream regulated 1 | 0.110689 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.106469 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0767545 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0741546 |
| CD109 | CD109 molecule | 0.0736577 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0705709 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0690032 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0682364 |
| PLIN2 | perilipin 2 | 0.0666767 |
| FAM13A | family with sequence similarity 13, member A | 0.063445 |
| VEGFA | vascular endothelial growth factor A | 0.0616761 |
| ITGA1 | integrin, alpha 1 | 0.0591011 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0574072 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0547944 |
| HMGA2 | high mobility group AT-hook 2 | 0.0526624 |
| PTMA | prothymosin, alpha | 0.0523341 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0514794 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0485382 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0458123 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0427041 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0399226 |
| NRG1 | neuregulin 1 | 0.0398122 |
| RNF145 | ring finger protein 145 | 0.0384799 |
| ENO1 | enolase 1, (alpha) | 0.0357832 |
| UBC | ubiquitin C | 0.0342562 |
| HMGB3 | high mobility group box 3 | 0.0331757 |
| TMEM165 | transmembrane protein 165 | 0.0328105 |
| STC2 | stanniocalcin 2 | 0.0319847 |
| FOSL1 | FOS-like antigen 1 | 0.0313763 |
| HDGF | hepatoma-derived growth factor | 0.0307719 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0296828 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0294162 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0292912 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0286501 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0284595 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0271938 |
| ZNF292 | zinc finger protein 292 | 0.0266993 |
| PCBP2 | poly(rC) binding protein 2 | 0.0264046 |
| INSIG2 | insulin induced gene 2 | 0.0262313 |
| PER1 | period circadian clock 1 | 0.0261029 |
| PRELID2 | PRELI domain containing 2 | 0.0256238 |
| SMOX | spermine oxidase | 0.0256136 |
| SRP54 | signal recognition particle 54kDa | 0.0254967 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0254752 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0253181 |
| CANX | calnexin | 0.0252081 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0245776 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0244101 |
| RUNX2 | runt-related transcription factor 2 | 0.0243875 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0242732 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0241955 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0241497 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0234725 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0233131 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0228482 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0227565 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0225477 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0224256 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0224156 |
| PKM | pyruvate kinase, muscle | 0.0223184 |
| RPL4 | ribosomal protein L4 | 0.0221465 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0221084 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.021713 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0217085 |
| PGK1 | phosphoglycerate kinase 1 | 0.0213685 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0204876 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0203757 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.01979 |
| SFXN1 | sideroflexin 1 | 0.0197261 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0194502 |
| CALR | calreticulin | 0.0192669 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0189002 |
| TPM3 | tropomyosin 3 | 0.0186645 |
| RPL13A | ribosomal protein L13a | 0.0186287 |
| CCNL1 | cyclin L1 | 0.0186081 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0185106 |
| BSG | basigin (Ok blood group) | 0.0182906 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0182109 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0180305 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0180012 |
| SFMBT2 | Scm-like with four mbt domains 2 | 0.0179945 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0176579 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0172889 |
| HELZ | helicase with zinc finger | 0.0168864 |
| COPA | coatomer protein complex, subunit alpha | 0.016879 |
| RNF24 | ring finger protein 24 | 0.0167218 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0164351 |
| FOSL2 | FOS-like antigen 2 | 0.0163062 |
| FAM20C | family with sequence similarity 20, member C | 0.0162993 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0162352 |
| ATG14 | autophagy related 14 | 0.016204 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0161765 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0156734 |
| PFN1 | profilin 1 | 0.0154958 |
| FLNB | filamin B, beta | 0.0154799 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0153875 |
| FAM193B | family with sequence similarity 193, member B | 0.0153717 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0153652 |
| PFKP | phosphofructokinase, platelet | 0.0151298 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.299297 |
| EXT1 | exostosin glycosyltransferase 1 | -0.162683 |
| ASPH | aspartate beta-hydroxylase | -0.0918047 |
| SFTPA2 | surfactant protein A2 | -0.0911667 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0819746 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0756797 |
| VCL | vinculin | -0.0734225 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0686269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0673371 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0653808 |
| FN1 | fibronectin 1 | -0.0653604 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0612652 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.060515 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0602019 |
| JMJD1C | jumonji domain containing 1C | -0.0597423 |
| SMYD3 | SET and MYND domain containing 3 | -0.05832 |
| TMEM156 | transmembrane protein 156 | -0.0558601 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0557327 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0544821 |
| SVIL | supervillin | -0.050992 |
| OSMR | oncostatin M receptor | -0.0496515 |
| MAP1B | microtubule-associated protein 1B | -0.049647 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0496273 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0487621 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0476859 |
| MT2A | metallothionein 2A | -0.0476362 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.046999 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0461434 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0454072 |
| CLTC | clathrin, heavy chain (Hc) | -0.0448616 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0400464 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0398776 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0393508 |
| IL6ST | interleukin 6 signal transducer | -0.0388639 |
| DST | dystonin | -0.0388101 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0387658 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0386298 |
| AHR | aryl hydrocarbon receptor | -0.0385308 |
| HLA-B | major histocompatibility complex, class I, B | -0.0374651 |
| RAB10 | RAB10, member RAS oncogene family | -0.0374626 |
| TXNRD1 | thioredoxin reductase 1 | -0.0372377 |
| FTL | ferritin, light polypeptide | -0.0368293 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0359921 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0358879 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0353204 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0352761 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0351941 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0345724 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.034147 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0335833 |
| S100A10 | S100 calcium binding protein A10 | -0.0333765 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0333522 |
| ARF1 | ADP-ribosylation factor 1 | -0.0331744 |
| FOXP1 | forkhead box P1 | -0.0330766 |
| PALLD | palladin, cytoskeletal associated protein | -0.0329268 |
| RPL38 | ribosomal protein L38 | -0.0322216 |
| APP | amyloid beta (A4) precursor protein | -0.0320656 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0320468 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0317967 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0317446 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0317214 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0316063 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0314073 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0313783 |
| GOLT1B | golgi transport 1B | -0.0311476 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0308029 |
| RPS24 | ribosomal protein S24 | -0.030565 |
| RBM39 | RNA binding motif protein 39 | -0.0303258 |
| RASAL2 | RAS protein activator like 2 | -0.0301806 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.030172 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0296239 |
| NEK7 | NIMA-related kinase 7 | -0.0281854 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0281733 |
| NTN4 | netrin 4 | -0.0281195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0276794 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0276772 |
| ACTG1 | actin gamma 1 | -0.0272965 |
| ATF6 | activating transcription factor 6 | -0.0272301 |
| ZNF217 | zinc finger protein 217 | -0.0272086 |
| SEPTIN9 | septin 9 | -0.0271593 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0269356 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0269054 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0268989 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0267426 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0267303 |
| NCOA7 | nuclear receptor coactivator 7 | -0.026657 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0266022 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0265434 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0264736 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0264247 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0263963 |
| CEP350 | centrosomal protein 350kDa | -0.026329 |
| RANBP17 | RAN binding protein 17 | -0.0261552 |
| DNM1L | dynamin 1-like | -0.0257906 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0255781 |
| CENPF | centromere protein F, 350/400kDa | -0.0255677 |
| SIK3 | SIK family kinase 3 | -0.0253568 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0252754 |
| GPHN | gephyrin | -0.0251451 |
| EMP1 | epithelial membrane protein 1 | -0.025068 |
