Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-381426
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Genes

124 proteins participating in the Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
AFP alpha-fetoprotein
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMBN ameloblastin (enamel matrix protein)
AMELX amelogenin, X-linked
AMTN amelotin
ANO8 anoctamin 8
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
APP amyloid beta (A4) precursor protein
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
BPIFB2 BPI fold containing family B, member 2
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
CALU calumenin
CCN1 cellular communication network factor 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHGB chromogranin B
CHRDL1 chordin-like 1
CKAP4 cytoskeleton-associated protein 4
CP ceruloplasmin (ferroxidase)
CSF1 colony stimulating factor 1 (macrophage)
CST3 cystatin C
CTSG cathepsin G
DMP1 dentin matrix acidic phosphoprotein 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ENAM enamelin
EVA1A eva-1 homolog A (C. elegans)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAM20A family with sequence similarity 20, member A
FAM20C family with sequence similarity 20, member C
FBN1 fibrillin 1
FGA fibrinogen alpha chain
FGF23 fibroblast growth factor 23
FGG fibrinogen gamma chain
FN1 fibronectin 1
FSTL1 follistatin-like 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUCA2 fucosidase, alpha-L- 2, plasma
GAS6 growth arrest-specific 6
GOLM1 golgi membrane protein 1
GPC3 glypican 3
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HRC histidine rich calcium binding protein
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IGFBP7 insulin-like growth factor binding protein 7
IL6 interleukin 6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KLK1 kallikrein 1
KLK13 kallikrein-related peptidase 13
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KNG1 kininogen 1
KTN1 kinectin 1 (kinesin receptor)
LAMB1 laminin, beta 1
LAMB2 laminin, beta 2 (laminin S)
LAMC1 laminin, gamma 1 (formerly LAMB2)
LGALS1 lectin, galactoside-binding, soluble, 1
LTBP1 latent transforming growth factor beta binding protein 1
MATN3 matrilin 3
MBTPS1 membrane-bound transcription factor peptidase, site 1
MELTF melanotransferrin
MEN1 multiple endocrine neoplasia I
MEPE matrix extracellular phosphoglycoprotein
MFGE8 milk fat globule-EGF factor 8 protein
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MIA3 melanoma inhibitory activity family, member 3
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MSLN mesothelin
MXRA8 matrix-remodelling associated 8
NOTUM notum pectinacetylesterase homolog (Drosophila)
NUCB1 nucleobindin 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PCSK9 proprotein convertase subtilisin/kexin type 9
PDIA6 protein disulfide isomerase family A, member 6
PENK proenkephalin
PLG plasminogen
PNPLA2 patatin-like phospholipase domain containing 2
PRKCSH protein kinase C substrate 80K-H
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRSS23 protease, serine, 23
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SCG2 secretogranin II
SCG3 secretogranin III
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SHISA5 shisa family member 5
SPARCL1 SPARC-like 1 (hevin)
SPP1 secreted phosphoprotein 1
SPP2 secreted phosphoprotein 2, 24kDa
STC2 stanniocalcin 2
TF transferrin
TGOLN2 trans-golgi network protein 2
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM132A transmembrane protein 132A
TNC tenascin C
VCAN versican
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WFS1 Wolfram syndrome 1 (wolframin)