Regulation of necroptotic cell death Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5675482
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Genes

32 proteins participating in the Regulation of necroptotic cell death pathway from the Reactome Pathways 2024 dataset.

Symbol Name
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDC37 cell division cycle 37
CFLAR CASP8 and FADD-like apoptosis regulator
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FLOT1 flotillin 1
FLOT2 flotillin 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ITCH itchy E3 ubiquitin protein ligase
MLKL mixed lineage kinase domain-like
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PDCD6IP programmed cell death 6 interacting protein
PELI1 pellino E3 ubiquitin protein ligase 1
PRKN parkin RBR E3 ubiquitin protein ligase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RPS27A ribosomal protein S27a
SDCBP syndecan binding protein (syntenin)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2L3 ubiquitin-conjugating enzyme E2L 3
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase