| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Relugolix perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Relugolix_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0975834 |
| PKM | pyruvate kinase, muscle | 0.0887458 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0851223 |
| FOXP1 | forkhead box P1 | 0.0802915 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0732589 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0643326 |
| HDAC9 | histone deacetylase 9 | 0.0628676 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0595235 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0570321 |
| TXNRD1 | thioredoxin reductase 1 | 0.0557183 |
| PYGB | phosphorylase, glycogen; brain | 0.0521287 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0508343 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0424624 |
| POTEF | POTE ankyrin domain family, member F | 0.0421788 |
| GSE1 | Gse1 coiled-coil protein | 0.0415463 |
| TJP1 | tight junction protein 1 | 0.041426 |
| NF1 | neurofibromin 1 | 0.0414209 |
| GLI3 | GLI family zinc finger 3 | 0.0390923 |
| RTN4 | reticulon 4 | 0.0387876 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0382795 |
| EGFR | epidermal growth factor receptor | 0.0380369 |
| RPL3 | ribosomal protein L3 | 0.0379223 |
| TRERF1 | transcriptional regulating factor 1 | 0.0369346 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0362962 |
| LOXL3 | lysyl oxidase-like 3 | 0.034769 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0344411 |
| FLNB | filamin B, beta | 0.0339258 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0336268 |
| USP34 | ubiquitin specific peptidase 34 | 0.0330292 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0329514 |
| GPHN | gephyrin | 0.0326422 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.032313 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0319783 |
| NBAS | neuroblastoma amplified sequence | 0.0315722 |
| JMJD1C | jumonji domain containing 1C | 0.0314706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0313238 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0307213 |
| CCNL1 | cyclin L1 | 0.0303606 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0302991 |
| RBM25 | RNA binding motif protein 25 | 0.0299694 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0298078 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0292622 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.029212 |
| SRPK2 | SRSF protein kinase 2 | 0.0290917 |
| PTK2 | protein tyrosine kinase 2 | 0.0290915 |
| SLMAP | sarcolemma associated protein | 0.0290057 |
| RIGI | RNA sensor RIG-I | 0.0289923 |
| VMP1 | vacuole membrane protein 1 | 0.0289813 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0289653 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0288245 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0286956 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0286266 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0283126 |
| DGKH | diacylglycerol kinase, eta | 0.0281482 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0279923 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0274789 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0273406 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0269167 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0267335 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.026412 |
| MYO5C | myosin VC | 0.0260288 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0256612 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0254647 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0252331 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0250049 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0246732 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0244085 |
| EZR | ezrin | 0.0240944 |
| SMYD3 | SET and MYND domain containing 3 | 0.0239534 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0239484 |
| MATR3 | matrin 3 | 0.0238808 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0236385 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0236047 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0234805 |
| ZNF638 | zinc finger protein 638 | 0.0231121 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.023041 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0230242 |
| FTO | fat mass and obesity associated | 0.0227146 |
| SEPTIN9 | septin 9 | 0.0225922 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.022544 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0224977 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.022329 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0222054 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0221612 |
| NCKAP1 | NCK-associated protein 1 | 0.0220761 |
| EXOC6B | exocyst complex component 6B | 0.0220658 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0219779 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0218019 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0216639 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0216507 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0215969 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0215641 |
| VCL | vinculin | 0.021549 |
| ATP9B | ATPase, class II, type 9B | 0.0214732 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0214371 |
| NBEA | neurobeachin | 0.0212723 |
| MED13L | mediator complex subunit 13-like | 0.0211274 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0211189 |
| ZNF148 | zinc finger protein 148 | 0.0211188 |
| GLI2 | GLI family zinc finger 2 | 0.0211012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.252058 |
| PTMA | prothymosin, alpha | -0.110271 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0978977 |
| BMP10 | bone morphogenetic protein 10 | -0.0944011 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0942493 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0799812 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0716447 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0649207 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644482 |
| PRELID2 | PRELI domain containing 2 | -0.0461575 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0417108 |
| RPL9 | ribosomal protein L9 | -0.0415435 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0415156 |
| RPS8 | ribosomal protein S8 | -0.0400661 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0395956 |
| CENPF | centromere protein F, 350/400kDa | -0.0390886 |
| RPL34 | ribosomal protein L34 | -0.0369301 |
| MKI67 | marker of proliferation Ki-67 | -0.0361764 |
| INTS6 | integrator complex subunit 6 | -0.0339959 |
| CCND1 | cyclin D1 | -0.0334831 |
| CANX | calnexin | -0.0324894 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0313662 |
| HJURP | Holliday junction recognition protein | -0.0309094 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0307715 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0302393 |
| LDHA | lactate dehydrogenase A | -0.029906 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0295743 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0293951 |
| NEBL | nebulette | -0.0292304 |
| TPX2 | TPX2, microtubule-associated | -0.0283961 |
| TUBB | tubulin, beta class I | -0.0283503 |
| AHNAK | AHNAK nucleoprotein | -0.0279853 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0279112 |
| RPL35A | ribosomal protein L35a | -0.0276555 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0274271 |
| PGK1 | phosphoglycerate kinase 1 | -0.0272311 |
| KIAA1958 | KIAA1958 | -0.0265175 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0261818 |
| NAV2 | neuron navigator 2 | -0.0254344 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0253122 |
| RPL31 | ribosomal protein L31 | -0.0252211 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0250286 |
| DIAPH3 | diaphanous-related formin 3 | -0.0248458 |
| RPS24 | ribosomal protein S24 | -0.024511 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0242456 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0237081 |
| ZNF217 | zinc finger protein 217 | -0.0233949 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0228149 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0226741 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0223214 |
| CLIC4 | chloride intracellular channel 4 | -0.0217184 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0215098 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.021409 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0212882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0210318 |
| RRBP1 | ribosome binding protein 1 | -0.0208705 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0207204 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.020685 |
| SQSTM1 | sequestosome 1 | -0.0206802 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0206579 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0205225 |
| RPL12 | ribosomal protein L12 | -0.0204495 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0202208 |
| ANLN | anillin, actin binding protein | -0.0201843 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0198545 |
| TUBA1B | tubulin, alpha 1b | -0.0197399 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0196401 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0191376 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0190727 |
| SCFD1 | sec1 family domain containing 1 | -0.0189916 |
| RPL26 | ribosomal protein L26 | -0.0188753 |
| ACTG1 | actin gamma 1 | -0.018851 |
| FER1L6 | fer-1-like family member 6 | -0.0185919 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0183924 |
| FTL | ferritin, light polypeptide | -0.0183718 |
| PHF3 | PHD finger protein 3 | -0.0183692 |
| ECT2 | epithelial cell transforming 2 | -0.0182183 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.018045 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0179941 |
| SNX14 | sorting nexin 14 | -0.0179359 |
| CENPE | centromere protein E, 312kDa | -0.0178545 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0175751 |
| ENO1 | enolase 1, (alpha) | -0.0175146 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0174611 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0173464 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0172453 |
| ASPH | aspartate beta-hydroxylase | -0.0172377 |
| EMP3 | epithelial membrane protein 3 | -0.0170759 |
| RPS19 | ribosomal protein S19 | -0.0169524 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0168443 |
| SACK1D | scaffolding CK1 anchoring protein D | -0.0168216 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0167933 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0167418 |
| RPS12 | ribosomal protein S12 | -0.0166581 |
| HM13 | histocompatibility (minor) 13 | -0.0166569 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0166242 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0163185 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.016317 |
| RPL37 | ribosomal protein L37 | -0.0163045 |
| TBCA | tubulin folding cofactor A | -0.01622 |
