| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Relugolix perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Relugolix_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0592045 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0539674 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0472881 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.043644 |
| VMP1 | vacuole membrane protein 1 | 0.0374708 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0319843 |
| MSN | moesin | 0.0310914 |
| VCL | vinculin | 0.0300665 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0299121 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0276356 |
| MLPH | melanophilin | 0.0266082 |
| INTS6 | integrator complex subunit 6 | 0.0243155 |
| SMAD3 | SMAD family member 3 | 0.0238827 |
| HDAC9 | histone deacetylase 9 | 0.0236447 |
| BICC1 | BicC family RNA binding protein 1 | 0.0236226 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.021584 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0210145 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0200474 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.019599 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.019348 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0189281 |
| BRD2 | bromodomain containing 2 | 0.0186032 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.01859 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0177286 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0176757 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0169942 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0169174 |
| KYNU | kynureninase | 0.0168139 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0166255 |
| AHR | aryl hydrocarbon receptor | 0.0161495 |
| FMNL2 | formin-like 2 | 0.015994 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0158114 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0154065 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0153465 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0150998 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0150397 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0148878 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0148322 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0148304 |
| NABP1 | nucleic acid binding protein 1 | 0.0146217 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0142367 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0134121 |
| RPL3 | ribosomal protein L3 | 0.0132203 |
| WDR27 | WD repeat domain 27 | 0.0129246 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0125389 |
| NEK7 | NIMA-related kinase 7 | 0.0124596 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0121519 |
| PHF14 | PHD finger protein 14 | 0.0119048 |
| TUT7 | terminal uridylyl transferase 7 | 0.0116361 |
| EGFR | epidermal growth factor receptor | 0.0115239 |
| NOTCH2 | notch 2 | 0.0112772 |
| TGM2 | transglutaminase 2 | 0.0109769 |
| SMAD2 | SMAD family member 2 | 0.010812 |
| DUSP10 | dual specificity phosphatase 10 | 0.0106946 |
| EVC | Ellis van Creveld protein | 0.0105599 |
| PCDH7 | protocadherin 7 | 0.010555 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.010538 |
| ZNF638 | zinc finger protein 638 | 0.0105366 |
| ANO6 | anoctamin 6 | 0.0105018 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0102927 |
| ATXN1 | ataxin 1 | 0.01027 |
| JAK2 | Janus kinase 2 | 0.010238 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0101628 |
| FHL2 | four and a half LIM domains 2 | 0.0101422 |
| LYST | lysosomal trafficking regulator | 0.0100236 |
| CAPRIN2 | caprin family member 2 | 0.010022 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.00999657 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.00999114 |
| TNS1 | tensin 1 | 0.00996793 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00991709 |
| RUNX1 | runt-related transcription factor 1 | 0.0099139 |
| TMEM132D | transmembrane protein 132D | 0.00988543 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00985629 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.00982316 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00976318 |
| KSR1 | kinase suppressor of ras 1 | 0.00970574 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00952678 |
| CCNL1 | cyclin L1 | 0.00947746 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.00945521 |
| DUSP16 | dual specificity phosphatase 16 | 0.00943866 |
| RASEF | RAS and EF-hand domain containing | 0.00939909 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.00939765 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.00931144 |
| GLIS3 | GLIS family zinc finger 3 | 0.00930839 |
| KLHL29 | kelch-like family member 29 | 0.00927949 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00925545 |
| KIAA1217 | KIAA1217 | 0.00922833 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00922149 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00920253 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.00918819 |
| FRMD6 | FERM domain containing 6 | 0.00916648 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.00915074 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.00912201 |
| MRTFA | myocardin related transcription factor A | 0.00909991 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.00890827 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00881484 |
| IDS | iduronate 2-sulfatase | 0.0087708 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00865961 |
| FAM219A | family with sequence similarity 219, member A | 0.00859967 |
| CCNY | cyclin Y | 0.00855524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.371768 |
| HLA-B | major histocompatibility complex, class I, B | -0.15246 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.112901 |
| TMSB10 | thymosin beta 10 | -0.0967973 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0956442 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0790232 |
| FN1 | fibronectin 1 | -0.0788443 |
| PGK1 | phosphoglycerate kinase 1 | -0.070533 |
| FTL | ferritin, light polypeptide | -0.0703422 |
| IER3 | immediate early response 3 | -0.0701852 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0680541 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0662767 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0608098 |
| TPM4 | tropomyosin 4 | -0.0603998 |
| PTMA | prothymosin, alpha | -0.0600878 |
| RPS6 | ribosomal protein S6 | -0.0573694 |
| HLA-A | major histocompatibility complex, class I, A | -0.0555122 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0550369 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0547917 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0547387 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0537453 |
| RPS24 | ribosomal protein S24 | -0.0517944 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0511273 |
| HLA-E | major histocompatibility complex, class I, E | -0.0495123 |
| FNDC3B | fibronectin type III domain containing 3B | -0.048826 |
| RPL23 | ribosomal protein L23 | -0.0477048 |
| CD44 | CD44 molecule (Indian blood group) | -0.0474474 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.047205 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0462472 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0462023 |
| GNAS | GNAS complex locus | -0.0460708 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0445774 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0445044 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0435239 |
| AHNAK | AHNAK nucleoprotein | -0.0434079 |
| ADM | adrenomedullin | -0.0427934 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0427211 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0423233 |
| ANXA2 | annexin A2 | -0.0422089 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0421803 |
| ZNF292 | zinc finger protein 292 | -0.0421459 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0421002 |
| CENPF | centromere protein F, 350/400kDa | -0.0413608 |
| RPL35A | ribosomal protein L35a | -0.0412169 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0412126 |
| TUBB | tubulin, beta class I | -0.0409269 |
| LDHA | lactate dehydrogenase A | -0.0407521 |
| CANX | calnexin | -0.0406695 |
| CADM1 | cell adhesion molecule 1 | -0.0406285 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0394516 |
| RPS8 | ribosomal protein S8 | -0.0392611 |
| PLIN2 | perilipin 2 | -0.0389975 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0384206 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0384177 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0377515 |
| FRMD4A | FERM domain containing 4A | -0.0371102 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0369325 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0369068 |
| TMSB4X | thymosin beta 4, X-linked | -0.0367014 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0364461 |
| COL1A2 | collagen, type I, alpha 2 | -0.0363156 |
| ANLN | anillin, actin binding protein | -0.0362735 |
| RBM39 | RNA binding motif protein 39 | -0.0356795 |
| RPL11 | ribosomal protein L11 | -0.0346762 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0346669 |
| CTSD | cathepsin D | -0.0346135 |
| RRBP1 | ribosome binding protein 1 | -0.0341824 |
| RPL26 | ribosomal protein L26 | -0.0340511 |
| RTN4 | reticulon 4 | -0.0339701 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0339582 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0337536 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0335994 |
| MAP4 | microtubule-associated protein 4 | -0.0329816 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0325023 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.032459 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0319904 |
| ENO1 | enolase 1, (alpha) | -0.0319076 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0318332 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0316484 |
| DEK | DEK proto-oncogene | -0.0311208 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0307889 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0306929 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0306885 |
| CD63 | CD63 molecule | -0.030598 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0304241 |
| RPL37A | ribosomal protein L37a | -0.0303589 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0303527 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.030251 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0300538 |
| MKI67 | marker of proliferation Ki-67 | -0.0297119 |
| COL1A1 | collagen, type I, alpha 1 | -0.0294879 |
| HMGA1 | high mobility group AT-hook 1 | -0.029107 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0290515 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0290008 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0288399 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0286658 |
| RPLP2 | ribosomal protein, large, P2 | -0.0286365 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0285568 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0285132 |
| RAI1 | retinoic acid induced 1 | -0.0283976 |
