| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Relugolix perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Relugolix_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0940821 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0847583 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0651405 |
| ANXA1 | annexin A1 | 0.0528148 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0523682 |
| EGFR | epidermal growth factor receptor | 0.0520419 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0507881 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0498325 |
| SVIL | supervillin | 0.0497999 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.047187 |
| JMJD1C | jumonji domain containing 1C | 0.0452225 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0427176 |
| FNDC3B | fibronectin type III domain containing 3B | 0.03808 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0371528 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0358553 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0352865 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0345307 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0337262 |
| CALR | calreticulin | 0.0333709 |
| EGR1 | early growth response 1 | 0.0317501 |
| CLIC4 | chloride intracellular channel 4 | 0.0317249 |
| PKM | pyruvate kinase, muscle | 0.0305058 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0304715 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0303248 |
| FAM13A | family with sequence similarity 13, member A | 0.0299293 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0297177 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0287861 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0283894 |
| ITGB4 | integrin, beta 4 | 0.0275434 |
| CAPRIN2 | caprin family member 2 | 0.0268505 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0266428 |
| CEP295 | centrosomal protein 295kDa | 0.0265034 |
| GPC5 | glypican 5 | 0.0264247 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0258722 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0258188 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0258008 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0256374 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0246349 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0246117 |
| HBP1 | HMG-box transcription factor 1 | 0.0244569 |
| SKIL | SKI-like proto-oncogene | 0.024379 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0243743 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0242571 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0241882 |
| RAI1 | retinoic acid induced 1 | 0.0239273 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0238406 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0236421 |
| DMXL1 | Dmx-like 1 | 0.0236377 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0236073 |
| MYOF | myoferlin | 0.0235957 |
| INSIG1 | insulin induced gene 1 | 0.0235322 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0234567 |
| ANXA5 | annexin A5 | 0.0232387 |
| COG5 | component of oligomeric golgi complex 5 | 0.023191 |
| PDE10A | phosphodiesterase 10A | 0.0231392 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0230448 |
| FTL | ferritin, light polypeptide | 0.0229812 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0229188 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0227855 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0227488 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0227109 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0226944 |
| YAF2 | YY1 associated factor 2 | 0.0225456 |
| ANXA2 | annexin A2 | 0.0224923 |
| MB21D2 | Mab-21 domain containing 2 | 0.0224903 |
| CEP290 | centrosomal protein 290kDa | 0.0224723 |
| SERF2 | small EDRK-rich factor 2 | 0.022449 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0223723 |
| FAM3C | family with sequence similarity 3, member C | 0.0223661 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0217207 |
| SEC24A | SEC24 family member A | 0.0214941 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.021244 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.0211509 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0211376 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0211078 |
| CYTH1 | cytohesin 1 | 0.0210984 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0210832 |
| OPTN | optineurin | 0.0209298 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0209253 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0209182 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0207025 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0206289 |
| RANBP2 | RAN binding protein 2 | 0.0206112 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.0205536 |
| NGLY1 | N-glycanase 1 | 0.0204627 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0204349 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.020392 |
| ZDBF2 | zinc finger, DBF-type containing 2 | 0.0203393 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0202883 |
| ETF1 | eukaryotic translation termination factor 1 | 0.0201793 |
| APP | amyloid beta (A4) precursor protein | 0.0198391 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.019799 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0196194 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0195951 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0195943 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0194278 |
| BSG | basigin (Ok blood group) | 0.0194028 |
| ITGAV | integrin, alpha V | 0.019261 |
| HELZ | helicase with zinc finger | 0.0190454 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0189684 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.106969 |
| PTMA | prothymosin, alpha | -0.100786 |
| SMYD3 | SET and MYND domain containing 3 | -0.098586 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0957844 |
| RBM39 | RNA binding motif protein 39 | -0.0896713 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0786856 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0778029 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0773221 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0752285 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0729681 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0720458 |
| TMSB10 | thymosin beta 10 | -0.0714313 |
| CENPF | centromere protein F, 350/400kDa | -0.068437 |
| CD44 | CD44 molecule (Indian blood group) | -0.0660424 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0637381 |
| GOLGA4 | golgin A4 | -0.0614019 |
| MATR3 | matrin 3 | -0.0587165 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0561741 |
| RDX | radixin | -0.0559178 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0558501 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0540398 |
| SPAG9 | sperm associated antigen 9 | -0.0536684 |
| TPX2 | TPX2, microtubule-associated | -0.0535537 |
| ATM | ATM serine/threonine kinase | -0.0531147 |
| LMO7 | LIM domain 7 | -0.0527785 |
| GNAS | GNAS complex locus | -0.0500661 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0483903 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0470175 |
| YBX3 | Y box binding protein 3 | -0.0464106 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0461062 |
| KIAA1328 | KIAA1328 | -0.0459167 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0456645 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0456564 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0455413 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0451415 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0450655 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0449503 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0422819 |
| AK1 | adenylate kinase 1 | -0.0416607 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0416427 |
| SDC4 | syndecan 4 | -0.0415008 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.040855 |
| DNER | delta/notch-like EGF repeat containing | -0.0407954 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.040676 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0405817 |
| NALCN | sodium leak channel, non selective | -0.0403305 |
| IGF2 | insulin-like growth factor 2 | -0.0402265 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0402261 |
| PRSS23 | protease, serine, 23 | -0.0402043 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0395064 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0386099 |
| RSF1 | remodeling and spacing factor 1 | -0.0385443 |
| NAV2 | neuron navigator 2 | -0.0384014 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0382626 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0377484 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0376525 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0375627 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0374842 |
| BBX | bobby sox homolog (Drosophila) | -0.0374309 |
| OGA | O-GlcNAcase | -0.0373661 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0373085 |
| ANLN | anillin, actin binding protein | -0.0370753 |
| H3-3B | H3.3 histone B | -0.0369375 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0368786 |
| KIF5B | kinesin family member 5B | -0.0366633 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0360555 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0352565 |
| CCDC91 | coiled-coil domain containing 91 | -0.0350777 |
| RPL35A | ribosomal protein L35a | -0.0347823 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.034776 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0347323 |
| RRBP1 | ribosome binding protein 1 | -0.0341527 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0338413 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0332612 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0331868 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0328248 |
| CPNE1 | copine I | -0.0328176 |
| CENPP | centromere protein P | -0.0326771 |
| CEP170 | centrosomal protein 170kDa | -0.0324577 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0321989 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0321339 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0319328 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0318478 |
| DEK | DEK proto-oncogene | -0.0316036 |
| RAB10 | RAB10, member RAS oncogene family | -0.0315235 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0313715 |
| ATXN1 | ataxin 1 | -0.0312765 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0312192 |
| ZNF644 | zinc finger protein 644 | -0.0310637 |
| CEP57 | centrosomal protein 57kDa | -0.0301492 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0300988 |
| RASA2 | RAS p21 protein activator 2 | -0.0300498 |
| OSMR | oncostatin M receptor | -0.0299324 |
| RB1 | retinoblastoma 1 | -0.0297718 |
| RPS13 | ribosomal protein S13 | -0.0296487 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0295166 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0294964 |
| HJURP | Holliday junction recognition protein | -0.0294797 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0294623 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0294577 |
