| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Relugolix perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Relugolix_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0756254 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0708237 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0686029 |
| FAM13A | family with sequence similarity 13, member A | 0.0577058 |
| NDRG1 | N-myc downstream regulated 1 | 0.0445867 |
| VEGFA | vascular endothelial growth factor A | 0.0433509 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.033745 |
| ANXA5 | annexin A5 | 0.0318601 |
| MYOF | myoferlin | 0.0293041 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0282582 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243866 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0235469 |
| ENO1 | enolase 1, (alpha) | 0.0232814 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0215244 |
| TPM3 | tropomyosin 3 | 0.0207855 |
| PRELID2 | PRELI domain containing 2 | 0.0207385 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0203115 |
| CD109 | CD109 molecule | 0.0200684 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0188386 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0184901 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0179739 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0176971 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0162639 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0158643 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0154732 |
| PTK2 | protein tyrosine kinase 2 | 0.0154107 |
| RYBP | RING1 and YY1 binding protein | 0.0153748 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0147698 |
| ARRDC3 | arrestin domain containing 3 | 0.0146482 |
| RIOK3 | RIO kinase 3 | 0.0146235 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0144885 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0143969 |
| STC2 | stanniocalcin 2 | 0.0143419 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0142198 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0139184 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0138417 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0136528 |
| FAT1 | FAT atypical cadherin 1 | 0.0136348 |
| STC1 | stanniocalcin 1 | 0.0131114 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0130059 |
| RNF145 | ring finger protein 145 | 0.0129401 |
| FLNB | filamin B, beta | 0.0128863 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0126306 |
| FOSL1 | FOS-like antigen 1 | 0.012448 |
| IGF2 | insulin-like growth factor 2 | 0.0124251 |
| XPO1 | exportin 1 | 0.0123959 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.011967 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.011849 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.011727 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0116824 |
| USP12 | ubiquitin specific peptidase 12 | 0.011591 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0113501 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0113441 |
| RAD51B | RAD51 paralog B | 0.0111153 |
| NBAS | neuroblastoma amplified sequence | 0.0111047 |
| ASPH | aspartate beta-hydroxylase | 0.0110046 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0109858 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0109643 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0107338 |
| TPD52 | tumor protein D52 | 0.0106972 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0106905 |
| CRLS1 | cardiolipin synthase 1 | 0.010359 |
| LYST | lysosomal trafficking regulator | 0.0101198 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.00999659 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00998392 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00995218 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.00983636 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00981906 |
| ZNF148 | zinc finger protein 148 | 0.00980599 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00956656 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00955327 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.00949237 |
| NGLY1 | N-glycanase 1 | 0.00946875 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.00944243 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00943244 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.00941152 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00940299 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.00918825 |
| MYO1B | myosin IB | 0.0091659 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00915587 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00912761 |
| E2F7 | E2F transcription factor 7 | 0.0091174 |
| FBXO32 | F-box protein 32 | 0.00910379 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.00907459 |
| YAP1 | Yes-associated protein 1 | 0.00906435 |
| CEP250 | centrosomal protein 250kDa | 0.00903575 |
| FHIT | fragile histidine triad | 0.00903261 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0090163 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00901262 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0090075 |
| SPICE1 | spindle and centriole associated protein 1 | 0.00900674 |
| LAMC2 | laminin, gamma 2 | 0.00897052 |
| RIC1 | RAB6A GEF complex partner 1 | 0.00893779 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00891302 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.00890569 |
| CDK19 | cyclin-dependent kinase 19 | 0.00888533 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00888138 |
| RAB18 | RAB18, member RAS oncogene family | 0.00883334 |
| ANXA1 | annexin A1 | 0.00876387 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.00875991 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.392442 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.230568 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.222513 |
| NRG1 | neuregulin 1 | -0.12824 |
| SQSTM1 | sequestosome 1 | -0.119338 |
| EXT1 | exostosin glycosyltransferase 1 | -0.11142 |
| PTMA | prothymosin, alpha | -0.109159 |
| TMSB10 | thymosin beta 10 | -0.0897494 |
| VCL | vinculin | -0.0886009 |
| FTL | ferritin, light polypeptide | -0.0813193 |
| GLIS3 | GLIS family zinc finger 3 | -0.0784576 |
| HMGA2 | high mobility group AT-hook 2 | -0.0770679 |
| FN1 | fibronectin 1 | -0.0741348 |
| SYT1 | synaptotagmin I | -0.0697043 |
| RPS6 | ribosomal protein S6 | -0.0657991 |
| OSMR | oncostatin M receptor | -0.0654218 |
| NTN4 | netrin 4 | -0.0618752 |
| CANX | calnexin | -0.060922 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0578624 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0569609 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0538814 |
| MT2A | metallothionein 2A | -0.052721 |
| HLA-B | major histocompatibility complex, class I, B | -0.0522587 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0503106 |
| TMEM156 | transmembrane protein 156 | -0.0485478 |
| ITGA1 | integrin, alpha 1 | -0.0474712 |
| NRP1 | neuropilin 1 | -0.046098 |
| S100A6 | S100 calcium binding protein A6 | -0.0447787 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0444128 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0435158 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.043262 |
| RPL35A | ribosomal protein L35a | -0.0430054 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0423561 |
| VIM | vimentin | -0.0412402 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0412168 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0405854 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0401661 |
| RPL31 | ribosomal protein L31 | -0.0399356 |
| PALLD | palladin, cytoskeletal associated protein | -0.0397413 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0390237 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0388184 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0385512 |
| KSR1 | kinase suppressor of ras 1 | -0.0383181 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0373002 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0372866 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0360115 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353041 |
| VMP1 | vacuole membrane protein 1 | -0.0351361 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0349664 |
| RAB31 | RAB31, member RAS oncogene family | -0.0342138 |
| EFNA5 | ephrin-A5 | -0.0340531 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0333306 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0330836 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0329245 |
| FOXP1 | forkhead box P1 | -0.0327115 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.032287 |
| AEBP2 | AE binding protein 2 | -0.0322672 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0321591 |
| AOPEP | aminopeptidase O (putative) | -0.0321 |
| SEPTIN9 | septin 9 | -0.0319676 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0318407 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0315015 |
| ETV1 | ets variant 1 | -0.0313834 |
| NCOA7 | nuclear receptor coactivator 7 | -0.031278 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0310446 |
| NXN | nucleoredoxin | -0.03096 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0308488 |
| BPTF | bromodomain PHD finger transcription factor | -0.0296961 |
| HDLBP | high density lipoprotein binding protein | -0.0296874 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0292624 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0291861 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0286608 |
| RPL37 | ribosomal protein L37 | -0.0284708 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0283561 |
| TNS3 | tensin 3 | -0.0282897 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0282244 |
| RPS27 | ribosomal protein S27 | -0.0282159 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0281046 |
| JMJD1C | jumonji domain containing 1C | -0.0278906 |
| RPL19 | ribosomal protein L19 | -0.0278089 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0273136 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0272091 |
| RPS16 | ribosomal protein S16 | -0.0271795 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0269955 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.026987 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0268621 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0268601 |
| SMOX | spermine oxidase | -0.0268344 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0268211 |
| KLHL5 | kelch-like family member 5 | -0.0267694 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266828 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0266111 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0263184 |
| RPL34 | ribosomal protein L34 | -0.0262905 |
| RPS24 | ribosomal protein S24 | -0.0257608 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0256943 |
| RAB10 | RAB10, member RAS oncogene family | -0.0255239 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0255189 |
| SSH1 | slingshot protein phosphatase 1 | -0.0254747 |
| SMIM14 | small integral membrane protein 14 | -0.0254588 |
