Renal Interstitial Fibrosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0235989
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Genes

119 genes associated with the disease Renal Interstitial Fibrosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADORA2A adenosine A2a receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR2 angiotensin II receptor, type 2
AIF1 allograft inflammatory factor 1
ANGPT4 angiopoietin 4
APLN apelin
ARRB1 arrestin, beta 1
ATG5 autophagy related 5
BCL2 B-cell CLL/lymphoma 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
C3 complement component 3
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD68 CD68 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLEC11A C-type lectin domain family 11, member A
COMMD3-BMI1 COMMD3-BMI1 readthrough
CRISP2 cysteine-rich secretory protein 2
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
DDR2 discoidin domain receptor tyrosine kinase 2
DNAH8 dynein, axonemal, heavy chain 8
EGR1 early growth response 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELP2 elongator acetyltransferase complex subunit 2
EPHB2 EPH receptor B2
EPO erythropoietin
F2R coagulation factor II (thrombin) receptor
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FFAR4 free fatty acid receptor 4
FGF23 fibroblast growth factor 23
FHL2 four and a half LIM domains 2
FN1 fibronectin 1
FST follistatin
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDNF glial cell derived neurotrophic factor
GPNMB glycoprotein (transmembrane) nmb
GSTA3 glutathione S-transferase alpha 3
HAVCR1 hepatitis A virus cellular receptor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNF1B HNF1 homeobox B
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL33 interleukin 33
IL6 interleukin 6
ILK integrin-linked kinase
KL klotho
KRT1 keratin 1, type II
LAYN layilin
LEFTY1 left-right determination factor 1
LGMN legumain
LRP2 low density lipoprotein receptor-related protein 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MT1B metallothionein 1B
MTTP microsomal triglyceride transfer protein
MYD88 myeloid differentiation primary response 88
MYO1C myosin IC
NFE2L2 nuclear factor, erythroid 2-like 2
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH1 notch 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRK Nik related kinase
PDGFA platelet-derived growth factor alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKM pyruvate kinase, muscle
PLAT plasminogen activator, tissue
PLG plasminogen
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPID peptidylprolyl isomerase D
PPIF peptidylprolyl isomerase F
PRSS55 protease, serine, 55
PTEN phosphatase and tensin homolog
RGCC regulator of cell cycle
RHOF ras homolog family member F (in filopodia)
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SOAT1 sterol O-acyltransferase 1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SPP1 secreted phosphoprotein 1
SPZ1 spermatogenic leucine zipper 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX1 T-box 1
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TPSD1 tryptase delta 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TXN thioredoxin
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin