| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/65981 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Repaglinide relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF274 | zinc finger protein 274 | 1.27 |
| COL17A1 | collagen, type XVII, alpha 1 | 1.24 |
| DUOX1 | dual oxidase 1 | 0.97 |
| BCOR | BCL6 corepressor | 0.97 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.94 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | 0.84 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C | 0.7 |
| USP27X | ubiquitin specific peptidase 27, X-linked | 0.63 |
| GLMP | glycosylated lysosomal membrane protein | 0.57 |
| SLC16A6 | solute carrier family 16, member 6 | 0.55 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.51 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.51 |
| AKNA | AT-hook transcription factor | 0.51 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.5 |
| SLC39A3 | solute carrier family 39 (zinc transporter), member 3 | 0.49 |
| ZNF205 | zinc finger protein 205 | 0.49 |
| SFXN4 | sideroflexin 4 | 0.48 |
| TNNC2 | troponin C type 2 (fast) | 0.48 |
| FAM241A | family with sequence similarity 241 member A | 0.48 |
| TRAIP | TRAF interacting protein | 0.47 |
| NMU | neuromedin U | 0.46 |
| MYBPC2 | myosin binding protein C, fast type | 0.45 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 0.45 |
| COL1A1 | collagen, type I, alpha 1 | 0.45 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.43 |
| MROH6 | maestro heat-like repeat family member 6 | 0.42 |
| DUS2 | dihydrouridine synthase 2 | 0.42 |
| NEMP2 | nuclear envelope integral membrane protein 2 | 0.42 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | 0.41 |
| RPS21 | ribosomal protein S21 | 0.41 |
| CENPK | centromere protein K | 0.4 |
| GPSM2 | G-protein signaling modulator 2 | 0.39 |
| FRMPD3 | FERM and PDZ domain containing 3 | 0.39 |
| ATXN7L3B | ataxin 7-like 3B | 0.38 |
| UPP1 | uridine phosphorylase 1 | 0.38 |
| C2ORF42 | chromosome 2 open reading frame 42 | 0.37 |
| RWDD1 | RWD domain containing 1 | 0.37 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.37 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.36 |
| C2CD2L | C2CD2-like | 0.36 |
| SET | SET nuclear proto-oncogene | 0.36 |
| HOXA10 | homeobox A10 | 0.36 |
| PRMT2IP | PRMT2 interacting protein | 0.36 |
| AZIN1 | antizyme inhibitor 1 | 0.36 |
| ZNRD1 | zinc ribbon domain containing 1 | 0.35 |
| BMP8A | bone morphogenetic protein 8a | 0.35 |
| GXYLT1 | glucoside xylosyltransferase 1 | 0.35 |
| TOX2 | TOX high mobility group box family member 2 | 0.34 |
| RAP1GAP | RAP1 GTPase activating protein | 0.34 |
| DENND5A | DENN/MADD domain containing 5A | 0.34 |
| NOP10 | NOP10 ribonucleoprotein | 0.33 |
| RNF115 | ring finger protein 115 | 0.33 |
| TREX1 | three prime repair exonuclease 1 | 0.33 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.33 |
| ZNF362 | zinc finger protein 362 | 0.33 |
| RPL36A | ribosomal protein L36a | 0.32 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.32 |
| CCDC102A | coiled-coil domain containing 102A | 0.32 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.31 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 0.31 |
| BBS10 | Bardet-Biedl syndrome 10 | 0.31 |
| ZNF22 | zinc finger protein 22 | 0.31 |
| GJC1 | gap junction protein, gamma 1, 45kDa | 0.3 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.3 |
| CENPP | centromere protein P | 0.3 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | 0.3 |
| MT2A | metallothionein 2A | 0.3 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.29 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.29 |
| ARL6IP6 | ADP-ribosylation factor-like 6 interacting protein 6 | 0.29 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.29 |
| BAG4 | BCL2-associated athanogene 4 | 0.29 |
| TRIM39 | tripartite motif containing 39 | 0.28 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.28 |
| MT1F | metallothionein 1F | 0.28 |
| LYRM7 | LYR motif containing 7 | 0.28 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.28 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.28 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.28 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.27 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.27 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.27 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 0.27 |
| RAB6D | RAB6D, member RAS oncogene family | 0.27 |
| CCNYL1 | cyclin Y-like 1 | 0.27 |
| PTPRU | protein tyrosine phosphatase, receptor type, U | 0.27 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.27 |
| MID2 | midline 2 | 0.27 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.27 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | 0.26 |
| HMGB3 | high mobility group box 3 | 0.26 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 | 0.26 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.26 |
| HCFC2 | host cell factor C2 | 0.26 |
| ATL1 | atlastin GTPase 1 | 0.26 |
| C6ORF136 | chromosome 6 open reading frame 136 | 0.25 |
| ACY1 | aminoacylase 1 | 0.25 |
| ANKRD46 | ankyrin repeat domain 46 | 0.25 |
| ACTBL2 | actin, beta-like 2 | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZG16B | zymogen granule protein 16B | -2.74 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -1.5 |
| GRHL1 | grainyhead-like 1 (Drosophila) | -1.12 |
| PIP | prolactin-induced protein | -1.06 |
| ANKRD36 | ankyrin repeat domain 36 | -0.62 |
| EPHA4 | EPH receptor A4 | -0.58 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.55 |
| SPPL2B | signal peptide peptidase like 2B | -0.54 |
| ZNF567 | zinc finger protein 567 | -0.53 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -0.51 |
| FBXO17 | F-box protein 17 | -0.5 |
| LIPH | lipase, member H | -0.49 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.49 |
| FTL | ferritin, light polypeptide | -0.47 |
| ABHD3 | abhydrolase domain containing 3 | -0.47 |
| FAM120C | family with sequence similarity 120C | -0.46 |
| TMEM59 | transmembrane protein 59 | -0.46 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | -0.45 |
| C2CD4C | C2 calcium-dependent domain containing 4C | -0.45 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | -0.45 |
| SLC66A2 | solute carrier family 66 member 2 | -0.45 |
| FAM219A | family with sequence similarity 219, member A | -0.44 |
| KIAA0513 | KIAA0513 | -0.44 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.43 |
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | -0.43 |
| CHN1 | chimerin 1 | -0.43 |
| MYLK | myosin light chain kinase | -0.42 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.41 |
| MPZL2 | myelin protein zero-like 2 | -0.4 |
| RPL26 | ribosomal protein L26 | -0.39 |
| ABHD17C | abhydrolase domain containing 17C | -0.39 |
| MAGEA6 | melanoma antigen family A6 | -0.39 |
| IRF9 | interferon regulatory factor 9 | -0.37 |
| TMEM208 | transmembrane protein 208 | -0.37 |
| FAM241B | family with sequence similarity 241 member B | -0.37 |
| MISP3 | MISP family member 3 | -0.37 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 | -0.36 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | -0.36 |
| PLCB4 | phospholipase C, beta 4 | -0.36 |
| NOTCH3 | notch 3 | -0.36 |
| PLIN2 | perilipin 2 | -0.36 |
| TRIM62 | tripartite motif containing 62 | -0.36 |
| ZBTB12 | zinc finger and BTB domain containing 12 | -0.35 |
| ZNF92 | zinc finger protein 92 | -0.35 |
| MSANTD4 | Myb/SANT-like DNA-binding domain containing 4 with coiled-coils | -0.35 |
| RPGR | retinitis pigmentosa GTPase regulator | -0.35 |
| CPTP | ceramide-1-phosphate transfer protein | -0.35 |
| CEBPZOS | CEBPZ opposite strand | -0.35 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | -0.34 |
| FABP6 | fatty acid binding protein 6, ileal | -0.33 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.33 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.33 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | -0.33 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.33 |
| TMC6 | transmembrane channel-like 6 | -0.33 |
| PXDN | peroxidasin | -0.33 |
| HPCAL4 | hippocalcin like 4 | -0.33 |
| TSPAN33 | tetraspanin 33 | -0.33 |
| CYTH3 | cytohesin 3 | -0.32 |
| FAT3 | FAT atypical cadherin 3 | -0.32 |
| MYOM3 | myomesin 3 | -0.32 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | -0.32 |
| CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1 | -0.32 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.32 |
| ABITRAM | actin binding transcription modulator | -0.32 |
| HMOX1 | heme oxygenase 1 | -0.32 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.31 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.31 |
| VWA5B2 | von Willebrand factor A domain containing 5B2 | -0.31 |
| SON | SON DNA binding protein | -0.31 |
| DOCK4 | dedicator of cytokinesis 4 | -0.31 |
| ATOX1 | antioxidant 1 copper chaperone | -0.31 |
| MKRN3 | makorin ring finger protein 3 | -0.3 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.3 |
| KLHDC8B | kelch domain containing 8B | -0.29 |
| WDR20 | WD repeat domain 20 | -0.29 |
| ISL2 | ISL LIM homeobox 2 | -0.29 |
| BPTF | bromodomain PHD finger transcription factor | -0.29 |
| ZNF319 | zinc finger protein 319 | -0.29 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 | -0.29 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -0.29 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.29 |
| FN1 | fibronectin 1 | -0.29 |
| UBAP1 | ubiquitin associated protein 1 | -0.29 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.29 |
| ZNF691 | zinc finger protein 691 | -0.28 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.28 |
| C7ORF25 | chromosome 7 open reading frame 25 | -0.28 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.28 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | -0.28 |
| LYRM1 | LYR motif containing 1 | -0.28 |
| SHROOM3 | shroom family member 3 | -0.28 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase | -0.28 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin | -0.28 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.28 |
| RNF220 | ring finger protein 220 | -0.27 |
| IRX4 | iroquois homeobox 4 | -0.27 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.27 |
| MAP2 | microtubule-associated protein 2 | -0.27 |
| DOLPP1 | dolichyldiphosphatase 1 | -0.27 |
