Reperfusion Injury Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0035126
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Genes

299 genes associated with the disease Reperfusion Injury in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRL1 adhesion G protein-coupled receptor L1
ADGRL3 adhesion G protein-coupled receptor L3
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR2 angiotensin II receptor, type 2
AIF1 allograft inflammatory factor 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
ALOX12 arachidonate 12-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA5 annexin A5
AOC3 amine oxidase, copper containing 3
APAF1 apoptotic peptidase activating factor 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOM apolipoprotein M
AQP4 aquaporin 4
ARG1 arginase 1
ATF3 activating transcription factor 3
BAD BCL2-associated agonist of cell death
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BMP6 bone morphogenetic protein 6
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BSG basigin (Ok blood group)
BTG2 BTG family, member 2
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5 complement component 5
C5AR1 complement component 5a receptor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAST calpastatin
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCNG1 cyclin G1
CD2AP CD2-associated protein
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFH complement factor H
CHAT choline O-acetyltransferase
CLDN4 claudin 4
CNR1 cannabinoid receptor 1 (brain)
CSPG4 chondroitin sulfate proteoglycan 4
CTSB cathepsin B
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DCC DCC netrin 1 receptor
DSG1 desmoglein 1
EDN1 endothelin 1
EDN2 endothelin 2
EDNRB endothelin receptor type B
EEF2 eukaryotic translation elongation factor 2
EFNA5 ephrin-A5
EFNB2 ephrin-B2
EGF epidermal growth factor
EGR1 early growth response 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ENO2 enolase 2 (gamma, neuronal)
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
EPO erythropoietin
ERCC1 excision repair cross-complementation group 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
FAS Fas cell surface death receptor
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGF7 fibroblast growth factor 7
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
G6PD glucose-6-phosphate dehydrogenase
GAST gastrin
GHRL ghrelin/obestatin prepropeptide
GJB1 gap junction protein, beta 1, 32kDa
GLUD1 glutamate dehydrogenase 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSR glutathione reductase
HBEGF heparin-binding EGF-like growth factor
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HRH3 histamine receptor H3
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IL10 interleukin 10
IL12A interleukin 12A
IL13 interleukin 13
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRF1 interferon regulatory factor 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUN jun proto-oncogene
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KLK1 kallikrein 1
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LEP leptin
LIG3 ligase III, DNA, ATP-dependent
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP2 microtubule-associated protein 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPK9 mitogen-activated protein kinase 9
MET MET proto-oncogene, receptor tyrosine kinase
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MT-ATP6 ATP synthase F0 subunit 6
MT-ATP8 ATP synthase F0 subunit 8
MT-CYB cytochrome b
MUC1 mucin 1, cell surface associated
MYD88 myeloid differentiation primary response 88
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NES nestin
NFE2L2 nuclear factor, erythroid 2-like 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
OGA O-GlcNAcase
OPRM1 opioid receptor, mu 1
OTC ornithine carbamoyltransferase
OXT oxytocin/neurophysin I prepropeptide
PARP1 poly (ADP-ribose) polymerase 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE5A phosphodiesterase 5A, cGMP-specific
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKLR pyruvate kinase, liver and RBC
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLD2 phospholipase D2
POLB polymerase (DNA directed), beta
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRSS1 protease, serine, 1 (trypsin 1)
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100B S100 calcium binding protein B
SAT1 spermidine/spermine N1-acetyltransferase 1
SCFD1 sec1 family domain containing 1
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFTPC surfactant protein C
SI sucrase-isomaltase (alpha-glucosidase)
SIRT7 sirtuin 7
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLK STE20-like kinase
SLPI secretory leukocyte peptidase inhibitor
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STC1 stanniocalcin 1
STC2 stanniocalcin 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TBXAS1 thromboxane A synthase 1 (platelet)
TERT telomerase reverse transcriptase
TFAM transcription factor A, mitochondrial
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TICAM1 toll-like receptor adaptor molecule 1
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TXN thioredoxin
TXN2 thioredoxin 2
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
VCAM1 vascular cell adhesion molecule 1
VEGFC vascular endothelial growth factor C
VIM vimentin
WNT3A wingless-type MMTV integration site family, member 3A
XDH xanthine dehydrogenase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF354A zinc finger protein 354A