Replisome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. (Gene Ontology, GO_0030894)
External Link http://amigo.geneontology.org/amigo/term/GO:0030894
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Genes

15 proteins localized to the Replisome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
POLR1A polymerase (RNA) I polypeptide A, 194kDa 5.0
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 5.0
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 5.0
POLR1B polymerase (RNA) I polypeptide B, 128kDa 5.0
POLD2 polymerase (DNA directed), delta 2, accessory subunit 5.0
RPA3 replication protein A3, 14kDa 5.0
RPA4 replication protein A4, 30kDa 5.0
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 5.0
PRIM2 primase, DNA, polypeptide 2 (58kDa) 5.0
PRIM1 primase, DNA, polypeptide 1 (49kDa) 5.0
DONSON downstream neighbor of SON 5.0
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 5.0
PCNA proliferating cell nuclear antigen 4.0
MCM3 minichromosome maintenance complex component 3 4.0
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.0