Resolution of D-loop Structures through Holliday Junction Intermediates Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5693568
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Genes

35 proteins participating in the Resolution of D-loop Structures through Holliday Junction Intermediates pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ATM ATM serine/threonine kinase
BARD1 BRCA1 associated RING domain 1
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
DNA2 DNA replication helicase/nuclease 2
EME1 essential meiotic structure-specific endonuclease 1
EME2 essential meiotic structure-specific endonuclease subunit 2
EXO1 exonuclease 1
FIGNL1 fidgetin-like 1
FIRRM FIGNL1 interacting regulator of recombination and mitosis
GEN1 GEN1 Holliday junction 5' flap endonuclease
KAT5 K(lysine) acetyltransferase 5
MRE11 MRE11 homolog, double strand break repair nuclease
MUS81 MUS81 structure-specific endonuclease subunit
NBN nibrin
PALB2 partner and localizer of BRCA2
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD51B RAD51 paralog B
RAD51C RAD51 paralog C
RAD51D RAD51 paralog D
RBBP8 retinoblastoma binding protein 8
RMI1 RecQ mediated genome instability 1
RMI2 RecQ mediated genome instability 2
SEM1 SEM1 26S proteasome subunit
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
SLX4 SLX4 structure-specific endonuclease subunit
SPIDR scaffolding protein involved in DNA repair
TOP3A topoisomerase (DNA) III alpha
WRN Werner syndrome, RecQ helicase-like
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3