Resveratrol_A-172 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in A-172 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.218153
AKAP12 A kinase (PRKA) anchor protein 12 0.199893
TRIO trio Rho guanine nucleotide exchange factor 0.136636
AHNAK AHNAK nucleoprotein 0.0979413
NAV2 neuron navigator 2 0.0954311
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0839616
LOXL2 lysyl oxidase-like 2 0.0751787
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0747589
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0704666
SLC39A11 solute carrier family 39, member 11 0.069728
PBX3 pre-B-cell leukemia homeobox 3 0.0641233
SQSTM1 sequestosome 1 0.0621934
COL5A2 collagen, type V, alpha 2 0.060283
FLNB filamin B, beta 0.0594182
ELL2 elongation factor, RNA polymerase II, 2 0.0591346
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0574129
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0562614
APP amyloid beta (A4) precursor protein 0.0544115
NDRG1 N-myc downstream regulated 1 0.0543444
RHOBTB3 Rho-related BTB domain containing 3 0.0511573
MYH9 myosin, heavy chain 9, non-muscle 0.0500021
BHLHE40 basic helix-loop-helix family, member e40 0.0475539
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.0474393
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0469447
RND3 Rho family GTPase 3 0.0457828
ZEB1 zinc finger E-box binding homeobox 1 0.0454066
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.0443496
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0436338
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0434659
MYOF myoferlin 0.0427183
OGA O-GlcNAcase 0.0414719
TMSB4X thymosin beta 4, X-linked 0.0399645
MSI2 musashi RNA-binding protein 2 0.0393543
AHNAK2 AHNAK nucleoprotein 2 0.0387833
SBF2 SET binding factor 2 0.0387827
CCND1 cyclin D1 0.0385235
BACE2 beta-site APP-cleaving enzyme 2 0.0368207
ZNF292 zinc finger protein 292 0.0367494
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.0364592
MMP12 matrix metallopeptidase 12 0.0359796
VIM vimentin 0.0357327
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.035331
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0352651
UBC ubiquitin C 0.0342044
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0335644
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0331936
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0330551
ESYT2 extended synaptotagmin-like protein 2 0.0326802
AUTS2 autism susceptibility candidate 2 0.0325163
RNMT RNA (guanine-7-) methyltransferase 0.032454
CD109 CD109 molecule 0.0320898
COL4A2 collagen, type IV, alpha 2 0.0314654
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0313573
CENPF centromere protein F, 350/400kDa 0.0306918
TNIP1 TNFAIP3 interacting protein 1 0.0305501
ARFGEF3 ARFGEF family member 3 0.0300829
RUNX1 runt-related transcription factor 1 0.0299562
TM4SF19 transmembrane 4 L six family member 19 0.0298841
FAM107B family with sequence similarity 107, member B 0.0295558
SEPTIN9 septin 9 0.029263
NAV1 neuron navigator 1 0.029254
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0289054
SP3 Sp3 transcription factor 0.0288772
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0286419
PLEC plectin 0.0286275
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.0283915
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.0283039
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.0281023
STK10 serine/threonine kinase 10 0.0278446
MXI1 MAX interactor 1, dimerization protein 0.0274542
TAC4 tachykinin 4 (hemokinin) 0.0272198
CSTB cystatin B (stefin B) 0.026719
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0263513
CTSB cathepsin B 0.0261087
FNIP1 folliculin interacting protein 1 0.0260812
IQGAP1 IQ motif containing GTPase activating protein 1 0.0260039
ANO6 anoctamin 6 0.0259721
MIMS1 mitochondrial inner membrane scaffold 1 0.0257032
XPO1 exportin 1 0.0255686
MACF1 microtubule-actin crosslinking factor 1 0.0255521
CD99 CD99 molecule 0.0255086
DSPP dentin sialophosphoprotein 0.0254975
PDIA3 protein disulfide isomerase family A, member 3 0.0254841
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0253005
TRAM2 translocation associated membrane protein 2 0.025248
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0251885
COL3A1 collagen, type III, alpha 1 0.0246803
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0246414
PFKP phosphofructokinase, platelet 0.024579
AVL9 AVL9 homolog (S. cerevisiase) 0.0245243
DST dystonin 0.0244769
YEATS2 YEATS domain containing 2 0.0243875
RNF213 ring finger protein 213 0.0241843
ZMIZ1 zinc finger, MIZ-type containing 1 0.0241402
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0239976
TPM4 tropomyosin 4 0.0239434
NFE2L1 nuclear factor, erythroid 2-like 1 0.0237904
RTN4 reticulon 4 0.0236415
RIOK3 RIO kinase 3 0.0230015
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0227687

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.202921
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.143347
IGFBP3 insulin-like growth factor binding protein 3 -0.110804
MAP1B microtubule-associated protein 1B -0.0864659
COL8A1 collagen, type VIII, alpha 1 -0.0815603
PLAT plasminogen activator, tissue -0.0699634
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0567176
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -0.054572
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0529067
B2M beta-2-microglobulin -0.0520997
SUCNR1 succinate receptor 1 -0.0461534
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.0433799
VCL vinculin -0.0431085
POTEF POTE ankyrin domain family, member F -0.0385639
IFI6 interferon, alpha-inducible protein 6 -0.038444
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0381317
PRSS23 protease, serine, 23 -0.0375104
COL5A1 collagen, type V, alpha 1 -0.0370514
LOX lysyl oxidase -0.0331696
SAMD9 sterile alpha motif domain containing 9 -0.0326293
TUBB4B tubulin, beta 4B class IVb -0.0324244
PODXL podocalyxin-like -0.0290445
GLIS3 GLIS family zinc finger 3 -0.0287448
LRRC17 leucine rich repeat containing 17 -0.0274594
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0242896
PDE4D phosphodiesterase 4D, cAMP-specific -0.0242862
FN1 fibronectin 1 -0.0240952
MAP4 microtubule-associated protein 4 -0.0233062
KIFAP3 kinesin-associated protein 3 -0.0232227
SLC38A2 solute carrier family 38, member 2 -0.0231505
S100A4 S100 calcium binding protein A4 -0.022944
INTS6 integrator complex subunit 6 -0.0228921
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0227807
S100A11 S100 calcium binding protein A11 -0.0225335
MBNL1 muscleblind-like splicing regulator 1 -0.0225083
SEC61G Sec61 gamma subunit -0.0221263
PCDH7 protocadherin 7 -0.021216
RIGI RNA sensor RIG-I -0.0206349
PFN1 profilin 1 -0.0202288
ALCAM activated leukocyte cell adhesion molecule -0.0202063
WWTR1 WW domain containing transcription regulator 1 -0.02017
SH3KBP1 SH3-domain kinase binding protein 1 -0.0197401
SRSF11 serine/arginine-rich splicing factor 11 -0.0195792
MEIS2 Meis homeobox 2 -0.0191502
VEGFC vascular endothelial growth factor C -0.0190788
HLA-C major histocompatibility complex, class I, C -0.0189262
SYT1 synaptotagmin I -0.0189201
RASAL2 RAS protein activator like 2 -0.0185095
IL7R interleukin 7 receptor -0.0184988
FBXO11 F-box protein 11 -0.0180664
FNDC3A fibronectin type III domain containing 3A -0.0179532
CKAP4 cytoskeleton-associated protein 4 -0.0179259
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0175709
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0173005
TLE4 transducin-like enhancer of split 4 -0.0172793
ARL15 ADP-ribosylation factor-like 15 -0.0170661
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0168735
EHBP1 EH domain binding protein 1 -0.0167863
PRRC2C proline-rich coiled-coil 2C -0.01664
IARS1 isoleucyl-tRNA synthetase 1 -0.0165581
CD44 CD44 molecule (Indian blood group) -0.0165118
ENO2 enolase 2 (gamma, neuronal) -0.0163854
ANKUB1 ankyrin repeat and ubiquitin domain containing 1 -0.0162283
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0161716
LHFPL6 LHFPL tetraspan subfamily member 6 -0.0160858
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0159909
PRRX1 paired related homeobox 1 -0.0159266
OASL 2'-5'-oligoadenylate synthetase-like -0.0156599
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0152669
EIF5B eukaryotic translation initiation factor 5B -0.0151611
SERF2 small EDRK-rich factor 2 -0.0147429
GDI1 GDP dissociation inhibitor 1 -0.014699
TPST1 tyrosylprotein sulfotransferase 1 -0.0145794
C6ORF62 chromosome 6 open reading frame 62 -0.0145635
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0144823
JAZF1 JAZF zinc finger 1 -0.0144389
TUBA1B tubulin, alpha 1b -0.0143911
IFI27 interferon, alpha-inducible protein 27 -0.0143494
EXT1 exostosin glycosyltransferase 1 -0.0142775
HSPB1 heat shock 27kDa protein 1 -0.0142731
GNAS GNAS complex locus -0.0141943
GDI2 GDP dissociation inhibitor 2 -0.0141362
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -0.013951
NRP1 neuropilin 1 -0.0138337
TUBA1C tubulin, alpha 1c -0.0137657
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough -0.0136662
TAGLN2 transgelin 2 -0.0136164
GLS2 glutaminase 2 (liver, mitochondrial) -0.0136036
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0135665
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.013485
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.0134829
TET3 tet methylcytosine dioxygenase 3 -0.0134724
PTGES2 prostaglandin E synthase 2 -0.0134444
RAB7A RAB7A, member RAS oncogene family -0.0133776
SMC4 structural maintenance of chromosomes 4 -0.0132808
IPO9 importin 9 -0.0132615
TAOK3 TAO kinase 3 -0.0132598
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.0132218
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.0131653
PKM pyruvate kinase, muscle -0.0131131