Resveratrol_A-427 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in A-427 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
BIRC3 baculoviral IAP repeat containing 3 0.0848111
ZBTB20 zinc finger and BTB domain containing 20 0.0740755
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0724019
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0650679
NCEH1 neutral cholesterol ester hydrolase 1 0.0633372
TXNRD1 thioredoxin reductase 1 0.060524
VMP1 vacuole membrane protein 1 0.0566471
KIF5B kinesin family member 5B 0.0554358
KDM3A lysine (K)-specific demethylase 3A 0.0542092
NIPBL Nipped-B homolog (Drosophila) 0.0502296
CPOX coproporphyrinogen oxidase 0.0486444
XPO1 exportin 1 0.0483827
NEK7 NIMA-related kinase 7 0.047706
EEF2 eukaryotic translation elongation factor 2 0.047672
FBXL20 F-box and leucine-rich repeat protein 20 0.0456839
KLHL24 kelch-like family member 24 0.0451707
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0450395
CXADR coxsackie virus and adenovirus receptor 0.0447176
BCAS3 breast carcinoma amplified sequence 3 0.0428653
BIRC6 baculoviral IAP repeat containing 6 0.042248
OGA O-GlcNAcase 0.0418465
PRKCI protein kinase C, iota 0.0409542
MED13L mediator complex subunit 13-like 0.0405156
EXOC6B exocyst complex component 6B 0.0398669
RB1CC1 RB1-inducible coiled-coil 1 0.0395942
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.038816
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0377677
VIM vimentin 0.0376283
CEP192 centrosomal protein 192kDa 0.0369938
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0357628
NCOR1 nuclear receptor corepressor 1 0.035744
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0355347
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.035024
EIF4A2 eukaryotic translation initiation factor 4A2 0.0346088
TMEM123 transmembrane protein 123 0.0338479
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0334795
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0331538
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0330432
MATR3 matrin 3 0.0328819
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.0328573
IL6ST interleukin 6 signal transducer 0.0325787
NCOA1 nuclear receptor coactivator 1 0.0322161
SPAG9 sperm associated antigen 9 0.0321682
PCM1 pericentriolar material 1 0.0320397
ADAM17 ADAM metallopeptidase domain 17 0.0315047
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0314746
SQSTM1 sequestosome 1 0.0312957
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0312888
MBNL1 muscleblind-like splicing regulator 1 0.0311338
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.030928
THOC1 THO complex 1 0.0307039
PPP4R1 protein phosphatase 4, regulatory subunit 1 0.0304394
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0304388
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0302615
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0297771
LMO7 LIM domain 7 0.0286481
ZFR zinc finger RNA binding protein 0.0286118
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0286022
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.028369
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0281197
TAOK1 TAO kinase 1 0.0279613
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0277795
AKAP9 A kinase (PRKA) anchor protein 9 0.0277747
COG5 component of oligomeric golgi complex 5 0.0274827
CDK19 cyclin-dependent kinase 19 0.0274778
OXR1 oxidation resistance 1 0.0273878
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0268632
BBX bobby sox homolog (Drosophila) 0.026805
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0266385
CEP95 centrosomal protein 95kDa 0.0265775
EIF1 eukaryotic translation initiation factor 1 0.0265426
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.026541
CNOT2 CCR4-NOT transcription complex, subunit 2 0.026517
MON2 MON2 homolog (S. cerevisiae) 0.0265096
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.026251
KIF1B kinesin family member 1B 0.0261336
SBF2 SET binding factor 2 0.0259718
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0259498
FBXO11 F-box protein 11 0.0258979
PHIP pleckstrin homology domain interacting protein 0.0256947
EIF4B eukaryotic translation initiation factor 4B 0.025583
CKAP5 cytoskeleton associated protein 5 0.0255776
ECT2 epithelial cell transforming 2 0.0254773
CHD1 chromodomain helicase DNA binding protein 1 0.0254297
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0254293
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0253372
LMAN1 lectin, mannose-binding, 1 0.0252984
HLTF helicase-like transcription factor 0.0250787
TNPO1 transportin 1 0.0249839
PUM2 pumilio RNA-binding family member 2 0.0244732
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0243742
STAG2 stromal antigen 2 0.0243484
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0241208
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0239504
USP15 ubiquitin specific peptidase 15 0.0239018
EPS15 epidermal growth factor receptor pathway substrate 15 0.0238972
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0236879
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.0236365
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0235948
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.0234792

decreased expression

Symbol Name Standardized Value
NLGN1 neuroligin 1 -0.181455
TMSB10 thymosin beta 10 -0.176784
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.144597
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.131621
HMGA2 high mobility group AT-hook 2 -0.0977855
EHBP1 EH domain binding protein 1 -0.0953553
PDE4D phosphodiesterase 4D, cAMP-specific -0.0909038
RPL35A ribosomal protein L35a -0.0861799
RPS12 ribosomal protein S12 -0.0851089
RAB7A RAB7A, member RAS oncogene family -0.0737692
RPL37A ribosomal protein L37a -0.0734218
EGR1 early growth response 1 -0.0732654
ASPH aspartate beta-hydroxylase -0.0725257
PTMA prothymosin, alpha -0.0644661
LRRTM4 leucine rich repeat transmembrane neuronal 4 -0.0626627
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -0.0588511
ZNF804A zinc finger protein 804A -0.0563918
PCDH7 protocadherin 7 -0.0527329
TAS2R14 taste receptor, type 2, member 14 -0.0520907
TPI1 triosephosphate isomerase 1 -0.0519184
ACTG1 actin gamma 1 -0.0510861
FTL ferritin, light polypeptide -0.0479699
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0476961
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0475653
TUBA1B tubulin, alpha 1b -0.0469844
TPT1 tumor protein, translationally-controlled 1 -0.0469759
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0460712
NEBL nebulette -0.0454149
BCHE butyrylcholinesterase -0.045021
NHSL1 NHS-like 1 -0.0445894
ADIPOR2 adiponectin receptor 2 -0.0432026
ENO1 enolase 1, (alpha) -0.0425722
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0418554
NAP1L1 nucleosome assembly protein 1-like 1 -0.0417897
YAP1 Yes-associated protein 1 -0.0412108
SLC38A2 solute carrier family 38, member 2 -0.0411168
EDARADD EDAR-associated death domain -0.0409028
RPL9 ribosomal protein L9 -0.0385073
RRM2 ribonucleotide reductase M2 -0.0379272
RPL12 ribosomal protein L12 -0.037647
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0367889
CSMD3 CUB and Sushi multiple domains 3 -0.0365819
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0361572
PRDX1 peroxiredoxin 1 -0.0358185
INTS6 integrator complex subunit 6 -0.0357715
MYL12B myosin, light chain 12B, regulatory -0.0350182
DTNA dystrobrevin, alpha -0.0349198
CALR calreticulin -0.0346789
BABAM2 BRISC and BRCA1 A complex member 2 -0.0346773
GCG glucagon -0.0338188
TUBA1C tubulin, alpha 1c -0.0335959
NABP1 nucleic acid binding protein 1 -0.0331722
SMC4 structural maintenance of chromosomes 4 -0.0330559
RPS3 ribosomal protein S3 -0.0319558
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0313966
VDAC1 voltage-dependent anion channel 1 -0.0312908
DDIT3 DNA-damage-inducible transcript 3 -0.0312094
CMIP c-Maf inducing protein -0.0310874
MTAP methylthioadenosine phosphorylase -0.0310204
RPL31 ribosomal protein L31 -0.0300609
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0296286
MSRB3 methionine sulfoxide reductase B3 -0.0292153
LRRC23 leucine rich repeat containing 23 -0.0290663
XPOT exportin, tRNA -0.0289503
P3H2 prolyl 3-hydroxylase 2 -0.0288194
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.028633
NR5A2 nuclear receptor subfamily 5, group A, member 2 -0.0279572
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0277601
HSPE1 heat shock 10kDa protein 1 -0.0275523
CUBN cubilin (intrinsic factor-cobalamin receptor) -0.0274581
HDAC9 histone deacetylase 9 -0.0274075
RPL36 ribosomal protein L36 -0.0267447
LDHA lactate dehydrogenase A -0.0261717
RPS27A ribosomal protein S27a -0.0261154
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0260069
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0256914
RPS19 ribosomal protein S19 -0.0255696
PGK1 phosphoglycerate kinase 1 -0.0253622
RPS8 ribosomal protein S8 -0.025294
COMMD10 COMM domain containing 10 -0.0252758
FADS2 fatty acid desaturase 2 -0.0250798
NAV3 neuron navigator 3 -0.025079
RPS14 ribosomal protein S14 -0.025071
RPL37 ribosomal protein L37 -0.0249619
RPS25 ribosomal protein S25 -0.0248871
RPS29 ribosomal protein S29 -0.0244474
KDM4C lysine (K)-specific demethylase 4C -0.0243813
TRA2B transformer 2 beta homolog (Drosophila) -0.0241617
CUX1 cut-like homeobox 1 -0.0239953
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0238797
RPS17 ribosomal protein S17 -0.0238756
NUP98 nucleoporin 98kDa -0.0237129
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0235092
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0234203
UNC13A unc-13 homolog A (C. elegans) -0.0234057
COL5A2 collagen, type V, alpha 2 -0.0234023
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0233316
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0231062
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0226285
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0224554