Resveratrol_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in CHP-212 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EXT1 exostosin glycosyltransferase 1 0.111089
TRIO trio Rho guanine nucleotide exchange factor 0.103699
LSAMP limbic system-associated membrane protein 0.0953809
CEMIP cell migration inducing protein, hyaluronan binding 0.0883018
FRMD4A FERM domain containing 4A 0.0635742
PCBP2 poly(rC) binding protein 2 0.0622445
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.0614817
NALF1 NALCN channel auxiliary factor 1 0.0595785
FNDC3B fibronectin type III domain containing 3B 0.0587542
PRKCA protein kinase C, alpha 0.0572598
ANTXR1 anthrax toxin receptor 1 0.0534078
VCL vinculin 0.0487853
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0484632
GPC5 glypican 5 0.0484125
CRH corticotropin releasing hormone 0.0473124
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0458378
AUTS2 autism susceptibility candidate 2 0.0444986
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.0439183
MBD5 methyl-CpG binding domain protein 5 0.043653
ZBTB20 zinc finger and BTB domain containing 20 0.0426995
SSBP3 single stranded DNA binding protein 3 0.0415568
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0412541
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0400239
ADARB1 adenosine deaminase, RNA-specific, B1 0.0375967
IGF1R insulin-like growth factor 1 receptor 0.037169
LINGO2 leucine rich repeat and Ig domain containing 2 0.0368724
COL4A5 collagen, type IV, alpha 5 0.0366954
KDM4C lysine (K)-specific demethylase 4C 0.0365811
TIMP3 TIMP metallopeptidase inhibitor 3 0.0362877
NRG1 neuregulin 1 0.0356443
GMDS GDP-mannose 4,6-dehydratase 0.0350547
PTPRM protein tyrosine phosphatase, receptor type, M 0.0349907
PTEN phosphatase and tensin homolog 0.0347623
CSNK1A1 casein kinase 1, alpha 1 0.0347041
PLPP1 phospholipid phosphatase 1 0.0346217
TBC1D22A TBC1 domain family, member 22A 0.0344537
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0344455
DNM3 dynamin 3 0.0341034
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0336436
BCAS3 breast carcinoma amplified sequence 3 0.0334212
PBX1 pre-B-cell leukemia homeobox 1 0.0327857
MEIS2 Meis homeobox 2 0.0324273
DACH2 dachshund family transcription factor 2 0.0319654
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0316231
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0316096
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0315648
GLCCI1 glucocorticoid induced 1 0.0315371
AOPEP aminopeptidase O (putative) 0.0312285
PRKG1 protein kinase, cGMP-dependent, type I 0.0312132
GLS2 glutaminase 2 (liver, mitochondrial) 0.03101
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0309393
SAMD4A sterile alpha motif domain containing 4A 0.0309044
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0305113
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0304603
KCNT2 potassium channel, sodium activated subfamily T, member 2 0.030345
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0302629
SBF2 SET binding factor 2 0.0301823
CHD9 chromodomain helicase DNA binding protein 9 0.0301632
ACBD6 acyl-CoA binding domain containing 6 0.0300109
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.0297353
AK1 adenylate kinase 1 0.0296436
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.0295726
CLTC clathrin, heavy chain (Hc) 0.0291216
PTPRE protein tyrosine phosphatase, receptor type, E 0.0290584
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0288605
TBC1D5 TBC1 domain family, member 5 0.028661
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0286538
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0284826
PHF3 PHD finger protein 3 0.0283001
RABGAP1L RAB GTPase activating protein 1-like 0.0281437
PSD3 pleckstrin and Sec7 domain containing 3 0.0278141
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0276158
TRPS1 trichorhinophalangeal syndrome I 0.0275505
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0272492
CEMIP2 cell migration inducing hyaluronidase 2 0.0271299
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0269341
USP34 ubiquitin specific peptidase 34 0.0268826
SENP6 SUMO1/sentrin specific peptidase 6 0.0267408
FNDC3A fibronectin type III domain containing 3A 0.0265953
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0265591
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0265378
TIMP2 TIMP metallopeptidase inhibitor 2 0.0263967
CANX calnexin 0.0263056
PDE4D phosphodiesterase 4D, cAMP-specific 0.0262527
METTL15 methyltransferase like 15 0.0260653
CDH10 cadherin 10, type 2 (T2-cadherin) 0.0258286
SDK1 sidekick cell adhesion molecule 1 0.0257543
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0256445
EIF4B eukaryotic translation initiation factor 4B 0.0256195
WDFY3 WD repeat and FYVE domain containing 3 0.0255524
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.0253961
FHIT fragile histidine triad 0.0253769
ARHGAP9 Rho GTPase activating protein 9 0.0252042
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0251707
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.0251477
RBM33 RNA binding motif protein 33 0.0249716
CADM1 cell adhesion molecule 1 0.0247061
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0246929
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0245633
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.0245351

decreased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 -0.32386
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.213167
PTMA prothymosin, alpha -0.10486
COL1A1 collagen, type I, alpha 1 -0.0838183
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0789155
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0744519
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0725196
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0708119
VIM vimentin -0.0675586
RPS6 ribosomal protein S6 -0.0639231
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0636382
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.0608583
H3-3B H3.3 histone B -0.0533502
RPL35A ribosomal protein L35a -0.052984
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0506671
RPLP1 ribosomal protein, large, P1 -0.0476938
RPL23 ribosomal protein L23 -0.0462142
RPL34 ribosomal protein L34 -0.0433253
RPS24 ribosomal protein S24 -0.0423274
NME2 NME/NM23 nucleoside diphosphate kinase 2 -0.0411354
CCNI cyclin I -0.040634
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0390823
GCC2 GRIP and coiled-coil domain containing 2 -0.0389335
B2M beta-2-microglobulin -0.0387815
FTL ferritin, light polypeptide -0.0387448
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0383947
CD36 CD36 molecule (thrombospondin receptor) -0.0379506
GNAS GNAS complex locus -0.0377233
TMSB10 thymosin beta 10 -0.0376054
ACTG1 actin gamma 1 -0.0373427
TPT1 tumor protein, translationally-controlled 1 -0.0367916
FMN1 formin 1 -0.0367841
PRRC2C proline-rich coiled-coil 2C -0.0361047
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0359031
RPLP0 ribosomal protein, large, P0 -0.0358496
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0357936
EIF1 eukaryotic translation initiation factor 1 -0.035126
TRIB2 tribbles pseudokinase 2 -0.0338955
TBX2 T-box 2 -0.0334308
CSNK1G1 casein kinase 1, gamma 1 -0.031712
RPS19 ribosomal protein S19 -0.0316132
CALD1 caldesmon 1 -0.0312968
SCG2 secretogranin II -0.0292867
RPL7A ribosomal protein L7a -0.0288401
TLE4 transducin-like enhancer of split 4 -0.028421
RPL19 ribosomal protein L19 -0.0283695
RAB7A RAB7A, member RAS oncogene family -0.0280023
RPL27 ribosomal protein L27 -0.0276855
RPL26 ribosomal protein L26 -0.027296
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0272202
CADM2 cell adhesion molecule 2 -0.0267316
RPL36A ribosomal protein L36a -0.0266071
NAP1L1 nucleosome assembly protein 1-like 1 -0.0265214
ITGA1 integrin, alpha 1 -0.0262409
RPL32 ribosomal protein L32 -0.0262095
RPL37A ribosomal protein L37a -0.0261547
TRA2A transformer 2 alpha homolog (Drosophila) -0.026145
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0260039
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -0.025761
SOX9 SRY (sex determining region Y)-box 9 -0.0256222
PNISR PNN-interacting serine/arginine-rich protein -0.0251638
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0250821
RPL8 ribosomal protein L8 -0.0245189
RACK1 receptor for activated C kinase 1 -0.0244801
HMGB2 high mobility group box 2 -0.0243179
RPL38 ribosomal protein L38 -0.0239721
RPS4X ribosomal protein S4, X-linked -0.0239555
RNF145 ring finger protein 145 -0.0238869
CHD4 chromodomain helicase DNA binding protein 4 -0.0235179
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0234912
IFI6 interferon, alpha-inducible protein 6 -0.0232925
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0232671
WDR45B WD repeat domain 45B -0.0229356
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0226783
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0224973
DCAF7 DDB1 and CUL4 associated factor 7 -0.022397
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0221719
LOC102724023 ES1 protein homolog, mitochondrial -0.021944
RPS3 ribosomal protein S3 -0.021716
DDIT4 DNA-damage-inducible transcript 4 -0.0214656
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0214226
ANXA2 annexin A2 -0.0213012
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.0212148
CENPF centromere protein F, 350/400kDa -0.0211974
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0207619
SUCO SUN domain containing ossification factor -0.0206831
MX2 MX dynamin-like GTPase 2 -0.0204191
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0202769
RPL9 ribosomal protein L9 -0.0202515
RLF rearranged L-myc fusion -0.0202485
HAND2 heart and neural crest derivatives expressed 2 -0.0199395
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0197135
TOX thymocyte selection-associated high mobility group box -0.0196996
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0195891
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.0195641
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0195359
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0194543
HMGB1 high mobility group box 1 -0.0194408
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.0193872
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0193865