Resveratrol_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in COLO 205 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SYNE2 spectrin repeat containing, nuclear envelope 2 0.101212
LMO7 LIM domain 7 0.0734483
PHF3 PHD finger protein 3 0.0725204
N4BP2L2 NEDD4 binding protein 2-like 2 0.0692216
TMC5 transmembrane channel-like 5 0.0663342
TSC22D1 TSC22 domain family, member 1 0.0491287
NCKAP5 NCK-associated protein 5 0.0477417
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0464713
IGFBP3 insulin-like growth factor binding protein 3 0.0452773
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0386745
PLSCR1 phospholipid scramblase 1 0.0381896
STS steroid sulfatase (microsomal), isozyme S 0.0351311
PDZD8 PDZ domain containing 8 0.0348873
SAMD4A sterile alpha motif domain containing 4A 0.0331914
KIF16B kinesin family member 16B 0.0329278
STK24 serine/threonine kinase 24 0.0310447
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0305071
SPATA13 spermatogenesis associated 13 0.0296223
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.0293169
ZBTB20 zinc finger and BTB domain containing 20 0.0285668
MBNL2 muscleblind-like splicing regulator 2 0.0275917
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0275913
ZMYND8 zinc finger, MYND-type containing 8 0.027492
BICRAL BICRA like chromatin remodeling complex associated protein 0.0274248
IGF1R insulin-like growth factor 1 receptor 0.0271804
CEMIP2 cell migration inducing hyaluronidase 2 0.0262606
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0255731
ZNF292 zinc finger protein 292 0.0253725
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.025243
ATP11A ATPase, class VI, type 11A 0.0251756
ERBIN erbb2 interacting protein 0.0250979
AFF1 AF4/FMR2 family, member 1 0.024674
IFNGR1 interferon gamma receptor 1 0.0238852
KLHL24 kelch-like family member 24 0.0238697
DISC1 disrupted in schizophrenia 1 0.0235903
IL20RA interleukin 20 receptor, alpha 0.0232145
MX1 MX dynamin-like GTPase 1 0.0230491
PARP9 poly (ADP-ribose) polymerase family, member 9 0.0226923
OARD1 O-acyl-ADP-ribose deacylase 1 0.0226093
OCLN occludin 0.0226007
KDM4C lysine (K)-specific demethylase 4C 0.0222681
MAML2 mastermind-like 2 (Drosophila) 0.0219975
BACE2 beta-site APP-cleaving enzyme 2 0.0219325
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.021895
EZR ezrin 0.0218045
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.0214088
EXOC4 exocyst complex component 4 0.0207502
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0206766
MCU mitochondrial calcium uniporter 0.0206203
USP54 ubiquitin specific peptidase 54 0.0205787
ANXA11 annexin A11 0.020191
ALPK1 alpha-kinase 1 0.0200708
KIF13B kinesin family member 13B 0.0194223
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0193073
RAD51B RAD51 paralog B 0.0192471
VMP1 vacuole membrane protein 1 0.0190431
MAP2K6 mitogen-activated protein kinase kinase 6 0.0189116
PCED1B PC-esterase domain containing 1B 0.0188867
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0188832
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.0186121
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0185456
MAP7 microtubule-associated protein 7 0.0185439
MLPH melanophilin 0.0183358
STK39 serine threonine kinase 39 0.0181671
PHACTR4 phosphatase and actin regulator 4 0.0181494
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0180502
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.0179226
AEBP2 AE binding protein 2 0.0179195
JAK1 Janus kinase 1 0.0174209
GOSR2 golgi SNAP receptor complex member 2 0.0173189
EFNA5 ephrin-A5 0.0169567
TGFBR3 transforming growth factor, beta receptor III 0.0169484
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.016945
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.0168928
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0168217
RAB22A RAB22A, member RAS oncogene family 0.0167214
FAAH2 fatty acid amide hydrolase 2 0.0166821
DNAH5 dynein, axonemal, heavy chain 5 0.0166511
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.01657
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.0164377
PTBP3 polypyrimidine tract binding protein 3 0.0163505
SPATA6L spermatogenesis associated 6-like 0.0162632
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0162145
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0161104
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0159785
MAN2A1 mannosidase, alpha, class 2A, member 1 0.0159134
DSCAM Down syndrome cell adhesion molecule 0.0159081
CYSTM1 cysteine-rich transmembrane module containing 1 0.0157958
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0157642
SLC22A23 solute carrier family 22, member 23 0.0157265
AOPEP aminopeptidase O (putative) 0.0156015
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0155602
FAT1 FAT atypical cadherin 1 0.0155497
MON2 MON2 homolog (S. cerevisiae) 0.0154962
EHBP1 EH domain binding protein 1 0.015482
TBCK TBC1 domain containing kinase 0.0153545
ARL15 ADP-ribosylation factor-like 15 0.0153216
NEBL nebulette 0.015181
AKAP11 A kinase (PRKA) anchor protein 11 0.0150897
MBD5 methyl-CpG binding domain protein 5 0.0150849

decreased expression

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.201998
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.198385
TPT1 tumor protein, translationally-controlled 1 -0.184017
PTMA prothymosin, alpha -0.155734
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.140602
B2M beta-2-microglobulin -0.0949919
LCN2 lipocalin 2 -0.0824478
FTL ferritin, light polypeptide -0.0806307
HLA-B major histocompatibility complex, class I, B -0.0760005
TMSB10 thymosin beta 10 -0.0753
RPS6 ribosomal protein S6 -0.0745286
RPL35A ribosomal protein L35a -0.0734335
VCL vinculin -0.0720744
INTS6 integrator complex subunit 6 -0.0624284
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0615706
MT2A metallothionein 2A -0.058491
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.057634
AREG amphiregulin -0.0573591
CALR calreticulin -0.0556836
RPL34 ribosomal protein L34 -0.0545696
RPL23 ribosomal protein L23 -0.054013
IFI6 interferon, alpha-inducible protein 6 -0.053054
PDIA3 protein disulfide isomerase family A, member 3 -0.052665
RPS24 ribosomal protein S24 -0.0519718
IFI27 interferon, alpha-inducible protein 27 -0.0503982
WSB1 WD repeat and SOCS box containing 1 -0.0491476
NDRG1 N-myc downstream regulated 1 -0.0487961
GMDS GDP-mannose 4,6-dehydratase -0.0469736
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0464827
RPL19 ribosomal protein L19 -0.0462225
RPL11 ribosomal protein L11 -0.0457424
HLA-C major histocompatibility complex, class I, C -0.0439503
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0438375
RUNX1 runt-related transcription factor 1 -0.0426282
RBM39 RNA binding motif protein 39 -0.0423712
PRRC2C proline-rich coiled-coil 2C -0.0423527
ACTG1 actin gamma 1 -0.0423352
RRBP1 ribosome binding protein 1 -0.0419419
RNF213 ring finger protein 213 -0.0419188
PDIA4 protein disulfide isomerase family A, member 4 -0.0418678
H1-0 H1.0 linker histone -0.0414907
RPS19 ribosomal protein S19 -0.0410552
RPS8 ribosomal protein S8 -0.0406926
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0405649
ENO1 enolase 1, (alpha) -0.0405255
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0396735
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0391597
RPL37A ribosomal protein L37a -0.03846
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0382656
HMGB1 high mobility group box 1 -0.0381977
ASPH aspartate beta-hydroxylase -0.0380802
RPLP1 ribosomal protein, large, P1 -0.0380543
RPL12 ribosomal protein L12 -0.0361261
MKI67 marker of proliferation Ki-67 -0.0354734
DIAPH3 diaphanous-related formin 3 -0.0352521
PKM pyruvate kinase, muscle -0.0347111
SLC38A1 solute carrier family 38, member 1 -0.0345374
SON SON DNA binding protein -0.0340009
S100A6 S100 calcium binding protein A6 -0.0338785
GNAS GNAS complex locus -0.033546
S100A9 S100 calcium binding protein A9 -0.033114
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0328741
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.032806
RPL26 ribosomal protein L26 -0.0327874
DSTN destrin (actin depolymerizing factor) -0.0323517
KRT19 keratin 19, type I -0.0323116
NCOR1 nuclear receptor corepressor 1 -0.0317652
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0315832
H3-3B H3.3 histone B -0.0313628
HLA-A major histocompatibility complex, class I, A -0.0313547
IER3 immediate early response 3 -0.0312676
KLF6 Kruppel-like factor 6 -0.0311392
GOLGA4 golgin A4 -0.0308168
RPS3 ribosomal protein S3 -0.0306462
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0305675
RPS11 ribosomal protein S11 -0.0304547
RSF1 remodeling and spacing factor 1 -0.0303687
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0300742
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0299003
C6ORF132 chromosome 6 open reading frame 132 -0.0298998
ANKRD11 ankyrin repeat domain 11 -0.029861
RPL31 ribosomal protein L31 -0.0297258
EFNB2 ephrin-B2 -0.0295554
TPI1 triosephosphate isomerase 1 -0.029411
VDAC1 voltage-dependent anion channel 1 -0.0293924
CANX calnexin -0.0293198
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0292343
S100A10 S100 calcium binding protein A10 -0.0291317
RPS27A ribosomal protein S27a -0.0291256
KDM3A lysine (K)-specific demethylase 3A -0.0290571
AGR2 anterior gradient 2 -0.0288381
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0288333
DLG1 discs, large homolog 1 (Drosophila) -0.0286441
VIM vimentin -0.0285637
EIF1 eukaryotic translation initiation factor 1 -0.0284116
TPM4 tropomyosin 4 -0.0283219
TRA2A transformer 2 alpha homolog (Drosophila) -0.0282456
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0280897
SMC4 structural maintenance of chromosomes 4 -0.0279274
DEK DEK proto-oncogene -0.0277677