Resveratrol_HS-578T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in HS-578T cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Resveratrol_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 0.387311
VEGFA vascular endothelial growth factor A 0.100597
COL6A3 collagen, type VI, alpha 3 0.0953467
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.0859584
TRIO trio Rho guanine nucleotide exchange factor 0.0784817
CDH13 cadherin 13 0.0780837
NAV2 neuron navigator 2 0.0739216
JARID2 jumonji, AT rich interactive domain 2 0.0712689
CXCL8 chemokine (C-X-C motif) ligand 8 0.0604694
EXT1 exostosin glycosyltransferase 1 0.0591431
DOCK5 dedicator of cytokinesis 5 0.0524132
ZBTB20 zinc finger and BTB domain containing 20 0.0523689
PDE10A phosphodiesterase 10A 0.049009
CADM1 cell adhesion molecule 1 0.0476348
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0423827
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0418984
LOXL2 lysyl oxidase-like 2 0.0405565
HIPK2 homeodomain interacting protein kinase 2 0.0376011
CLMP CXADR-like membrane protein 0.0361832
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0343972
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0343238
RND3 Rho family GTPase 3 0.0338168
ATP13A3 ATPase type 13A3 0.0321761
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0319008
GOLGA4 golgin A4 0.0316215
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0313059
FNIP1 folliculin interacting protein 1 0.0307728
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0307517
LPP LIM domain containing preferred translocation partner in lipoma 0.0302507
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0297528
PTK2 protein tyrosine kinase 2 0.0292688
YEATS2 YEATS domain containing 2 0.0292654
FMNL2 formin-like 2 0.0284118
PLEC plectin 0.0269404
GOLGB1 golgin B1 0.0264034
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0258818
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.024424
MRPS6 mitochondrial ribosomal protein S6 0.0243852
TMEM165 transmembrane protein 165 0.0237803
AKAP9 A kinase (PRKA) anchor protein 9 0.0233536
EGFR epidermal growth factor receptor 0.0232468
MLF1 myeloid leukemia factor 1 0.0221909
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0219285
CMIP c-Maf inducing protein 0.0217996
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0217547
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0216922
TTC3 tetratricopeptide repeat domain 3 0.0215277
EFNA5 ephrin-A5 0.021212
PSD3 pleckstrin and Sec7 domain containing 3 0.0210023
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0209848
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0208277
BTBD9 BTB (POZ) domain containing 9 0.0204717
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.0201296
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0199788
GJA1 gap junction protein, alpha 1, 43kDa 0.0195107
NAV1 neuron navigator 1 0.0194371
BACE2 beta-site APP-cleaving enzyme 2 0.0192803
ESYT2 extended synaptotagmin-like protein 2 0.0188714
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0186788
AHNAK AHNAK nucleoprotein 0.0186569
MACF1 microtubule-actin crosslinking factor 1 0.0186343
RLF rearranged L-myc fusion 0.0180976
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.018005
ZCCHC7 zinc finger, CCHC domain containing 7 0.0177541
FNDC3B fibronectin type III domain containing 3B 0.0172608
SHB Src homology 2 domain containing adaptor protein B 0.0172492
DPYD dihydropyrimidine dehydrogenase 0.0163321
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0162998
GRB10 growth factor receptor-bound protein 10 0.016223
MTSS1 metastasis suppressor 1 0.016209
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0161743
ZNF292 zinc finger protein 292 0.0161299
NALF1 NALCN channel auxiliary factor 1 0.0160311
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0157436
TPM4 tropomyosin 4 0.0157062
HMGA2 high mobility group AT-hook 2 0.0155976
FTH1 ferritin, heavy polypeptide 1 0.0154745
KDM4C lysine (K)-specific demethylase 4C 0.0154494
ERRFI1 ERBB receptor feedback inhibitor 1 0.0153496
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0152955
EMP1 epithelial membrane protein 1 0.0152925
ATXN1 ataxin 1 0.0149523
SYNJ2 synaptojanin 2 0.0148206
DLG1 discs, large homolog 1 (Drosophila) 0.0147896
CD109 CD109 molecule 0.01458
TRAM1 translocation associated membrane protein 1 0.0145791
EVI5 ecotropic viral integration site 5 0.0145704
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0145643
RUNX1 runt-related transcription factor 1 0.0144391
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0143969
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0143017
AMPD3 adenosine monophosphate deaminase 3 0.0142365
ARHGAP22 Rho GTPase activating protein 22 0.0141618
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0137612
ANXA1 annexin A1 0.0137475
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0137284
SBF2 SET binding factor 2 0.0137177
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.0136769
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0135274
HIPK3 homeodomain interacting protein kinase 3 0.0134828

decreased expression

Symbol Name Standardized Value
COL1A1 collagen, type I, alpha 1 -0.236344
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.204537
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.167586
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.146995
TMSB10 thymosin beta 10 -0.116664
VIM vimentin -0.104599
ENO1 enolase 1, (alpha) -0.0870789
FN1 fibronectin 1 -0.0800909
TIMP3 TIMP metallopeptidase inhibitor 3 -0.074362
UBC ubiquitin C -0.0717282
CALR calreticulin -0.0711512
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.070875
PTMA prothymosin, alpha -0.0660765
LDHA lactate dehydrogenase A -0.0598542
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0503167
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0502107
COL1A2 collagen, type I, alpha 2 -0.0491765
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0449527
CD44 CD44 molecule (Indian blood group) -0.0445241
ASPH aspartate beta-hydroxylase -0.0417421
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0403409
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0401138
CALU calumenin -0.0400024
PKM pyruvate kinase, muscle -0.0370589
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0360248
ALCAM activated leukocyte cell adhesion molecule -0.0345711
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0332346
CANX calnexin -0.0319187
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0305919
CALD1 caldesmon 1 -0.0302689
FTL ferritin, light polypeptide -0.0301662
RPS27A ribosomal protein S27a -0.0294596
SLC38A2 solute carrier family 38, member 2 -0.0275911
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0262527
CLIC4 chloride intracellular channel 4 -0.0254359
MAP1B microtubule-associated protein 1B -0.0239122
TPI1 triosephosphate isomerase 1 -0.0232934
VCL vinculin -0.0224312
PDE4D phosphodiesterase 4D, cAMP-specific -0.0223653
PDIA4 protein disulfide isomerase family A, member 4 -0.0216599
IL6ST interleukin 6 signal transducer -0.0213097
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0209479
PDLIM5 PDZ and LIM domain 5 -0.0207437
CAV1 caveolin 1, caveolae protein, 22kDa -0.0205413
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0202446
MT2A metallothionein 2A -0.0199586
POTEF POTE ankyrin domain family, member F -0.0199065
GARS1 glycyl-tRNA synthetase 1 -0.0197427
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0194687
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0188399
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0186985
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0183457
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0182371
B2M beta-2-microglobulin -0.0181151
PFN1 profilin 1 -0.017758
TM4SF1 transmembrane 4 L six family member 1 -0.0176842
TOP2A topoisomerase (DNA) II alpha 170kDa -0.017668
TUBA1B tubulin, alpha 1b -0.0174688
TMED9 transmembrane emp24 protein transport domain containing 9 -0.0174495
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0172322
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0169
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0168344
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0167723
S100A6 S100 calcium binding protein A6 -0.0166345
SRGN serglycin -0.0165864
POSTN periostin, osteoblast specific factor -0.0165063
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0164661
ICAM1 intercellular adhesion molecule 1 -0.016248
VDAC1 voltage-dependent anion channel 1 -0.0161735
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0159435
OAZ1 ornithine decarboxylase antizyme 1 -0.0159414
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.015858
SEC61G Sec61 gamma subunit -0.0158445
LMAN1 lectin, mannose-binding, 1 -0.0158073
PDIA3 protein disulfide isomerase family A, member 3 -0.0158026
YBX1 Y box binding protein 1 -0.0156736
TGFBI transforming growth factor, beta-induced, 68kDa -0.0154623
JAG1 jagged 1 -0.0153382
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0152502
LOX lysyl oxidase -0.0151751
NAP1L1 nucleosome assembly protein 1-like 1 -0.0148454
SAMD9 sterile alpha motif domain containing 9 -0.0145923
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0141224
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0140259
PDIA6 protein disulfide isomerase family A, member 6 -0.0139463
KDM3A lysine (K)-specific demethylase 3A -0.0138288
WSB1 WD repeat and SOCS box containing 1 -0.0137153
TPM1 tropomyosin 1 (alpha) -0.0137122
TPM2 tropomyosin 2 (beta) -0.0136464
GLIPR1 GLI pathogenesis-related 1 -0.0136415
ACTG1 actin gamma 1 -0.0136144
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0135241
CYB5R3 cytochrome b5 reductase 3 -0.0134897
MBNL1 muscleblind-like splicing regulator 1 -0.0134789
SPDYA speedy/RINGO cell cycle regulator family member A -0.0133828
PALLD palladin, cytoskeletal associated protein -0.0133217
RPS19 ribosomal protein S19 -0.0133198
CSF1 colony stimulating factor 1 (macrophage) -0.0133181
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.0133131
CST3 cystatin C -0.0133063