Resveratrol_HepG2/C3A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in HepG2/C3A cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Resveratrol_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.25554
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.146976
TNS1 tensin 1 0.09048
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0815199
TXNRD1 thioredoxin reductase 1 0.0655467
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.058617
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0549415
GPC6 glypican 6 0.0543536
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0537185
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0514454
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0505463
NDRG1 N-myc downstream regulated 1 0.0488007
SVIL supervillin 0.0478718
RPS12 ribosomal protein S12 0.0475193
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0455794
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0452581
RAI14 retinoic acid induced 14 0.0440311
DOCK5 dedicator of cytokinesis 5 0.0438401
SAMD4A sterile alpha motif domain containing 4A 0.0404235
RPL4 ribosomal protein L4 0.0394321
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0390579
ARHGAP21 Rho GTPase activating protein 21 0.0368919
GRB10 growth factor receptor-bound protein 10 0.0362762
MBNL2 muscleblind-like splicing regulator 2 0.0360767
GCLC glutamate-cysteine ligase, catalytic subunit 0.0359997
RPL3 ribosomal protein L3 0.035335
PEG3 paternally expressed 3 0.0352862
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0346775
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0343975
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0340071
ESYT2 extended synaptotagmin-like protein 2 0.0337221
FAM13A family with sequence similarity 13, member A 0.0337218
SYNE1 spectrin repeat containing, nuclear envelope 1 0.033523
EEF1G eukaryotic translation elongation factor 1 gamma 0.0334405
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.0334228
IGFBP3 insulin-like growth factor binding protein 3 0.032843
CRY1 cryptochrome circadian clock 1 0.0323998
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0312148
IGFBP1 insulin-like growth factor binding protein 1 0.0311722
EEF2 eukaryotic translation elongation factor 2 0.0303088
CEMIP2 cell migration inducing hyaluronidase 2 0.0301546
FTH1 ferritin, heavy polypeptide 1 0.0300593
ENO1 enolase 1, (alpha) 0.029956
PAWR PRKC, apoptosis, WT1, regulator 0.0296367
AHSG alpha-2-HS-glycoprotein 0.0294354
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0294055
DNAH5 dynein, axonemal, heavy chain 5 0.0291045
VEGFA vascular endothelial growth factor A 0.0288182
PCBP2 poly(rC) binding protein 2 0.0288113
MCL1 myeloid cell leukemia 1 0.0287795
ERRFI1 ERBB receptor feedback inhibitor 1 0.0280487
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0279823
STC2 stanniocalcin 2 0.0274673
RPS17 ribosomal protein S17 0.0274086
ARHGAP9 Rho GTPase activating protein 9 0.027359
DUSP6 dual specificity phosphatase 6 0.0271365
FOXP1 forkhead box P1 0.0270319
CCL20 chemokine (C-C motif) ligand 20 0.026909
DLC1 DLC1 Rho GTPase activating protein 0.026191
PLIN2 perilipin 2 0.0259657
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0258936
FAT1 FAT atypical cadherin 1 0.0257554
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0256629
FERMT1 fermitin family member 1 0.0255666
RUNX1 runt-related transcription factor 1 0.0253608
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.0253227
MBNL1 muscleblind-like splicing regulator 1 0.0252193
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0244674
EIF4B eukaryotic translation initiation factor 4B 0.024436
AAK1 AP2 associated kinase 1 0.0242301
NFE2L1 nuclear factor, erythroid 2-like 1 0.0239332
SLC35F5 solute carrier family 35, member F5 0.0232332
AKAP13 A kinase (PRKA) anchor protein 13 0.0230901
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0224854
DIAPH1 diaphanous-related formin 1 0.0223213
TF transferrin 0.0218918
SNX9 sorting nexin 9 0.0217928
ZNF638 zinc finger protein 638 0.0217001
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0216829
ATP10A ATPase, class V, type 10A 0.0216149
RPL37 ribosomal protein L37 0.021292
CD109 CD109 molecule 0.0210533
ARFGEF3 ARFGEF family member 3 0.0209374
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0209053
EFL1 elongation factor like GTPase 1 0.0208451
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0205304
ATF3 activating transcription factor 3 0.020152
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0201282
RB1CC1 RB1-inducible coiled-coil 1 0.0200026
TRIO trio Rho guanine nucleotide exchange factor 0.0199404
TCIM transcriptional and immune response regulator 0.0198717
SEC24A SEC24 family member A 0.0198587
OSBPL10 oxysterol binding protein-like 10 0.0196735
DTNA dystrobrevin, alpha 0.0196251
ITGA6 integrin, alpha 6 0.0195233
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.019426
WWC1 WW and C2 domain containing 1 0.019415
TCP11L2 t-complex 11, testis-specific-like 2 0.0193814
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0193296
PDIA3 protein disulfide isomerase family A, member 3 0.0192926

decreased expression

Symbol Name Standardized Value
APOB apolipoprotein B -0.274511
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.186981
IGF2 insulin-like growth factor 2 -0.149495
GPC3 glypican 3 -0.143669
APOA2 apolipoprotein A-II -0.133233
FN1 fibronectin 1 -0.0983117
TPT1 tumor protein, translationally-controlled 1 -0.0975818
TM4SF1 transmembrane 4 L six family member 1 -0.0911339
VCL vinculin -0.0835769
TRIM26 tripartite motif containing 26 -0.0801672
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0765142
MT2A metallothionein 2A -0.070292
RRBP1 ribosome binding protein 1 -0.0641971
RBM39 RNA binding motif protein 39 -0.0633571
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.063104
TMSB10 thymosin beta 10 -0.0620621
STAU1 staufen double-stranded RNA binding protein 1 -0.0606795
APOE apolipoprotein E -0.0586144
A2M alpha-2-macroglobulin -0.0580462
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0566958
EXT1 exostosin glycosyltransferase 1 -0.0556944
RPL11 ribosomal protein L11 -0.0533217
PDLIM5 PDZ and LIM domain 5 -0.0526226
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -0.0488271
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0483883
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -0.0483335
PTCHD4 patched domain containing 4 -0.0478257
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0472491
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -0.0472161
RPS24 ribosomal protein S24 -0.0459695
RPS21 ribosomal protein S21 -0.0451457
AMBP alpha-1-microglobulin/bikunin precursor -0.0442919
PTMA prothymosin, alpha -0.0438159
SLC38A2 solute carrier family 38, member 2 -0.042642
FBF1 Fas (TNFRSF6) binding factor 1 -0.042517
LRMDA leucine rich melanocyte differentiation associated -0.0419176
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0413043
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0399578
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.039735
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0390051
EML4 echinoderm microtubule associated protein like 4 -0.0385456
H1-0 H1.0 linker histone -0.0376491
LRRTM4 leucine rich repeat transmembrane neuronal 4 -0.0367357
INTS6 integrator complex subunit 6 -0.0366609
TMEM123 transmembrane protein 123 -0.0365619
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0355198
GNAS GNAS complex locus -0.0351
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0348459
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0347136
KDM3A lysine (K)-specific demethylase 3A -0.0346893
ACTG1 actin gamma 1 -0.0340864
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0330904
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0328826
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0322755
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.03164
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0313957
MIDN midnolin -0.0313946
KIF21A kinesin family member 21A -0.0312888
TM9SF3 transmembrane 9 superfamily member 3 -0.0312089
MYL12B myosin, light chain 12B, regulatory -0.0311117
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.031019
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0310116
FNDC3B fibronectin type III domain containing 3B -0.030782
NAP1L1 nucleosome assembly protein 1-like 1 -0.0307134
JUN jun proto-oncogene -0.0307017
MALT1 MALT1 paracaspase -0.0306793
UTRN utrophin -0.0305105
MBNL3 muscleblind-like splicing regulator 3 -0.0301552
IFI6 interferon, alpha-inducible protein 6 -0.0300928
NRIP1 nuclear receptor interacting protein 1 -0.0297191
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0296192
GLG1 golgi glycoprotein 1 -0.0290788
RNF213 ring finger protein 213 -0.0290233
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0289769
ZBTB20 zinc finger and BTB domain containing 20 -0.0286283
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0286021
NCOA7 nuclear receptor coactivator 7 -0.0282559
PTPRF protein tyrosine phosphatase, receptor type, F -0.0279385
ARID3A AT rich interactive domain 3A (BRIGHT-like) -0.0279122
CST3 cystatin C -0.0277461
NKD1 naked cuticle homolog 1 (Drosophila) -0.0276863
NIPBL Nipped-B homolog (Drosophila) -0.0276728
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.027652
RPLP2 ribosomal protein, large, P2 -0.0276092
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0275529
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0274964
PDGFB platelet-derived growth factor beta polypeptide -0.0273487
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0273041
EIF5B eukaryotic translation initiation factor 5B -0.0271734
ARHGAP18 Rho GTPase activating protein 18 -0.0265153
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0263027
MT1X metallothionein 1X -0.0262536
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0261814
UGP2 UDP-glucose pyrophosphorylase 2 -0.0257523
RPL34 ribosomal protein L34 -0.0253521
BIRC6 baculoviral IAP repeat containing 6 -0.0251657
ANKRD17 ankyrin repeat domain 17 -0.0250261
TRA2A transformer 2 alpha homolog (Drosophila) -0.0248515
IFIH1 interferon induced with helicase C domain 1 -0.0247683
PEG10 paternally expressed 10 -0.0247593