Resveratrol_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TIMP3 TIMP metallopeptidase inhibitor 3 0.235921
RAI14 retinoic acid induced 14 0.0918206
MEF2A myocyte enhancer factor 2A 0.0868497
MTSS1 metastasis suppressor 1 0.081598
PDE4D phosphodiesterase 4D, cAMP-specific 0.0801938
LMO7 LIM domain 7 0.0658275
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0601367
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0571474
NAV2 neuron navigator 2 0.051442
CEMIP cell migration inducing protein, hyaluronan binding 0.0510042
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0475407
SOD2 superoxide dismutase 2, mitochondrial 0.0430234
FTH1 ferritin, heavy polypeptide 1 0.0424166
PDLIM5 PDZ and LIM domain 5 0.0395498
PSD3 pleckstrin and Sec7 domain containing 3 0.0322011
ZC3H12C zinc finger CCCH-type containing 12C 0.030882
SULF1 sulfatase 1 0.0279182
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.027622
TGM2 transglutaminase 2 0.0273308
ZEB1 zinc finger E-box binding homeobox 1 0.0272821
ATP9A ATPase, class II, type 9A 0.026676
SQSTM1 sequestosome 1 0.0257367
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.0248727
TNS3 tensin 3 0.0247858
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.0245704
AHNAK AHNAK nucleoprotein 0.0244748
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0242173
PLEC plectin 0.0234959
EFNA5 ephrin-A5 0.0232246
NRIP1 nuclear receptor interacting protein 1 0.0226728
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0220857
UTRN utrophin 0.0218555
NCOR2 nuclear receptor corepressor 2 0.0217274
ITCH itchy E3 ubiquitin protein ligase 0.0216796
ABI3BP ABI family, member 3 (NESH) binding protein 0.021485
FNIP1 folliculin interacting protein 1 0.0212237
TXNIP thioredoxin interacting protein 0.0210097
OSBPL6 oxysterol binding protein-like 6 0.0206637
TENM4 teneurin transmembrane protein 4 0.0204899
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0200333
RASA3 RAS p21 protein activator 3 0.0199317
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0199024
EIF4A2 eukaryotic translation initiation factor 4A2 0.019739
ZMYND8 zinc finger, MYND-type containing 8 0.0197049
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0196539
KLHL24 kelch-like family member 24 0.0193147
MEGF6 multiple EGF-like-domains 6 0.0191666
KCTD12 potassium channel tetramerization domain containing 12 0.0186731
BACE2 beta-site APP-cleaving enzyme 2 0.0181952
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0181618
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0181247
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0179444
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0178323
DOK5 docking protein 5 0.0176605
MYOF myoferlin 0.0173334
CNTNAP3 contactin associated protein-like 3 0.0172125
DOCK9 dedicator of cytokinesis 9 0.0169747
JMJD1C jumonji domain containing 1C 0.0166133
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0165654
C4BPB complement component 4 binding protein, beta 0.0165495
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0160805
PICALM phosphatidylinositol binding clathrin assembly protein 0.0158841
MAML3 mastermind-like 3 (Drosophila) 0.0156537
ARHGAP21 Rho GTPase activating protein 21 0.0154503
EXOC4 exocyst complex component 4 0.0154185
LRRC8C leucine rich repeat containing 8 family, member C 0.0154034
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.015385
ANXA11 annexin A11 0.0153384
DENND5A DENN/MADD domain containing 5A 0.0152804
PCDH1 protocadherin 1 0.0152371
IGF1R insulin-like growth factor 1 receptor 0.0151232
HLA-E major histocompatibility complex, class I, E 0.0151025
LYST lysosomal trafficking regulator 0.0150221
PHF3 PHD finger protein 3 0.0149914
N4BP2L2 NEDD4 binding protein 2-like 2 0.014706
SMYD3 SET and MYND domain containing 3 0.014573
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.01457
RPRD1B regulation of nuclear pre-mRNA domain containing 1B 0.0145268
RNF217 ring finger protein 217 0.014492
MYH9 myosin, heavy chain 9, non-muscle 0.0144788
FRMD6 FERM domain containing 6 0.0143652
MECOM MDS1 and EVI1 complex locus 0.0143213
SPATA13 spermatogenesis associated 13 0.0141791
PACS1 phosphofurin acidic cluster sorting protein 1 0.0141459
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0141282
DSPP dentin sialophosphoprotein 0.0139449
NCOA6 nuclear receptor coactivator 6 0.0138828
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0137746
USP33 ubiquitin specific peptidase 33 0.0135971
RICTOR RPTOR independent companion of MTOR, complex 2 0.0135704
MT1E metallothionein 1E 0.0134274
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0133649
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.0133358
GOLGB1 golgin B1 0.0132997
UBE2H ubiquitin-conjugating enzyme E2H 0.0132876
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0132638
MROH1 maestro heat-like repeat family member 1 0.0132397
SESTD1 SEC14 and spectrin domains 1 0.0132337
HDAC9 histone deacetylase 9 0.0131995
CDKN2A cyclin-dependent kinase inhibitor 2A 0.0131816

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.189464
TMSB10 thymosin beta 10 -0.155733
PTMA prothymosin, alpha -0.0997163
B2M beta-2-microglobulin -0.099199
RPS21 ribosomal protein S21 -0.097885
MT2A metallothionein 2A -0.0838706
IFITM3 interferon induced transmembrane protein 3 -0.0764245
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0752871
TPT1 tumor protein, translationally-controlled 1 -0.0741815
FLNB filamin B, beta -0.0736801
RPLP2 ribosomal protein, large, P2 -0.0735395
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0725692
RPS6 ribosomal protein S6 -0.0717587
S100A10 S100 calcium binding protein A10 -0.0715162
LMNA lamin A/C -0.0651561
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.062016
RPS8 ribosomal protein S8 -0.0619939
POTEF POTE ankyrin domain family, member F -0.0597898
VCL vinculin -0.0582759
S100A6 S100 calcium binding protein A6 -0.0573529
GNAS GNAS complex locus -0.0565896
RPLP1 ribosomal protein, large, P1 -0.0549115
RPL11 ribosomal protein L11 -0.0545395
RPS19 ribosomal protein S19 -0.0543786
NDRG1 N-myc downstream regulated 1 -0.054202
HLA-B major histocompatibility complex, class I, B -0.0524143
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0521046
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0504637
PGK1 phosphoglycerate kinase 1 -0.0501934
S100A2 S100 calcium binding protein A2 -0.0499936
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0489559
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0487709
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0476388
RPS13 ribosomal protein S13 -0.0471859
ITGA6 integrin, alpha 6 -0.0456319
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0443144
IFITM1 interferon induced transmembrane protein 1 -0.044247
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0442294
IFI6 interferon, alpha-inducible protein 6 -0.0441135
RPS3 ribosomal protein S3 -0.0437047
FTL ferritin, light polypeptide -0.0436617
LDHA lactate dehydrogenase A -0.0435151
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0432922
RPL35A ribosomal protein L35a -0.0428916
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0421344
ENO1 enolase 1, (alpha) -0.0408743
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.0403115
RPL23 ribosomal protein L23 -0.0402819
CNRIP1 cannabinoid receptor interacting protein 1 -0.0394811
S100A11 S100 calcium binding protein A11 -0.0393386
RPS24 ribosomal protein S24 -0.0389955
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0384675
RPL32 ribosomal protein L32 -0.0380656
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0376147
INTS6 integrator complex subunit 6 -0.0375161
RPL12 ribosomal protein L12 -0.0370169
RPL8 ribosomal protein L8 -0.0368326
RPL34 ribosomal protein L34 -0.0364405
IGF2 insulin-like growth factor 2 -0.0363566
KTN1 kinectin 1 (kinesin receptor) -0.0359773
PKM pyruvate kinase, muscle -0.035871
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0352359
MBNL1 muscleblind-like splicing regulator 1 -0.0350678
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0350459
RPL36 ribosomal protein L36 -0.0349285
RPL19 ribosomal protein L19 -0.0342399
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.034201
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0341145
STC1 stanniocalcin 1 -0.0337086
TPX2 TPX2, microtubule-associated -0.0335353
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0332497
RPL36A ribosomal protein L36a -0.0327423
ANLN anillin, actin binding protein -0.0326269
EGR1 early growth response 1 -0.0324612
LOC112694756 uncharaterized LOC112694756 -0.0322557
VDAC1 voltage-dependent anion channel 1 -0.0322302
KRT17 keratin 17, type I -0.0321298
IFI27 interferon, alpha-inducible protein 27 -0.0318739
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0317979
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.031701
ATP5F1E ATP synthase F1 subunit epsilon -0.0316316
SEC61G Sec61 gamma subunit -0.0313291
ALCAM activated leukocyte cell adhesion molecule -0.030938
MKI67 marker of proliferation Ki-67 -0.0306461
DST dystonin -0.0302004
RPL37A ribosomal protein L37a -0.0299275
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0297768
TAGLN2 transgelin 2 -0.0291392
RPS25 ribosomal protein S25 -0.0290858
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0289346
RPL7A ribosomal protein L7a -0.0288797
S100A4 S100 calcium binding protein A4 -0.0287867
RPS12 ribosomal protein S12 -0.0286673
RPS29 ribosomal protein S29 -0.0285469
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0284902
ACTN4 actinin, alpha 4 -0.0283535
CENPF centromere protein F, 350/400kDa -0.0279104
RPS14 ribosomal protein S14 -0.0278804
ACTG1 actin gamma 1 -0.0278167
ZNFX1 zinc finger, NFX1-type containing 1 -0.0278077