Resveratrol_NCI-H1792 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in NCI-H1792 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PCBP2 poly(rC) binding protein 2 0.117596
SMAD3 SMAD family member 3 0.0956888
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0825773
NAV2 neuron navigator 2 0.0794341
FNDC3B fibronectin type III domain containing 3B 0.0711896
EFNA5 ephrin-A5 0.0672769
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0669506
VEGFA vascular endothelial growth factor A 0.0612434
GRB10 growth factor receptor-bound protein 10 0.0573912
SOD2 superoxide dismutase 2, mitochondrial 0.0459505
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0447277
IGFBP3 insulin-like growth factor binding protein 3 0.0397916
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0361981
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0354235
ZNF292 zinc finger protein 292 0.034695
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.0345097
PDE4D phosphodiesterase 4D, cAMP-specific 0.0343634
LRMDA leucine rich melanocyte differentiation associated 0.0322571
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0319745
RUNX1 runt-related transcription factor 1 0.031671
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0315937
RAD51B RAD51 paralog B 0.0314459
SEPTIN9 septin 9 0.0307745
VMP1 vacuole membrane protein 1 0.0307674
HDAC9 histone deacetylase 9 0.0307268
TGM2 transglutaminase 2 0.0296218
PRELID2 PRELI domain containing 2 0.0293442
RARB retinoic acid receptor, beta 0.0292085
KDM2A lysine (K)-specific demethylase 2A 0.0289355
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.0269593
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.0263821
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0259811
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0248614
IFI44L interferon-induced protein 44-like 0.0243725
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0242428
NOTCH2 notch 2 0.0242172
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0240113
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.0239068
LCOR ligand dependent nuclear receptor corepressor 0.0238216
SIK3 SIK family kinase 3 0.0235876
APLP2 amyloid beta (A4) precursor-like protein 2 0.0234071
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0233863
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0230349
FAM13A family with sequence similarity 13, member A 0.0227393
RAB8B RAB8B, member RAS oncogene family 0.022731
TRIO trio Rho guanine nucleotide exchange factor 0.0222837
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0220566
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0217857
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0217276
NHSL1 NHS-like 1 0.021719
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.0214831
GPHN gephyrin 0.0212998
ECE1 endothelin converting enzyme 1 0.0212372
ETV6 ets variant 6 0.0204012
SMYD3 SET and MYND domain containing 3 0.0203897
TNIP1 TNFAIP3 interacting protein 1 0.0202973
EEF2 eukaryotic translation elongation factor 2 0.0201702
RPL3 ribosomal protein L3 0.019982
NBAS neuroblastoma amplified sequence 0.0196527
SKAP2 src kinase associated phosphoprotein 2 0.019591
RPL4 ribosomal protein L4 0.0195751
ZNF638 zinc finger protein 638 0.0194237
CDK19 cyclin-dependent kinase 19 0.0194106
CCSER1 coiled-coil serine-rich protein 1 0.0193991
EGFR epidermal growth factor receptor 0.0193744
PTK2 protein tyrosine kinase 2 0.0192464
WDPCP WD repeat containing planar cell polarity effector 0.0192024
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0190775
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0189102
BACE2 beta-site APP-cleaving enzyme 2 0.0188149
PFKP phosphofructokinase, platelet 0.0187719
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0186126
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 0.0183831
FBXL13 F-box and leucine-rich repeat protein 13 0.0183663
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0182436
MIPOL1 mirror-image polydactyly 1 0.0180885
ANO6 anoctamin 6 0.0179884
HELZ helicase with zinc finger 0.0179801
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0178134
FAM219A family with sequence similarity 219, member A 0.0176847
ATXN1 ataxin 1 0.0175496
LNPEP leucyl/cystinyl aminopeptidase 0.0172343
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0171789
WWTR1 WW domain containing transcription regulator 1 0.0171189
TOP6BL TOP6B like initiator of meiotic double strand breaks 0.0170314
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.0169797
CNOT12 CCR4-NOT transcription complex subunit 12 0.0168184
LHFPL2 lipoma HMGIC fusion partner-like 2 0.016772
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0166414
ZCCHC7 zinc finger, CCHC domain containing 7 0.0164865
LGALS12 lectin, galactoside-binding, soluble, 12 0.0164353
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0164098
ANXA1 annexin A1 0.0164036
MAML3 mastermind-like 3 (Drosophila) 0.0163739
AMPD3 adenosine monophosphate deaminase 3 0.0163379
UBA6 ubiquitin-like modifier activating enzyme 6 0.0161532
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0161264
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.0159717
HIPK2 homeodomain interacting protein kinase 2 0.0159638
DPYSL3 dihydropyrimidinase-like 3 0.0158886

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.223929
VIM vimentin -0.145539
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.119081
CXCL8 chemokine (C-X-C motif) ligand 8 -0.111557
TFPI2 tissue factor pathway inhibitor 2 -0.104465
PTMA prothymosin, alpha -0.10031
FN1 fibronectin 1 -0.0984415
STC1 stanniocalcin 1 -0.0932681
GLCCI1 glucocorticoid induced 1 -0.0862345
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0829084
TPT1 tumor protein, translationally-controlled 1 -0.0816915
FTL ferritin, light polypeptide -0.0752531
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0733472
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0729584
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0695426
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0679222
BTG1 B-cell translocation gene 1, anti-proliferative -0.0658799
S100A6 S100 calcium binding protein A6 -0.0651336
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0632629
IER3 immediate early response 3 -0.0604773
ZMYND8 zinc finger, MYND-type containing 8 -0.0600206
WSB1 WD repeat and SOCS box containing 1 -0.0588866
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0571887
RAB1A RAB1A, member RAS oncogene family -0.0563147
TM4SF1 transmembrane 4 L six family member 1 -0.0554764
ZEB2 zinc finger E-box binding homeobox 2 -0.0547389
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0499046
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0489624
EIF1 eukaryotic translation initiation factor 1 -0.048481
OSMR oncostatin M receptor -0.0482382
LMAN1 lectin, mannose-binding, 1 -0.0480432
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0465309
RBM39 RNA binding motif protein 39 -0.0464517
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0464234
ARHGAP5 Rho GTPase activating protein 5 -0.0431273
NRG1 neuregulin 1 -0.0418776
PGK1 phosphoglycerate kinase 1 -0.0418298
KDM3A lysine (K)-specific demethylase 3A -0.0411356
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0404424
NAP1L1 nucleosome assembly protein 1-like 1 -0.0381482
RPLP1 ribosomal protein, large, P1 -0.0377463
SLC38A1 solute carrier family 38, member 1 -0.0374084
RPL35A ribosomal protein L35a -0.0360392
NUMB numb homolog (Drosophila) -0.0359398
IFI6 interferon, alpha-inducible protein 6 -0.0354913
S100A10 S100 calcium binding protein A10 -0.0351539
NPC1 Niemann-Pick disease, type C1 -0.0349426
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0340806
BMERB1 bMERB domain containing 1 -0.0339979
NAMPT nicotinamide phosphoribosyltransferase -0.0337318
RPL34 ribosomal protein L34 -0.0331516
EIF5B eukaryotic translation initiation factor 5B -0.0327506
TMSB4X thymosin beta 4, X-linked -0.0322896
DLG1 discs, large homolog 1 (Drosophila) -0.0321093
RPS24 ribosomal protein S24 -0.0319269
TMEM263 transmembrane protein 263 -0.0318368
GNAS GNAS complex locus -0.0313957
GOLGA4 golgin A4 -0.0310939
RPS21 ribosomal protein S21 -0.0306928
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0306158
CD44 CD44 molecule (Indian blood group) -0.0305876
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0305841
HLA-B major histocompatibility complex, class I, B -0.0305002
ZNF804A zinc finger protein 804A -0.0303678
KPNB1 karyopherin (importin) beta 1 -0.0300681
PRRC2C proline-rich coiled-coil 2C -0.0300075
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0297665
ANXA2 annexin A2 -0.0294687
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0294017
GCC2 GRIP and coiled-coil domain containing 2 -0.0293084
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0289946
RPLP2 ribosomal protein, large, P2 -0.0289858
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0289317
HMGA2 high mobility group AT-hook 2 -0.0288779
MTSS1 metastasis suppressor 1 -0.0288024
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0287615
CP ceruloplasmin (ferroxidase) -0.0286171
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0286081
TPM4 tropomyosin 4 -0.0282191
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0280966
DENND4A DENN/MADD domain containing 4A -0.0276667
CAVIN1 caveolae associated protein 1 -0.0276249
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0273292
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0272106
RPL37A ribosomal protein L37a -0.0271445
ACTG1 actin gamma 1 -0.0269366
RAB13 RAB13, member RAS oncogene family -0.026729
RPS6 ribosomal protein S6 -0.0266017
BZW1 basic leucine zipper and W2 domains 1 -0.0265934
RPS29 ribosomal protein S29 -0.0261948
RPS19 ribosomal protein S19 -0.0261825
THBD thrombomodulin -0.0261596
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0260384
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0260096
NAV3 neuron navigator 3 -0.0259859
B2M beta-2-microglobulin -0.0258106
PTPRF protein tyrosine phosphatase, receptor type, F -0.0257983
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0257386
RPL32 ribosomal protein L32 -0.0255008
CLMP CXADR-like membrane protein -0.0253636