Resveratrol_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Resveratrol perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Resveratrol_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0917909
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0720879
TMSB4X thymosin beta 4, X-linked 0.0669574
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0593461
EML4 echinoderm microtubule associated protein like 4 0.0555548
NAMPT nicotinamide phosphoribosyltransferase 0.0535224
ZNF292 zinc finger protein 292 0.052763
ADAM10 ADAM metallopeptidase domain 10 0.0521747
TJP1 tight junction protein 1 0.0517211
RTN4 reticulon 4 0.0505303
TXNRD1 thioredoxin reductase 1 0.0495605
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0487405
RHOA ras homolog family member A 0.0486513
GOLGA4 golgin A4 0.0484821
SSBP2 single-stranded DNA binding protein 2 0.0465775
ANXA1 annexin A1 0.0465133
QKI QKI, KH domain containing, RNA binding 0.0454448
KDM3A lysine (K)-specific demethylase 3A 0.0446904
CCNL1 cyclin L1 0.0442792
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0435434
KMT2E lysine (K)-specific methyltransferase 2E 0.0434118
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0429902
WAC WW domain containing adaptor with coiled-coil 0.0423045
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0422979
TXNIP thioredoxin interacting protein 0.0417133
PCBP2 poly(rC) binding protein 2 0.0416848
EIF4A2 eukaryotic translation initiation factor 4A2 0.0403504
EZR ezrin 0.0399871
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0379322
XPO1 exportin 1 0.0373658
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0368414
NBAS neuroblastoma amplified sequence 0.0361543
NCKAP1 NCK-associated protein 1 0.0361331
ZFAND3 zinc finger, AN1-type domain 3 0.0354064
SQSTM1 sequestosome 1 0.0353086
JMJD1C jumonji domain containing 1C 0.0351917
CDC73 cell division cycle 73 0.0350266
RNF145 ring finger protein 145 0.0348616
RLF rearranged L-myc fusion 0.0332964
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0326105
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0322869
MEF2A myocyte enhancer factor 2A 0.031971
SETD5 SET domain containing 5 0.0318804
POTEF POTE ankyrin domain family, member F 0.0317686
FXR1 fragile X mental retardation, autosomal homolog 1 0.0316581
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0311124
CHD1 chromodomain helicase DNA binding protein 1 0.0310062
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0309744
KDM6A lysine (K)-specific demethylase 6A 0.0303286
EEF2 eukaryotic translation elongation factor 2 0.0301238
PKM pyruvate kinase, muscle 0.0295311
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.028867
NUP58 nucleoporin 58 0.0288566
USP3 ubiquitin specific peptidase 3 0.0282945
DSTN destrin (actin depolymerizing factor) 0.027928
ADAM9 ADAM metallopeptidase domain 9 0.0275301
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0272967
STRN3 striatin, calmodulin binding protein 3 0.0268322
HEATR1 HEAT repeat containing 1 0.0266829
RIOK3 RIO kinase 3 0.0266634
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.0265211
PDS5B PDS5 cohesin associated factor B 0.0265166
ASXL1 additional sex combs like transcriptional regulator 1 0.0264908
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0264878
STAG2 stromal antigen 2 0.0262868
PIAS1 protein inhibitor of activated STAT, 1 0.0262009
RAB6A RAB6A, member RAS oncogene family 0.0259805
TMF1 TATA element modulatory factor 1 0.0259778
TFG TRK-fused gene 0.0259098
TOP2B topoisomerase (DNA) II beta 180kDa 0.0259009
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0258769
RICTOR RPTOR independent companion of MTOR, complex 2 0.0257565
ARL15 ADP-ribosylation factor-like 15 0.0257136
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0251577
GOLM2 golgi membrane protein 2 0.024911
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0247391
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0246894
TBK1 TANK-binding kinase 1 0.0246021
SNX9 sorting nexin 9 0.0244001
LRRC58 leucine rich repeat containing 58 0.0243532
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0242769
UBA6 ubiquitin-like modifier activating enzyme 6 0.0240634
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0239569
DENND4A DENN/MADD domain containing 4A 0.0239057
SPAG9 sperm associated antigen 9 0.023837
TAOK1 TAO kinase 1 0.0236978
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0236841
SEC23A Sec23 homolog A (S. cerevisiae) 0.023674
RAD21 RAD21 homolog (S. pombe) 0.0236611
TP53BP1 tumor protein p53 binding protein 1 0.0235921
ARHGAP12 Rho GTPase activating protein 12 0.0235668
PLK2 polo-like kinase 2 0.0235141
YTHDC1 YTH domain containing 1 0.0234986
RBMS2 RNA binding motif, single stranded interacting protein 2 0.023443
RCOR3 REST corepressor 3 0.0234279
SRP54 signal recognition particle 54kDa 0.0233918
TPD52 tumor protein D52 0.0233766
FOXN2 forkhead box N2 0.02324
PDE8A phosphodiesterase 8A 0.0232095
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.023133

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.243814
TPT1 tumor protein, translationally-controlled 1 -0.136658
RPL35A ribosomal protein L35a -0.0961159
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0928886
PDE4B phosphodiesterase 4B, cAMP-specific -0.0889718
NPAS2 neuronal PAS domain protein 2 -0.086961
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0861292
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0778875
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0730118
RPL9 ribosomal protein L9 -0.0704291
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0702611
RPL37A ribosomal protein L37a -0.0690929
AHNAK AHNAK nucleoprotein -0.0689336
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0646983
PRELID2 PRELI domain containing 2 -0.0636369
RPS3 ribosomal protein S3 -0.0623306
RPS12 ribosomal protein S12 -0.0598232
MYO5C myosin VC -0.0582731
RPL23 ribosomal protein L23 -0.0542179
BMP10 bone morphogenetic protein 10 -0.0541502
RFC3 replication factor C (activator 1) 3, 38kDa -0.0534343
RPLP2 ribosomal protein, large, P2 -0.0515624
RPL26 ribosomal protein L26 -0.0508876
RPS8 ribosomal protein S8 -0.0504415
TAS2R14 taste receptor, type 2, member 14 -0.0503782
RPL11 ribosomal protein L11 -0.0476742
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -0.047505
FLNB filamin B, beta -0.0451331
UNC13A unc-13 homolog A (C. elegans) -0.0448097
RPS27A ribosomal protein S27a -0.0444776
RPL36 ribosomal protein L36 -0.044458
RPS13 ribosomal protein S13 -0.0438759
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0435502
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0434371
TMSB10 thymosin beta 10 -0.0427539
TTC28 tetratricopeptide repeat domain 28 -0.0422217
RPS25 ribosomal protein S25 -0.0422079
NAV2 neuron navigator 2 -0.0415943
RPL31 ribosomal protein L31 -0.0415711
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0412757
GLI2 GLI family zinc finger 2 -0.0407525
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0406419
VCL vinculin -0.0405168
RPL12 ribosomal protein L12 -0.0402397
ASPH aspartate beta-hydroxylase -0.0395966
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0386858
MKI67 marker of proliferation Ki-67 -0.038274
RPS24 ribosomal protein S24 -0.0381616
TUBB4B tubulin, beta 4B class IVb -0.0377495
TM4SF1 transmembrane 4 L six family member 1 -0.0377455
RPS6 ribosomal protein S6 -0.0359432
EXT1 exostosin glycosyltransferase 1 -0.0359222
TTC3 tetratricopeptide repeat domain 3 -0.0353605
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0347264
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0344511
RPLP1 ribosomal protein, large, P1 -0.034243
RAD51B RAD51 paralog B -0.0338435
DIAPH3 diaphanous-related formin 3 -0.033668
RRBP1 ribosome binding protein 1 -0.0332643
FHIT fragile histidine triad -0.033235
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0328752
MT2A metallothionein 2A -0.032579
PATJ PATJ crumbs cell polarity complex component -0.0323739
FUS FUS RNA binding protein -0.0323711
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0322734
MACROD2 MACRO domain containing 2 -0.0320276
CCND1 cyclin D1 -0.0319702
INTS6 integrator complex subunit 6 -0.0318428
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0314284
CENPE centromere protein E, 312kDa -0.0312093
SMC4 structural maintenance of chromosomes 4 -0.0307556
RPS19 ribosomal protein S19 -0.0307408
PDE4D phosphodiesterase 4D, cAMP-specific -0.030708
NBEA neurobeachin -0.0303081
HJURP Holliday junction recognition protein -0.0302205
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0302027
MAPK8 mitogen-activated protein kinase 8 -0.0296222
GLI3 GLI family zinc finger 3 -0.029325
MYOF myoferlin -0.0286831
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0282722
RPS17 ribosomal protein S17 -0.028117
TBC1D22A TBC1 domain family, member 22A -0.0280671
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0280307
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.02799
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0278106
S100A4 S100 calcium binding protein A4 -0.0276883
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0276023
MYL12B myosin, light chain 12B, regulatory -0.0270688
CAMTA1 calmodulin binding transcription activator 1 -0.0269155
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0263916
MSI2 musashi RNA-binding protein 2 -0.0263855
ENO1 enolase 1, (alpha) -0.0262202
ACTN4 actinin, alpha 4 -0.0259071
CAMKMT calmodulin-lysine N-methyltransferase -0.0258218
GSE1 Gse1 coiled-coil protein -0.0256091
CLTA clathrin, light chain A -0.025593
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0254489
ZMYND8 zinc finger, MYND-type containing 8 -0.0254183
ENO2 enolase 2 (gamma, neuronal) -0.0253614
NSD2 nuclear receptor binding SET domain protein 2 -0.0251063